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Dtx1 (BC053055) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR208731L3V
- LentiORF®
-
Lenti ORF particles, Dtx1 (Myc-DDK-tagged) - Mouse deltex 1 homolog (Drosophila) (cDNA clone MGC:62339 IMAGE:5685525), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | Dtx1 (BC053055) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Fxit1; mKIAA4160 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | BC053055 |
| ORF Size | 1647 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR208731).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC053055.1 |
| RefSeq Size | 2882 bp |
| RefSeq ORF | 1649 bp |
| Locus ID | 14357 |
| Gene Summary | Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1. Functions as an ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.[UniProtKB/Swiss-Prot Function] |
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