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Gm2a (NM_010299) Mouse Untagged Clone
CAT＃: MC205674
Gm2a (untagged) - Mouse GM2 ganglioside activator protein (Gm2a), (10ug)
CNY 2,400.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AA408702; AW215435; GM2-AP; SAP-3 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC004651
GGCAGCCGTGAGTCGCATTGCCTAGACCGACACGGAGGACCATCGCCATGCACCGTCTACCGCTGCTGCT CCTGCTGGGCTTGCTGCTCGCAGGCTCCGTCGCCCCTGCGCGCCTCGTCCCGAAGCGCCTTTCCCAACTT GGTGGCTTCTCCTGGGATAACTGTGATGAAGGAAAGGACCCTGCAGTGATCAAAAGCCTCACGATCCAAC CTGACCCCATTGTGGTTCCTGGAGATGTAGTCGTCAGCCTTGAGGGCAAGACCAGCGTTCCCCTCACTGC TCCTCAGAAGGTGGAGCTCACCGTGGAGAAGGAAGTGGCTGGCTTCTGGGTCAAGATTCCTTGTGTAGAA CAGCTAGGCAGCTGTAGCTACGAGAACATCTGTGACCTGATAGACGAATACATTCCTCCTGGAGAGAGCT GCCCAGAGCCCCTGCACACCTACGGGCTGCCCTGCCACTGTCCCTTCAAGGAAGGTACCTACTCACTACC CACGAGCAACTTCACAGTGCCTGACCTAGAGCTACCGAGCTGGCTGAGCACAGGCAACTACCGCATCCAG AGTATCTTGAGCAGTGGTGGGAAGCGCCTGGGCTGCATCAAGATTGCTGCCTCTCTCAAGGGCAGATAAC CTGGCAGCAGCCACCACAGAATGAAGGGGCACCAGCACGGCAGGCCTCTTCTTCTGTGTTCCGGTGCCCA GGCCTGCCTGCCTCTAACTCTATCCTCCTACGGTTCTCTACCCTCTCTGGAAATCATTGCAACCTGACCT GAGGGAGGATGGACCAGGCCCAACATCTGATGGGCTGTAAGCCATGCTCCTTTGCACCCCTACCAACTTT CTAAGAATTTCTTTCGTATCCAAAACAGTCAAGGAATGGGAACCAACATGTTTGGGAATCCTAAGGTCAA AACTGGCCCAACCTGGACCTCCTGGAGTTATGCTCACCCCACTTCTTTGTTTTAGTCACCAACTTTAAAA CCAGGATAACCGTATTAATTTCTCATTCCATCCTGAGCCTCTCTTCCTGCAAAGAGGTCTAGGTAGTCAG TCTTGGGTCCCTCTATTAACTTCTGTGATTAACTGCATTCTCTTTGCAACTTAACTTGTCAACACTGGGG CTGACAGATCCTGAAGAGGCAGGGTGGTGTGTGACAGAAACCTGTGAGAGTTATTGTTGGGCATGCTCCA GTAACCCTTGGCAAAGCACAGGTACCTGTAGGGCCAAGCCGAAGACCTAGGGAGGCACAGCAATCACTTC TGGGAGCGATGCCCATTTTTCCTTTTTCCTTTTTTTTTTTTTTTTTTTTTGGTATGATGCCTTCAAGAAT GGGATGGCATTCCTTATACCTGACAAGAAACAACCAAAAAAACCAATAGCACATGTGCTCTGGTGCCAGG TGGCCAGGGTCTGGAATGGCATATCTAGTTCTAAAGAGGTGCAGTCCCCTGCAAGTTCCATGTAAGGAAT GTTGCCAGATATTTGCAACATTTTTCTTCCTTAGGCCCCAAACCCAGCCGTTTATATGAAATTGTAGAAT TTTTAACTATTGGAAACAAATGGTTTTTTTATATATACTTACTATGCAGGCCAAAGGGGCCCCACGGACT CACCCAGGGACATAATCTGGCTCCCAGGTGGCTGCTTTTCCTCACATCTGTTCATCTTCTCAATCTCAAG TTATCTGGCCGCATCTCTTCCCCCTTCAAGGTCAAGTCCTTGGTGCCTGGCCTCAAAGAGGGCTCAGCCT GCACTAGAGCAGGTCTACATGGCTTCTGAGAGCTGGGCACTGTGCCAACTTCCGAGCCATCACCACCAGA GTAGAGGGGTTCACACTGGAGTAGATCCCACCTAGCAGCCACCACGTGGAACAGGGGTCCTGTGAAGAGA GTGGGTCCCACATCAGGTTGCACCATGACAACTTCCTGAGCCTCCTCGGACAGCCCAGGTTCTGGACTAG AAGACTGGTCTGGCAATAAATCTTTTTAACTTGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_010299 |
| Insert Size | 582 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC004651, AAH04651 |
| RefSeq Size | 2024 bp |
| RefSeq ORF | 582 bp |
| Locus ID | 14667 |
| UniProt ID | Q60648 |
| Gene Summary | Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3. The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG201862 | Gm2a (tGFP-tagged) - Mouse GM2 ganglioside activator protein (Gm2a) |
CNY 4,000.00 |
|
| MR201862 | Gm2a (Myc-DDK-tagged) - Mouse GM2 ganglioside activator protein (Gm2a) |
CNY 2,400.00 |
|
| MR201862L3 | Lenti ORF clone of Gm2a (Myc-DDK-tagged) - Mouse GM2 ganglioside activator protein (Gm2a) |
CNY 4,750.00 |
|
| MR201862L4 | Lenti ORF clone of Gm2a (mGFP-tagged) - Mouse GM2 ganglioside activator protein (Gm2a) |
CNY 4,750.00 |
