DORFIN (RNF19A) (NM_001280539) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	RNF19
Vector	pCMV6 series
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001280539, the custom clone sequence may differ by one or more nucleotides ATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAGGGCTGTGTGTAAACACTGACCCTGTCT CAATTCTAACAAGCATTTTAGACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTCAGTCCTC TGCTTCATCTGTGAGCTTGCCTTCAGTCAAAAAGGCACCCAAAAAAAGAAGAATTTCAATAGGCTCCCTG TTTCGGAGGAAAAAAGATAACAAACGTAAATCAAGGGAGCTAAATGGCGGGGTGGATGGAATTGCAAGTA TTGAAAGTATACATTCTGAAATGTGTACTGATAAGAACTCCATTTTCTCTACAAATACCTCTTCTGACAA TGGATTAACTTCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGTGCCTTTTGCGGCATTCT AAAGACAGATTTCCTGATATAATGACTTGTCATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAA GGATAGAAATCTCTGAAAGCAGAGTTAATATTAGTTGCCCAGAATGTACTGAACGGTTTAATCCCCATGA TATTCGCTTGATATTAAGTGATGATGTCTTGATGGAAAAATACGAAGAATTTATGCTTAGACGGTGGCTT GTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTGGATATGCTGTGATAGCATTTGGATGTG CCAGCTGTCCAAAATTAACTTGTGGGCGAGAGGGCTGTGGAACAGAGTTTTGCTACCACTGTAAACAGAT TTGGCACCCCAACCAGACCTGTGATGCTGCTCGACAAGAGAGAGCCCAGAGCTTACGTTTGAGAACTATA CGTTCTTCATCCATTAGTTATAGTCAAGAGTCTGGAGCAGCAGCTGATGATATAAAGCCATGTCCACGAT GTGCTGCTTATATAATAAAGATGAATGATGGGAGCTGCAATCACATGACATGTGCTGTTTGTGGTTGTGA GTTTTGTTGGTTGTGTATGAAAGAAATCTCAGATTTGCATTATCTAAGTCCATCAGGATGTACTTTTTGG GGGAAGAAACCCTGGAGCCGAAAGAAGAAAATATTGTGGCAACTGGGAACACTGGTTGGTGCTCCTGTCG GAATCGCTTTAATAGCTGGCATTGCTATTCCTGCAATGATTATTGGCATTCCTGTGTATGTGGGCCGCAA GATTCACAATCGCTATGAAGGCAAGGATGTTTCAAAGCACAAACGGAATTTGGCCATAGCAGGTGGTGTA ACGTTGTCTGTAATCGTGTCTCCAGTAGTAGCTGCAGTGACTGTAGGTATCGGTGTTCCTATTATGTTAG CTTATGTCTATGGCGTAGTTCCAATTTCTCTTTGTCGAAGCGGAGGTTGTGGAGTCTCAGCAGGCAATGG AAAAGGAGTTAGGATTGAATTTGATGATGAAAATGATATAAATGTTGGTGGAACTAACACAGCTGTAGAC ACAACATCAGTAGCAGAAGCAAGACACAACCCAAGCATAGGGGAGGGAAGTGTTGGTGGGCTGACTGGCA GTTTGAGTGCAAGTGGAAGCCACATGGATCGAATAGGAGCCATCCGAGACAACCTGAGTGAAACGGCCAG CACCATGGCACTAGCTGGAGCCAGTATAACGGGGAGTCTGTCAGGAAGTGCCATGGTAAACTGTTTTAAC AGGTTGGAAGTACAAGCAGATGTACAGAAAGAACGGTACAGTCTAAGTGGAGAATCTGGCACAGTCAGCT TGGGAACAGTTAGTGATAATGCCAGCACCAAAGCAATGGCAGGATCCATTCTGAATTCCTACATCCCATT GGACAAAGAAGGCAACAGTATGGAGGTGCAAGTAGATATTGAGTCAAAGCCATCCAAATTCAGGCACAAC AGTGGAAGCAGTAGTGTGGATGATGGCAGTGCCACCCGAAGTCATGCTGGCGGTTCATCCAGTGGCTTGC CTGAAGGTAAATCTAGTGCCACCAAGTGGTCCAAAGAAGCAACAGCAGGGAAAAAATCAAAAAGTGGTAA ACTGAGGAAAAAGGGTAACATGAAGATAAATGAGACGAGAGAGGACATGGATGCACAGTTGTTAGAACAA CAAAGCACGAACTCAAGTGAATTTGAGGCTCCATCCCTCAGTGACAGTATGCCTTCTGTAGCAGATTCTC ACTCTAGTCATTTTTCTGAATTTAGTTGTTCTGACCTAGAAAGCATGAAAACTTCTTGTAGTCATGGTTC CAGTGATTATCACACCCGCTTTGCTACTGTTAACATTCTTCCTGAGGTAGAAAATGACCGTCTGGAAAAT TCCCCACATCAGTGTAGCATTTCTGTGGTTACCCAAACTGCTTCCTGTTCAGAAGTTTCACAGTTGAATC ATATTGCTGAAGAACATGGTAACAATGGAATAAAACCTAATGTTGATTTATATTTTGGCGATGCACTAAA AGAAACAAATAACAACCACTCACATCAGACAATGGAATTAAAAGTTGCAATTCAGACTGAAATTTAG
Restriction Sites	SgfI-MluI
ACCN	NM_001280539
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001280539.1, NP_001267468.1
RefSeq Size	4318 bp
RefSeq ORF	2517 bp
Locus ID	25897
UniProt ID	Q9NV58
Protein Families	Druggable Genome, Transcription Factors, Transmembrane
Gene Summary	This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2, 3, 4, and 5 encode the same protein.

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