Ubiad1 (BC015303) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR204995L3V
- LentiORF®
Lenti ORF particles, Ubiad1 (Myc-DDK-tagged) - Mouse UbiA prenyltransferase domain containing 1 (cDNA clone MGC:19220 IMAGE:4241204), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
Product Data | |
Product Name | Ubiad1 (BC015303) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 1200002M06Rik; AI426463; AW320947; Tere1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | BC015303 |
ORF Size | 1008 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR204995).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | BC015303, AAH15303 |
RefSeq Size | 2694 bp |
RefSeq ORF | 1010 bp |
Locus ID | 71707 |
Gene Summary | Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform required for endothelial cell development. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosynthetic enzyme: coenzyme Q10, also named ubiquinone, plays an important antioxidant role in the cardiovascular system. Mediates biosynthesis of coenzyme Q10 in the Golgi membrane, leading to protect cardiovascular tissues from NOS3/eNOS-dependent oxidative stress (By similarity).[UniProtKB/Swiss-Prot Function] |
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