PEX1 (NM_001282678) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	HMLR1; PBD1A; PBD1B; ZWS; ZWS1
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001282678, the custom clone sequence may differ by one or more nucleotides ATGATGAAAGAACTTCAAACCAAGCAACTTCAGTCAAATACTGTGGGAATCACTGAATCTAATGAAAACG AGTCAGAGATTCCAGTTGACTCATCATCAGTAGCAAGTTTATGGACTATGATAGGAAGCATTTTTTCCTT TCAATCTGAGAAGAAACAAGAGACATCTTGGGGTTTAACTGAAATCAATGCATTCAAAAATATGCAGTCA AAGGTTGTTCCTCTAGACAATATTTTCAGAGTATGCAAATCTCAACCTCCTAGTATATATAACGCGTCAG CAACCTCTGTTTTTCATAAACACTGTGCCATTCATGTATTTCCATGGGACCAGGAATATTTTGATGTAGA GCCCAGCTTTACTGTGACATATGGAAAGCTAGTTAAGCTACTTTCTCCAAAGCAACAGCAAAGTAAAACA AAACAAAATGTGTTATCACCTGAAAAAGAGAAGCAGATGTCAGAGCCACTAGATCAAAAAAAAATTAGGT CAGATCATAATGAAGAAGATGAGAAGGCCTGTGTGCTACAAGTAGTCTGGAATGGACTTGAAGAATTGAA CAATGCCATCAAATATACCAAAAATGTAGAAGTTCTCCATCTTGGGAAAGTCTGGATTCCAGATGACCTG AGGAAGAGACTAAATATAGAAATGCATGCCGTAGTCAGGATAACTCCAGTGGAAGTTACCCCTAAAATTC CAAGATCTCTAAAGTTACAACCTAGAGAGAATTTACCTAAAGACATAAGTGAAGAAGACATAAAAACTGT ATTTTATTCATGGCTACAGCAGTCTACTACCACCATGCTTCCTTTGGTAATATCAGAGGAAGAATTTATT AAGCTGGAAACTAAAGATGGACTGAAGGAATTTTCTCTGAGTATAGTTCATTCTTGGGAAAAAGAAAAAG ATAAAAATATTTTTCTGTTGAGTCCCAATTTGCTGCAGAAGACTACAATACAAGTCCTTCTAGATCCTAT GGTAAAAGAAGAAAACAGTGAGGAAATTGACTTTATTCTTCCTTTTTTAAAGCTGAGCTCTTTGGGAGGA GTGAATTCCTTAGGCGTATCCTCCTTGGAGCACATCACTCACAGCCTCCTGGGACGCCCTTTGTCTCGGC AGCTGATGTCTCTTGTTGCAGGACTTAGGAATGGAGCTCTTTTACTCACAGGAGGAAAGGGAAGTGGAAA ATCAACTTTAGCCAAAGCAATCTGTAAAGAAGCATTTGACAAACTGGATGCCCATGTGGAGAGAGTTGAC TGTAAAGCTTTACGAGGAAAAAGGCTTGAAAACATACAAAAAACCCTAGAGGTGGCTTTCTCAGAGGCAG TGTGGATGCAGCCATCTGTTGTCCTGCTGGATGACCTTGACCTCATTGCTGGACTGCCTGCTGTCCCGGA ACATGAGCACAGTCCTGATGCGGTGCAGAGCCAGCGGCTTGCTCATGCTTTGAATGATATGATAAAAGAG TTTATCTCCATGGGAAGTTTGGTTGCACTGATTGCCACAAGTCAGTCTCAGCAATCTCTACATCCTTTAC TTGTTTCTGCTCAAGGAGTTCACATATTTCAGTGCGTCCAACACATTCAGCCTCCTAATCAGGAACAAAG ATGTGAAATTCTGTGTAATGTAATAAAAAATAAATTGGACTGTGATATAAACAAGTTCACCGATCTTGAC CTGCAGCATGTAGCTAAAGAAACTGGCGGGTTTGTGGCTAGAGATTTTACAGTACTTGTGGATCGAGCCA TACATTCTCGACTCTCTCGTCAGAGTATATCCACCAGAGAAAAATTAGTTTTAACAACATTGGACTTCCA