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Brms1 (BC003485) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR200909L3V
- LentiORF®
-
Lenti ORF particles, Brms1 (Myc-DDK-tagged) - Mouse breast cancer metastasis-suppressor 1 (cDNA clone MGC:6927 IMAGE:2811430), 200ul, >10^7 TU/mL
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CNY 6,650.00
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Specifications
| Product Data | |
| Product Name | Brms1 (BC003485) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AV003220; AW554636 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | BC003485 |
| ORF Size | 423 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR200909).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC003485, AAH03485 |
| RefSeq Size | 1212 bp |
| RefSeq ORF | 425 bp |
| Locus ID | 107392 |
| Gene Summary | Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis (By similarity).[UniProtKB/Swiss-Prot Function] |
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