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Rab1a (NM_008996) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR202153L4V
- LentiORF®
-
Lenti ORF particles, Rab1 (GFP-tagged) - Mouse RAB1, member RAS oncogene family (Rab1), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Rab1a (NM_008996) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Gtbp; mKIAA3012; Rab-1; Rab1; Ypt1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_008996 |
| ORF Size | 618 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR202153).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_008996.3 |
| RefSeq Size | 2657 bp |
| RefSeq ORF | 618 bp |
| Locus ID | 19324 |
| Gene Summary | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell membrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria (By similarity). Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport.[UniProtKB/Swiss-Prot Function] |
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