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Ppm1d (BC023492) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR209279L3V
- LentiORF®
-
Lenti ORF particles, Ppm1d (Myc-DDK-tagged) - Mouse protein phosphatase 1D magnesium-dependent, delta isoform (cDNA clone MGC:32306 IMAGE:5026376), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | Ppm1d (BC023492) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AV338790; Wip1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | BC023492 |
| ORF Size | 1791 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR209279).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC023492.1 |
| RefSeq Size | 2023 bp |
| RefSeq ORF | 1793 bp |
| Locus ID | 53892 |
| Gene Summary | Involved in the negative regulation of p53 expression. Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins. Mediates MAPK14 dephosphorylation and inactivation (By similarity). Is also an important regulator of global heterochromatin silencing and critical in maintaining genome integrity (PubMed:24135283).[UniProtKB/Swiss-Prot Function] |
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