Ptrf (Cavin1) (NM_008986) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR206126L4V

  • LentiORF®

Lenti ORF particles, Ptrf (GFP-tagged) - Mouse polymerase I and transcript release factor (Ptrf), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 8,360.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Ptrf (Cavin1) (NM_008986) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 2310075E07Rik; AW546441; Cav-p60; Cavin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_008986
ORF Size 1176 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR206126).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_008986.2, NP_033012.1
RefSeq Size 3218 bp
RefSeq ORF 1179 bp
Locus ID 19285
Gene Summary Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues (PubMed:18191225, PubMed:18840361, PubMed:18056712, PubMed:30188967). Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of calveolin-1 (CAV1) (PubMed:19546242). Essential for normal oligomerization of CAV1 (PubMed:23652019). Promotes ribosomal transcriptional activity in response to metabolic challenges in the adipocytes and plays an important role in the formation of the ribosomal transcriptional loop (PubMed:27528195). Dissociates transcription complexes paused by DNA-bound TTF1, thereby releasing both RNA polymerase I and pre-RNA from the template (PubMed:9582279, PubMed:11139612). The caveolae biogenesis pathway is required for the secretion of proteins such as GASK1A (PubMed:30188967).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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