Exosc7 (BC052656) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR203992L4V

  • LentiORF®

Lenti ORF particles, Exosc7 (GFP-tagged) - Mouse exosome component 7 (cDNA clone MGC:60453 IMAGE:30041585), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 11,115.00


货期*
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规格
    • 200 ul

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经常一起买 (2)
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Specifications

Product Data
Product Name Exosc7 (BC052656) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 2610002K22Rik; AV212732; mKIAA0116
Vector pLenti-C-mGFP-P2A-Puro
ACCN BC052656
ORF Size 873 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR203992).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq BC052656, AAH52656
RefSeq Size 1030 bp
RefSeq ORF 875 bp
Locus ID 66446
Gene Summary Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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