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Sgms1 (NM_144792) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR206639L3V
- LentiORF®
-
Lenti ORF particles, Sgms1 (Myc-DDK-tagged) - Mouse sphingomyelin synthase 1 (Sgms1), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Sgms1 (NM_144792) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 9530058O11Rik; AI841905; C80702; Mob; Sms1; Sor1; Tmem23 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_144792 |
| ORF Size | 1260 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR206639).
|
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_144792.3 |
| RefSeq Size | 3624 bp |
| RefSeq ORF | 1260 bp |
| Locus ID | 208449 |
| Gene Summary | Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types (By similarity). Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.[UniProtKB/Swiss-Prot Function] |
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