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Trib1 (NM_144549) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR205755L3V
- LentiORF®
-
Lenti ORF particles, Trib1 (Myc-DDK-tagged) - Mouse tribbles homolog 1 (Drosophila) (Trib1), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Trib1 (NM_144549) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | A530090O15Rik; TRB-1; Trb1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_144549 |
| ORF Size | 1119 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR205755).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_144549.2, NP_653132.1 |
| RefSeq Size | 4026 bp |
| RefSeq ORF | 1119 bp |
| Locus ID | 211770 |
| Gene Summary | Adapter protein involved in protein degradation by interacting with COP1 ubiquitin ligase (PubMed:23515163, PubMed:20410507). Promotes CEBPA degradation and inhibits its function (PubMed:20410507). Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain (PubMed:24003916, PubMed:23515163). Regulates myeloid cell differentiation by altering the expression of CEBPA in a COP1-dependent manner (PubMed:23515163). Interacts with MAPK kinases and regulates activation of MAP kinases, but has no kinase activity (By similarity).[UniProtKB/Swiss-Prot Function] |
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