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Polr3g (BC030063) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR201232L4V
- LentiORF®
-
Lenti ORF particles, Polr3g (GFP-tagged) - Mouse polymerase (RNA) III (DNA directed) polypeptide G (cDNA clone MGC:41022 IMAGE:1446833), 200ul, >10^7 TU/mL
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CNY 7,505.00
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Specifications
| Product Data | |
| Product Name | Polr3g (BC030063) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | RPC7, RPC32 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | BC030063 |
| ORF Size | 480 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR201232).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC030063, AAH30063 |
| RefSeq Size | 753 bp |
| RefSeq ORF | 482 bp |
| Locus ID | 67486 |
| Gene Summary | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the RPC3/POLR3C-RPC6/POLR3F-RPC7/POLR3G subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway.[UniProtKB/Swiss-Prot Function] |
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