United States
Germany
Japan
United Kingdom
China
Micu2 (NM_028643) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR206892L3V
- LentiORF®
-
Lenti ORF particles, Efha1 (Myc-DDK-tagged) - Mouse EF hand domain family A1 (Efha1), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 7,410.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Micu2 (NM_028643) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1110008L20Rik; 4833427E09Rik; AU041871; Efha1; Smhs2 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_028643 |
| ORF Size | 1299 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR206892).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_028643.1 |
| RefSeq Size | 2310 bp |
| RefSeq ORF | 1299 bp |
| Locus ID | 68514 |
| Gene Summary | Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low (PubMed:23409044, PubMed:24560927). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium (PubMed:24560927). MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting Ca(2+), avoiding energy dissipation and cell-death triggering (PubMed:24560927).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
