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Trib1 (NM_144549) Mouse Untagged Clone
CAT＃: MC208084
Trib1 (untagged) - Mouse tribbles homolog 1 (Drosophila) (Trib1), (10ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | A530090O15Rik; TRB-1; Trb1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC208084 representing NM_144549
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCGGGTCGGTCCCGTGCGTTTTGCCCTGAGCGGCGCCTCGCAGCCCCGCGGTCCGGGTCTACTGTTTC CGGCTGCCCGGGGAACCCCGGCCAAACGCCTGCTGGACACGGACGACGCGGGGGCAGTGGCGGCCAAGTG TCCGCGCCTCTCTGAGTGCTCGAGTCCCCCCGACTACCTCAGTCCCCCTGGCTCGCCCTGCAGCCCTCAG CCTCCGCCCTCCACGCAGGGGACCGGCGGCAGCTGTGTGAGCTCACCCGGGCCCAGCCGAATCGCCGACT ACCTGCTGCTACCCCTAGCTGAGCGCGAGCATGTGTCCCGGGCACTGTGCATCCACACCGGCCGCGAGCT GCGCTGCAAGGAATTCCCCATTAAACACTACCAGGACAAAATCAGGCCTTACATCCAGCTGCCGTCCCAT AGCAACATCACTGGCATTGTGGAGGTGCTCCTTGGTGAGAGCAAGGCCTACGTCTTCTTCGAGAAGGACT TTGGAGACATGCACTCCTATGTGCGGAGCCGAAAACGGCTTCGGGAAGAGGAGGCCGCTCGGCTCTTCAA GCAGATTGTTTCCGCCGTCGCCCACTGCCACCAGTCGGCCATCGTGCTGGGGGACCTGAAGCTCAGGAAG TTCGTCTTCTCCACCGAGGAGAGAACCCAGCTTAGACTGGAAAGCCTGGAAGATACTCACATCATTAAGG GTGAAGATGATGCGCTGTCAGATAAACATGGCTGCCCAGCCTACGTGAGCCCCGAGATCCTCAACACTAC TGGGACCTACTCTGGAAAGGCGGCGGACGTCTGGAGCCTCGGGGTGATGCTCTATACGCTTTTGGTCGGA CGATACCCCTTTCATGACTCAGATCCGAGTGCCCTTTTTTCCAAAATCCGCCGTGGACAGTTCTGCATTC CTGAGCACGTCTCCCCCAAAGCCAGGTGCCTCATCCGAAGCCTCCTAAGACGAGAACCTTCTGAGAGACT CACAGCTCCTCAGATCTTACTCCATCCCTGGTTCGAGTATGTCTTGGAACCGGGCTATGTTGACTCAGAA ATAGGAACTTCAGACCAGATTGTTCCTGAGTACCAGGAGGACAGTGACATAAGTTCCTTCTTCTGCTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_144549 |
| Insert Size | 1119 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_144549.4, NP_653132.1 |
| RefSeq Size | 4026 bp |
| RefSeq ORF | 1119 bp |
| Locus ID | 211770 |
| UniProt ID | Q8K4K4 |
| Gene Summary | Adapter protein involved in protein degradation by interacting with COP1 ubiquitin ligase (PubMed:23515163, PubMed:20410507). Promotes CEBPA degradation and inhibits its function (PubMed:20410507). Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain (PubMed:24003916, PubMed:23515163). Regulates myeloid cell differentiation by altering the expression of CEBPA in a COP1-dependent manner (PubMed:23515163). Interacts with MAPK kinases and regulates activation of MAP kinases, but has no kinase activity (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG205755 | Trib1 (tGFP-tagged) - Mouse tribbles homolog 1 (Drosophila) (Trib1) |
CNY 3,140.00 |
|
| MR205755 | Trib1 (Myc-DDK-tagged) - Mouse tribbles homolog 1 (Drosophila) (Trib1) |
CNY 2,850.00 |
|
| MR205755L3 | Lenti ORF clone of Trib1 (Myc-DDK-tagged) - Mouse tribbles homolog 1 (Drosophila) (Trib1) |
CNY 4,750.00 |
|
| MR205755L4 | Lenti ORF clone of Trib1 (mGFP-tagged) - Mouse tribbles homolog 1 (Drosophila) (Trib1) |
CNY 4,750.00 |
