United States
Germany
Japan
United Kingdom
China
Hmgb3 (NM_008253) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR202042L4V
- LentiORF®
-
Lenti ORF particles, Hmgb3 (GFP-tagged) - Mouse high mobility group box 3 (Hmgb3), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,360.00
货期*
详询
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Product Name | Hmgb3 (NM_008253) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Hmg2a; Hmg4 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_008253 |
| ORF Size | 603 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR202042).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_008253.4, NP_032279.1 |
| RefSeq Size | 1751 bp |
| RefSeq ORF | 603 bp |
| Locus ID | 15354 |
| Gene Summary | Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (PubMed:19890330). Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling (PubMed:12714519, PubMed:15358624, PubMed:16945912).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
