Slc22a1 (NM_009202) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR208809L4V
- LentiORF®
Lenti ORF particles, Slc22a1 (GFP-tagged) - Mouse solute carrier family 22 (organic cation transporter), member 1 (Slc22a1), 200ul, >10^7 TU/mL
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CNY 11,305.00
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Specifications
Product Data | |
Product Name | Slc22a1 (NM_009202) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | Lx1; Oct1; Orct; Orct1 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_009202 |
ORF Size | 1671 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR208809).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_009202.2 |
RefSeq Size | 1994 bp |
RefSeq ORF | 1671 bp |
Locus ID | 20517 |
Gene Summary | Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and pH-independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. The choline transport is activated by MMTS. Regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase.[UniProtKB/Swiss-Prot Function] |
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