VAM1 (MPP6) (NM_001303037) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	p55T; PALS2; VAM-1; VAM1
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC336695 representing NM_001303037. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGCAGCAAGTCTTGGAAAACCTTACGGAGCTGCCCTCGTCTACTGGAGCAGAAGAAATAGACCTAATT TTCCTCAAGGGAATTATGGAGAATCCTATTGTAAAATCACTTGCTAAGGCTCATGAGAGGCTAGAAGAT TCCAAACTAGAAGCTGTCAGTGACAATAACTTGGAATTAGTCAATGAAATTCTTGAAGACATCACTCCT CTAATAAATGTGGATGAAAATGTGGCAGAATTGGTTGGTATACTCAAAGAACCTCACTTCCAGTCACTG TTGGAGGCCCATGATATTGTGGCATCAAAGTGTTATGATTCACCTCCATCAAGCCCAGAAATGAATAAT TCTTCTATCAATAATCAGTTATTACCAGTAGATGCCATTCGTATTCTTGGTATTCACAAAAGAGCTGGG GAACCACTGGGTGTGACATTTAGGGTTGAAAATAATGATCTGGTAATTGCCCGAATCCTCCATGGGGGA ATGATAGATCGACAAGGTCTACTTCATGTGGGAGATATAATTAAAGAAGTCAATGGCCATGAGGTTGGA AATAATCCAAAGGAATTACAAGAATTACTGAAAAATATTAGTGGAAGTGTCACCCTAAAAATCTTACCA AGTTATAGAGATACCATTACTCCTCAACAGGTATTTGTGAAGTGTCATTTTGATTATAATCCATACAAT GACAACCTAATACCTTGCAAAGAAGCAGGATTGAAGTTTTCCAAAGGAGAGATTCTTCAGATTGTAAAT AGAGAAGATCCAAATTGGTGGCAGGCTAGCCATGTAAAAGAGGGAGGAAGCGCTGGTCTCATTCCAAGC CAGTTCCTGGAAGAGAAGAGAAAGGCATTTGTTAGAAGAGACTGGGACAATTCAGGACCTTTTTGTGGA ACTATAAGTAGCAAAAAAAAGAAAAAGATGATGTATCTCACAACCAGAAATGCAGAATTTGATCGTCAT GAAATCCAGATATATGAGGAGGTAGCCAAAATGCCTCCCTTCCAGAGAAAAACATTAGTATTGATAGGA GCTCAAGGTGTAGGCCGAAGAAGCTTGAAAAACAGGTTCATAGTATTGAATCCCACTAGATTTGGAACT ACGGTGCCATTTACTTCACGGAAACCAAGGGAAGATGAAAAAGATGGCCAGGCATATAAGTTTGTGTCA CGATCTGAGATGGAAGCAGATATTAAAGCTGGAAAGTATTTGGAACATGGGGAATATGAAGGAAATCTC TATGGAACCAAAATTGATTCTATTCTTGAGGTTGTCCAAACTGGACGGACTTGCATTCTGGATGTCAAC CCACAAGCACTGAAAGTATTGAGGACATCAGAGTTTATGCCCTATGTGGTATTTATTGCGGCTCCGGAG CTAGAGACGTTACGTGCCATGCACAAGGCTGTGGTGGATGCAGGAATCACTACCAAGCTTCTGACCGAC TCTGACTTGAAGAAAACAGTGGATGAAAGTGCACGGATTCAGAGAGCATACAACCACTATTTTGATTTG ATCATCATAAATGATAATCTAGACAAAGCCTTTGAAAAACTGCAAACTGCCATAGAGAAACTGAGAATG GAACCACAGTGGGTCCCAATCAGCTGGGTTTACTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001303037
Insert Size	1623 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001303037.1
RefSeq Size	7972 bp
RefSeq ORF	1623 bp
Locus ID	51678
UniProt ID	Q9NZW5
Protein Families	Druggable Genome, Stem cell - Pluripotency
MW	61.1 kDa
Gene Summary	Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM, Mar 2008] Transcript Variant: This variant (2) lacks an exon in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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