Ppp6c (NM_024209) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR204292L3V
- LentiORF®
Lenti ORF particles, Ppp6c (Myc-DDK-tagged) - Mouse protein phosphatase 6, catalytic subunit (Ppp6c), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | Ppp6c (NM_024209) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 2310003C10Rik; Pp6C |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_024209 |
ORF Size | 918 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR204292).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_024209.1 |
RefSeq Size | 1583 bp |
RefSeq ORF | 918 bp |
Locus ID | 67857 |
Gene Summary | Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. During mitosis, regulates spindle positioning. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7. Participates also in the innate immune defense against viruses by desphosphorylating RIG-I/DDX58, an essential step that triggers RIG-I/DDX58-mediated signaling activation.[UniProtKB/Swiss-Prot Function] |
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