KCNH6 (NM_001278919) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	ERG-2; ERG2; hERG-2; HERG2; Kv11.2
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001278919, the custom clone sequence may differ by one or more nucleotides ATGCCGGTCCGCAGGGGCCACGTCGCTCCCCAAAACACTTACCTGGACACCATCATCCGCAAGTTCGAGG GCCAAAGTCGGAAGTTCCTGATTGCCAATGCTCAGATGGAGAACTGCGCCATCATTTACTGCAACGACGG CTTCTGCGAACTCTTCGGCTACTCCCGAGTGGAGGTGATGCAGCAACCCTGCACCTGCGACTTCCTCACA GGCCCCAACACACCAAGCAGCGCCGTGTCCCGCCTAGCGCAGGCCCTGCTGGGGGCTGAGGAGTGCAAGG TGGACATCCTCTACTACCGCAAGGATGCCTCCAGCTTCCGCTGCCTGGTAGATGTGGTGCCCGTGAAGAA CGAGGACGGGGCTGTCATCATGTTCATTCTCAACTTCGAGGACCTGGCCCAGCTCCTGGCCAAGTGCAGC AGCCGCAGCTTGTCCCAGCGCCTGTTGTCCCAGAGCTTCCTGGGCTCCGAGGGCTCTCATGGCAGGCCAG GCGGACCAGGGCCAGGCACAGGCAGGGGCAAGTACAGGACCATCAGCCAGATCCCACAGTTCACGCTCAA CTTCGTGGAGTTCAACTTGGAGAAGCACCGCTCCAGCTCCACCACGGAGATTGAGATCATCGCGCCCCAT AAGGTGGTGGAGCGGACACAGAACGTCACTGAGAAGGTCACCCAGGTCCTGTCCCTGGGCGCGGATGTGC TGCCGGAGTACAAGCTGCAGGCGCCGCGCATCCACCGCTGGACCATCCTGCACTACAGCCCCTTCAAGGC CGTGTGGGACTGGCTCATCCTGCTGCTGGTCATCTACACGGCTGTCTTCACGCCCTACTCAGCCGCCTTC CTGCTCAGCGATCAGGACGAATCACGGCGTGGGGCCTGCAGCTATACCTGCAGTCCCCTCACTGTGGTGG ATCTCATCGTGGACATCATGTTCGTCGTGGACATCGTCATCAACTTCCGCACCACCTATGTCAACACCAA TGATGAGGTGGTCAGCCACCCCCGCCGCATCGCCGTCCACTACTTCAAGGGCTGGTTCCTCATTGACATG GTGGCCGCCATCCCTTTCGACCTCCTGATCTTCCGCACTGGCTCCGATGAGACCACAACCCTGATTGGGC TATTGAAGACAGCGCGGCTGCTGCGGCTGGTGCGCGTAGCACGGAAGCTGGACCGCTACTCTGAGTATGG GGCGGCTGTGCTCTTCTTGCTCATGTGCACCTTCGCGCTCATAGCGCACTGGCTGGCCTGCATCTGGTAC GCCATCGGCAATGTGGAGCGGCCCTACCTAGAACACAAGATCGGCTGGCTGGACAGCCTGGGTGTGCAGC TTGGCAAGCGCTACAACGGCAGCGACCCAGCCTCGGGCCCCTCGGTGCAGGACAAGTATGTCACAGCCCT CTACTTCACCTTCAGCAGCCTCACCAGCGTGGGCTTCGGCAATGTCTCGCCCAACACCAACTCCGAGAAG GTCTTCTCCATCTGCGTCATGCTCATCGGCTCCCTGATGTACGCCAGCATCTTCGGGAACGTGTCCGCGA TCATCCAGCGCCTGTACTCGGGCACCGCGCGCTACCACACGCAGATGCTGCGTGTCAAGGAGTTCATCCG CTTCCACCAGATCCCCAACCCACTGCGCCAGCGCCTGGAGGAGTATTTCCAGCACGCCTGGTCCTACACC AATGGCATTGACATGAACGCGGTGCTGAAGGGCTTCCCCGAGTGCCTGCAGGCTGACATCTGCCTGCACC TGCACCGCGCACTGCTGCAGCACTGCCCAGCTTTCAGCGGCGCCGGCAAGGGCTGCCTGCGCGCGCTAGC CGTCAAGTTCAAGACCACCCACGCGCCGCCTGGGGACACGCTGGTGCACCTCGGCGACGTGCTCTCCACC CTCTACTTCATCTCCCGAGGCTCCATCGAGATCCTGCGCGACGACGTGGTCGTGGCCATCCTAGGAAAGA ATGACATCTTTGGGGAACCCGTCAGCCTCCATGCCCAGCCAGGCAAGTCCAGTGCAGACGTGCGGGCTCT GACCTACTGCGACCTGCACAAGATCCAGCGGGCAGATCTGCTGGAGGTGCTGGACATGTACCCGGCCTTT GCGGAGAGCTTCTGGAGTAAGCTGGAGGTCACCTTCAACCTGCGGGACGCAGCCGGGGGTCTCCACTCAT CCCCCCGACAGGCTCCTGGCAGCCAAGACCACCAAGGTTTCTTTCTCAGTGACAACCAGTCAGATGCAGC CCCTCCCCTGAGCATCTCAGATGCATCTGGCCTCTGGCCTGAGCTACTGCAGGAAATGCCCCCAAGGCAC AGCCCCCAAAGCCCTCAGGAAGACCCAGATTGCTGGCCTCTGAAGCTGGGCTCCAGGCTAGAGCAGCTCC AGGCCCAGATGAACAGGCTGGAGTCCCGCGTGTCCTCAGACCTCAGCCGCATCTTGCAGCTCCTCCAGAA GCCCATGCCCCAGGGCCACGCCAGCTACATTCTGGAAGCCCCTGCCTCCAATGACCTGGCCTTGGTTCCT ATAGCCTCGGAGACGACGAGTCCAGGGCCCAGGCTGCCCCAGGGCTTTCTGCCTCCTGCACAGACCCCAA GCTATGGAGACTTGGATGACTGTAGTCCAAAGCACAGGAACTCCTCCCCCAGGATGCCTCACCTGGCTGT GGCAACGGACAAAACTCTGGCACCATCCTCAGAACAGGAACAGCCTGAGGGGCTCTGGCCACCCCTAGCC TCACCTCTACATCCCCTGGAAGTACAAGGACTCATCTGTGGTCCCTGCTTCTCCTCCCTCCCTGAACACC TTGGCTCTGTTCCCAAGCAGCTGGACTTCCAGAGACATGGCTCAGATCCTGGATTTGCAGGGAGTTGGGG CCACTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001278919
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001278919.1, NP_001265848.1
RefSeq Size	3783 bp
RefSeq ORF	2877 bp
Locus ID	81033
UniProt ID	Q9H252
Protein Families	Druggable Genome, Ion Channels: Other, Transmembrane
Gene Summary	Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013] Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. It encodes isoform 3, which is shorter, compared to isoform 1.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.