Trim27 (NM_009054) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR208363L4V
- LentiORF®
Lenti ORF particles, Trim27 (GFP-tagged) - Mouse tripartite motif-containing 27 (Trim27), 200ul, >10^7 TU/mL
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CNY 10,830.00
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Specifications
Product Data | |
Product Name | Trim27 (NM_009054) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | AW538890; Gm19403; Rfp |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_009054 |
ORF Size | 1539 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR208363).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_009054.3, NP_033080.2 |
RefSeq Size | 4204 bp |
RefSeq ORF | 1542 bp |
Locus ID | 19720 |
Gene Summary | E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity; mediates the formation of 'Lys-48'-linked polyubiquitin chains; the function inhibits CD4 T-cell activation. Acts as a regulator of retrograde transport: together with MAGEL2, mediates the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASHC1, leading to promote endosomal F-actin assembly. Has a transcriptional repressor activity. Induces apoptosis by activating Jun N-terminal kinase and p38 kinase and also increases caspase-3-like activity independently of mitochondrial events. May function in male germ cell development. Has DNA-binding activity and preferentially bound to double-stranded DNA.[UniProtKB/Swiss-Prot Function] |
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