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Dmap1 (NM_023178) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR207480L4V
- LentiORF®
-
Lenti ORF particles, Dmap1 (GFP-tagged) - Mouse DNA methyltransferase 1-associated protein 1 (Dmap1), 200ul, >10^7 TU/mL
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CNY 10,165.00
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Specifications
| Product Data | |
| Product Name | Dmap1 (NM_023178) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1500016M21Rik; Dmtap1; DNMAP1; DNMTAP1; mKIAA1425 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_023178 |
| ORF Size | 1407 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR207480).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_023178.2, NP_075667.1 |
| RefSeq Size | 1543 bp |
| RefSeq ORF | 1407 bp |
| Locus ID | 66233 |
| Gene Summary | Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Participates in the nuclear localization of URI1 and increases its transcriptional corepressor activity (By similarity).[UniProtKB/Swiss-Prot Function] |
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