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Dach2 (NM_001142570) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR209355L3V
- LentiORF®
-
Lenti ORF particles, Dach2 (Myc-DDK-tagged) - Mouse dachshund 2 (Drosophila) (Dach2), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 10,735.00
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Specifications
| Product Data | |
| Product Name | Dach2 (NM_001142570) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 9430028N04Rik |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001142570 |
| ORF Size | 1821 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR209355).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001142570.1, NP_001136042.1 |
| RefSeq Size | 5991 bp |
| RefSeq ORF | 1821 bp |
| Locus ID | 93837 |
| Gene Summary | Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression. Probably binds to DNA via its DACHbox-N domain.[UniProtKB/Swiss-Prot Function] |
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