Fas (NM_007987) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR204789L3V
- LentiORF®
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Lenti ORF particles, Fas (Myc-DDK-tagged) - Mouse Fas (TNF receptor superfamily member 6) (Fas), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
Product Data | |
Product Name | Fas (NM_007987) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | AI196731; APO1; APT1; CD95; lpr; TNFR6; Tnfrsf6 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_007987 |
ORF Size | 984 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR204789).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_007987.2, NP_032013.2 |
RefSeq Size | 1486 bp |
RefSeq ORF | 984 bp |
Locus ID | 14102 |
Gene Summary | Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity).[UniProtKB/Swiss-Prot Function] |
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