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Gas8 (NM_018855) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR207834L3V
- LentiORF®
-
Lenti ORF particles, Gas8 (Myc-DDK-tagged) - Mouse growth arrest specific 8 (Gas8), 200ul, >10^7 TU/mL
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CNY 9,215.00
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Specifications
| Product Data | |
| Product Name | Gas8 (NM_018855) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Gas11 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_018855 |
| ORF Size | 1437 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR207834).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_018855.2, NP_061343.2 |
| RefSeq Size | 1687 bp |
| RefSeq ORF | 1437 bp |
| Locus ID | 104346 |
| Gene Summary | Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker (By similarity). Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by faciltating the trafficking of SMO into the cilium and the stimulation of SMO activity in a GRK2-dependent manner (PubMed:17366626, PubMed:21659505, PubMed:27472056). May play a role in the spermatozoa motility (PubMed:11751847).[UniProtKB/Swiss-Prot Function] |
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