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Coro1c (NM_011779) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR207591L3V
- LentiORF®
-
Lenti ORF particles, Coro1c (Myc-DDK-tagged) - Mouse coronin, actin binding protein 1C (Coro1c), 200ul, >10^7 TU/mL
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CNY 9,215.00
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规格
| Cited in 1 publication. |
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经常一起买 (3)
Specifications
| Product Data | |
| Product Name | Coro1c (NM_011779) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AL022675; AW455561; AW548837 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_011779 |
| ORF Size | 1425 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR207591).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_011779.2, NP_035909.2 |
| RefSeq Size | 3436 bp |
| RefSeq ORF | 1425 bp |
| Locus ID | 23790 |
| Gene Summary | Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1 (PubMed:25074804, PubMed:25925950). Increases the presence of activated RAC1 at the leading edge of migrating cells (PubMed:25074804, PubMed:25925950). Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments (PubMed:27178841). Required for normal cell proliferation, cell migration, and normal formation of lamellipodia (PubMed:27178841). Plays a role in endoplasmic reticulum-associated endosome fission: localizes to endosome membrane tubules and promotes recruitment of TMCC1, leading to recruitment of the endoplasmic reticulum to endosome tubules for fission. Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane (By similarity). Required for normal distribution of mitochondria within cells (PubMed:27178841).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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YBX1 gene silencing inhibits migratory and invasive potential via CORO1C in breast cancer in vitro
,null,
BMC Cancer
,PubMed ID 28302118
[Coro1c]
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