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Casp4 (NM_007609) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR205770L4V
- LentiORF®
-
Lenti ORF particles, Casp4 (GFP-tagged) - Mouse caspase 4, apoptosis-related cysteine peptidase (Casp4), 200ul, >10^7 TU/mL
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CNY 8,360.00
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| Product Data | |
| Product Name | Casp4 (NM_007609) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Cas; CASP-4; CASP-11; Casp11; Caspa; Caspl; ich-; ich-3 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_007609 |
| ORF Size | 1119 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR205770).
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| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_007609.1, NP_031635.1 |
| RefSeq Size | 1350 bp |
| RefSeq ORF | 1122 bp |
| Locus ID | 12363 |
| Gene Summary | This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. [provided by RefSeq, Apr 2015] |
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