Gm2a (NM_010299) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR201862L3V
- LentiORF®
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Lenti ORF particles, Gm2a (Myc-DDK-tagged) - Mouse GM2 ganglioside activator protein (Gm2a), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | Gm2a (NM_010299) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | AA408702; AW215435; GM2-AP; SAP-3 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_010299 |
ORF Size | 582 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR201862).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_010299.2 |
RefSeq Size | 4257 bp |
RefSeq ORF | 582 bp |
Locus ID | 14667 |
Gene Summary | Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3. The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity.[UniProtKB/Swiss-Prot Function] |
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