CIRBP (NM_001300829) Human Untagged Clone
CAT#: SC335174
CIRBP (untagged) - Human cold inducible RNA binding protein (CIRBP), transcript variant 3
CNY 2,950.00
货期*
3周
规格
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经常一起买 (4)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CIRP |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>SC335174 representing NM_001300829.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCATCAGATGAAGGCAAACTTTTTGTTGGAGGGCTGAGTTTTGACACCAATGAGCAGTCGCTGGAG CAGGTCTTCTCAAAGTACGGACAGATCTCTGAAGTGGTGGTTGTGAAAGACAGGGAGACCCAGAGATCT CGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTAAGGATGCCATGATGGCCATGAATGGG AAGTCTGTAGATGGACGGCAGATCCGAGTAGACCAGGCAGGCAAGTCGTCAGACAACCGATCCCGTGGG TACCGTGGTGGCTCTGCCGGGGGCCGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCT AGAGGAGGAGGGGACCGAGGCTATGGGGGGAACCGGTTCGAGTCCAGGAGTGGGGGCTACGGAGGCTCC AGAGACTACTATAGCAGCCGGAGTCAGAGTGGTGGCTACAGTGACCGGAGCTCGGGCGGGTCCTACAGA GACAGTTATGACAGTTACGGTAAGTCACACTCCGAGGGCGCCACGCTGCTGTGGCCTGCGGTGGGAGCT CGGTTCACCTTGGTGCCCTCTCCAAGCACTTTAGGCTGGACACTCAGACCTTGTCACTGTGCTTGCCCA GAAGAGGCGCATCTGTCCTCTCAGAGCCATTTCTATCGCAGGACGCAAAAGCCAAATGAGACTGACCAA AAAGGCAAGGGAGAGCGAGGGCCCGCTGGGCAGTCAGCTAGGTGCATGTGTGGCCGCAGGCCAGCCTCC CTCGGCTGTGGGGGGTGGTTGCTCCCCGGCCGCAGGCCGCGCCCTGGTCTGGCCTCTGGGGTGAAGCTG CCTCTTGTTGCTTCGGTGCCTTTACACTGTGCCTGCTTCTTGTCCTCAGCTACACACAACGAGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
Restriction Sites | SgfI-MluI |
ACCN | NM_001300829 |
Insert Size | 894 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001300829.1 |
RefSeq Size | 1790 bp |
RefSeq ORF | 894 bp |
Locus ID | 1153 |
UniProt ID | Q14011 |
MW | 31.9 kDa |
Gene Summary | Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3' UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) encodes the longest isoform (3). |
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