Snf8 (NM_033568) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR203337L3V
- LentiORF®
Lenti ORF particles, Snf8 (Myc-DDK-tagged) - Mouse SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) (Snf8), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | Snf8 (NM_033568) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | D11Moh34 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_033568 |
ORF Size | 777 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR203337).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_033568.1 |
RefSeq Size | 947 bp |
RefSeq ORF | 777 bp |
Locus ID | 27681 |
Gene Summary | Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).[UniProtKB/Swiss-Prot Function] |
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