Snw1 (BC049245) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR200327L4V

  • LentiORF®

Lenti ORF particles, MGC:55033 (GFP-tagged) - Mouse cDNA clone MGC:55033 IMAGE:4949466, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 7,505.00


货期*
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规格
    • 200 ul

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经常一起买 (2)
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Specifications

Product Data
Product Name Snw1 (BC049245) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 2310008B08Rik; AW048543; NCoA-62; Skiip; SKIP
Vector pLenti-C-mGFP-P2A-Puro
ACCN BC049245
ORF Size 306 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR200327).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq BC049245, AAH49245
RefSeq Size 935 bp
RefSeq ORF 308 bp
Locus ID 66354
Gene Summary Involved in pre-mRNA splicing as component of the spliceosome. Is required in the specific splicing of CDKN1A pre-mRNA; the function probably involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in transcriptional regulation. Modulates TGF-beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, RB1-mediated transcriptional repression, and retinoid-X receptor (RXR)- and vitamin D receptor (VDR)-dependent gene transcription in a cell line-specific manner probably involving coactivators NCOA1 and GRIP1. Is involved in NOTCH1-mediated transcriptional activation. Binds to multimerized forms of Notch intracellular domain (NICD) and is proposed to recruit transcriptional coactivators such as MAML1 to form an intermediate preactivation complex which associates with DNA-bound CBF-1/RBPJ to form a transcriptional activation complex by releasing SNW1 and redundant NOTCH1 NICD.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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