Ankrd25 (BC010245) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR209360L3V
- LentiORF®
Lenti ORF particles, Ankrd25 (Myc-DDK-tagged) - Mouse ankyrin repeat domain 25 (cDNA clone MGC:12143 IMAGE:3710765), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
Product Data | |
Product Name | Ankrd25 (BC010245) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | MGC12143, MGC7734 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | BC010245 |
ORF Size | 1821 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR209360).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | BC010245.1 |
RefSeq Size | 3427 bp |
RefSeq ORF | 1823 bp |
Locus ID | 235041 |
Gene Summary | Involved in transcription regulation by sequestering in the cytoplasm nuclear receptor coactivators such as NCOA1, NCOA2 and NCOA3 (By similarity). Involved in regulation of caspase-independent apoptosis by sequestering the proapoptotic factor AIFM1 in mitochondria (By similarity). Pro-apoptotic stimuli can induce its proteasomal degradation allowing the translocation of AIFM1 to the nucleus to induce apoptosis (By similarity). Involved in the negative control of vitamin D receptor signaling pathway (By similarity). Involved in actin stress fibers formation through its interaction with ARHGDIA and the regulation of the Rho signaling pathway (PubMed:25961457). May thereby play a role in cell adhesion and migration, regulating for instance podocytes migration during development of the kidney (PubMed:25961457). Through the Rho signaling pathway may also regulate cell proliferation (PubMed:16024821).[UniProtKB/Swiss-Prot Function] |
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