AAAGGCTCTCCGCGGATTTCTTCCTGCGTCTTTGCGAAGTGTCAACCTGCATAAACCTAGAGACCTGGGT TGGGACAAGATTGGTGGGTTACATGAAGTTAGGCAGATACTCATGGATACTATCCAGTTACCTGCCAAGT ATCCAGAATTATTTGCAAACTTGCCCATACGACAAAGAACAGGAATACTGTTGTATGGTCCGCCTGGAAC AGGAAAAACCTTACTAGCTGGGGTAATTGCACGAGAGAGTAGAATGAATTTTATAAGTGTCAAGGGGCCA GAGTTACTCAGCAAATACATTGGAGCAAGTGAACAAGCTGTTCGGGATATTTTTATTAGAGCACAGGCTG CAAAGCCCTGCATTCTTTTCTTTGATGAATTTGAATCCATTGCTCCTCGGCGGGGTCATGATAATACAGG AGTTACAGACCGAGTAGTTAACCAGTTGCTGACTCAGTTGGATGGAGTAGAAGGCTTACAGGGTGTTTAT GTATTGGCTGCTACTAGTCGCCCTGACTTGATTGACCCTGCCCTGCTTAGGCCTGGTCGACTAGATAAAT GTGTATACTGTCCTCCTCCTGATCAGGTGTCACGTCTTGAAATTTTAAATGTCCTCAGTGACTCTCTACC TCTGGCAGATGATGTTGACCTTCAGCATGTAGCATCAGTAACTGACTCCTTTACTGGAGCTGATCTGAAA GCTTTACTTTACAATGCCCAATTGGAGGCCTTACATGGAATGCTGCTCTCGAGTGGACTCCAGGATGGAA GTTCCAGCTCTGATAGTGACCTAAGTCTGTCTTCAATGGTCTTTCTTAACCATAGCAGTGGCTCTGACGA TTCAGCTGGAGATGGAGAATGTGGCTTAGATCAGTCCCTTGTTTCTTTAGAGATGTCCGAGATCCTTCCA GATGAATCAAAATTCAATATGTACCGGCTCTACTTTGGAAGCTCTTATGAATCAGAACTTGGAAATGGAA CCTCTTCTGATTTGAGCTCACAATGTCTCTCTGCACCAAGCTCCATGACTCAGGATTTGCCTGGAGTTCC TGGGAAAGACCAGTTGTTTTCACAGCCTCCAGTGTTAAGGACAGCTTCACAAGAGGGTTGCCAAGAACTT ACACAAGAACAAAGAGATCAACTGAGGGCAGATATCAGTATTATCAAAGGCAGATACCGGAGCCAAAGTG GAGAGGACGAATCCATGAACCAACCAGGACCAATCAAAACCAGACTGGCTATTAGTCAGTCACATTTAAT GACTGCACTTGGTCACACAAGACCATCCATTAGTGAAGATGACTGGAAGAATTTTGCTGAGCTATATGAA AGCTTTCAAAATCCAAAGAGGAGAAAAAATCAAAGTGGAACAATGTTTCGACCTGGACAGAAAGTAACTT TAGCATAA
Restriction Sites	SgfI-RsrII
ACCN	NM_001282678
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001282678.1, NP_001269607.1
RefSeq Size	4427 bp
RefSeq ORF	3228 bp
Locus ID	5189
UniProt ID	O43933
Protein Families	Druggable Genome
Gene Summary	This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013] Transcript Variant: This variant (3) uses an alternate donor splice site in the 5' region, which results in translation initiation from an in-frame downstream start codon, compared to variant 1. The resulting isoform (3) has a shorter N-terminus compared to isoform 1.

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