Angptl4 (NM_020581) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR206437L4V
- LentiORF®
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Lenti ORF particles, Angptl4 (GFP-tagged) - Mouse angiopoietin-like 4 (Angptl4), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
Product Data | |
Product Name | Angptl4 (NM_020581) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | Arp4; Bk89; Fiaf; Hfarp; Ng27; Pgar; Pgarg; Pp1158 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_020581 |
ORF Size | 1230 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR206437).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_020581.1, NP_065606.1 |
RefSeq Size | 1858 bp |
RefSeq ORF | 1233 bp |
Locus ID | 57875 |
Gene Summary | Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism (PubMed:15837923, PubMed:17609370, PubMed:29899519). May also play a role in regulating glucose homeostasis and insulin sensitivity (PubMed:15837923, PubMed:29899519). Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (PubMed:14583458, PubMed:17130448, PubMed:21832056). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro) (By similarity). Depending on context, may modulate tumor-related angiogenesis (Probable).[UniProtKB/Swiss-Prot Function] |
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