F box protein 38 (FBXO38) (NM_001271723) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	Fbx38; HMN2D; MOKA; SP329
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC333096 representing NM_001271723. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGGGCCACGAAAGAAAAGTGTGAAAACATGTATCATGAATAATGAAATTCCAGAAGAAATGACAGCA GATGAAACAAAGGACTATATGAATCAACTTTCACATGAAGTACTTTGCCATATTTTTAGGTACCTCCCT CTGCAGGATATCATGTGTATGGAATGTCTTTCCCGGAAGCTAAAGGAAGCAGTGACCCTATATCTGCGA GTTGTGAGAGTTGTAGATCTCTGTGCAGGGCGGTGGTGGGAATACATGCCAAGTGGCTTTACAGATGCC AGTTTTCTAACACTATTAAAGAAGATGCCAGATGTTGAACAGCTATATGGCCTTCACCCTCGATACCTT GAGAGGCGAAGAGTAAGGGGCCATGAGGCTTTTAGCATTCCAGGAGTCCTAGAAGCTTTGCAGGCATGC CCAAACTTAGTGGGTGTGGAAACTTCTCATTTGGAGTTGGTAGAATCCATTTGGACATATATGCCCCAT GTTCATATTTTGGGGAAATTTCGTAATCGTAATGGAGCTTTTCCAATTCCTCCTGAAAATAAACTGAAA ATTCCTATAGGAGCCAAAATTCAAACTTTACATTTAGTTGGGGTGAATGTTCCTGAAATTCCTTGTATC CCAATGCTAAGGCACCTTTATATGAAGTGGGTAAGACTCACTAAACCACAGCCATTTAAAGACTTCCTT TGTATCAGCTTAAGAACTTTCGTCATGAGGAACTGTGCAGGACCCACAAATTCCTTGAAATATGTCCCT TTAGTAACAGGCTTAGCCTCTGCCCGAAACTTGGAACACTTAGAAATGGTTCGAGTTCCTTTCCTTGGA GGTCTTATCCAACATGTTGTTGAAGACAGTTGGAGATCAGGTGGTTTTAGAAATTTGCACACTATTGTT CTGGGAGCTTGCAAAAATGCTCTTGAAGTAGATCTTGGTTACCTCATCATTACTGCTGCCCGTAGGTTA CATGAAGTTCGGATCCAGCCTTCCCTAACCAAAGATGGTGTCTTTTCTGCCCTAAAGATGGCAGAGTTG GAGTTTCCCCAGTTTGAAACCCTTCATCTAGGATATGTAGATGAGTTTTTGCTACAGAGCAGAATGGCT AATGCGGATCTGGTGAAGTATGGTTTGGCTGATGTGGTAGAAAATCCTGGTATCATCACTGATATAGGG ATGAAAGCAGTCAATGAAGTTTTTTCCTGTATCAAATATCTGGCAATTTACAATTGCCCTCATCTACAC AACCCATACAATTGGATCTCAGACCACTCAAGATGGACTCGATTGGTTGATATCAACCTAGTACGGTGC CATGCTTTGAAGCTGGACTCTTTTGGCCAGTTTATTGAATTATTACCCAGCCTAGAGTTTATTTCACTG GATCAGATGTTTCGTGAACCACCCAAGGGTTGTGCTCGAGTTGGTCTGAGTGCAGGCACAGGAATTGGT GTTTCATCAGCTCTTGTTAGCAACCAGAACTCCAACAATGACGATAATAATGCCCAGAATAACAATGCC AACATCCACGACAACAATCACCATCATCCAGATGACTCAGACGAGGAGAATGACTTTCGGCAAGATCTG CAGCCAGGAGAGCAGCAGTTTGCAGCTGACGCATTAAATGAGATGGAAGACATCGTCCAAGAAGATGGA GAGGTGGTGGCCGAGAGTGGAAATAATACTCCAGCTCACAGCCAGGCAATTATTCCTGTGGATGTTGAT GAGGAACAAGCAGGACCCAGTGGTCTTCAGCGTGTAGTAAAACCAACCTCAATTACTGTTCATGATTCA GAGAGTGATGATGAAGAAGATAGTCTAGAACTCCAAGAAGTCTGGATTCCTAAGAACGGTACTCGGCGT TACTCTGAACGTGAAGAAAAAACTGGAGAGTCAGTGCAGTCCAGAGAATTGTCAGAAGTAGCCAAAACA AAGCCACGTCACGCCATGAAACGGAAGCGGACAGCAGATAAATCCACTAGTACAAGTGATCCTGTGATC GAGGATGACCATGTGCAGGTTCTTGTATTAAAATCCAAGAATCTTGTTGGAGTCACTATGACCAATTGT GGAATCACAGATCTAGTGCTAAAAGACTGTCCAAAGATGATGTTCATCCATGCTACCAGGTGCAGGGTA CTAAAACATTTAAAGGTAGAAAATGCACCAATTGTAAACCGATTTGACTATGCACAGTGCAAGAAACTG AACATGGATCAGGTACTAGACCAGATACTAAGAATGCCACCCGAGAGAAACCGCATCATATACCTACGC CCAATGCAGCAGGTGGACACTCTAACTTTGGAGCAGAAGCTATTTAGTGGTCCCTACCCCTATCACATC TGTATTATCCATGAATTCAGTAACCCTCCCAATGTCCGGAATAAGGTGCGCATTCGCAGCTGGATGGAC ACTATAGCAAACATCAATCAAGAGCTCATTAAATATGAATTCTTCCCTGAAGCCACTCGAAGTGAAGAA GACTTAAAGAAATACCCCAAGTACCCCTGGGGGAGAGAAATCTATACTTTAGAAGGTGTTGTGGATGGA GCTCCATATTCCATGATTTCTGACTTCCCTTGGCTGAGGTCATTACGAGCTGCAGAGCCCAACAGCTTC GCTCGATACGACTTTGAAGACGATGAAGAAAGCACTATCTATGCTCCTAGAAGGAAAGGACAGCTGTCT GCAGACATCTGTATGGAAACAATAGGAGAGGAAATTTCAGAGATGCGTCAGATGAAGAAGGGTGTATTT CAGCGAGTAGTGGCAATTTTTATCCACTATTGTGATGTCAATGGAGAGCCAGTTGAAGATGACTACATT TAA
Restriction Sites	SgfI-MluI
ACCN	NM_001271723
Insert Size	2832 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001271723.1
RefSeq Size	3712 bp
RefSeq ORF	2832 bp
Locus ID	81545
UniProt ID	Q6PIJ6
Protein Families	Druggable Genome
MW	107.7 kDa
Gene Summary	This gene encodes a large protein that contains an F-box domain and may participate in protein ubiquitination. The encoded protein is a transcriptional co-activator of Krueppel-like factor 7 (Klf7). A heterozygous mutation in this gene was found in individuals with autosomal dominant distal hereditary motor neuronopathy type IID. There is a pseudogene for this gene on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] Transcript Variant: This variant (3) lacks an alternate in-frame exon, compared to variant 1. This results in a shorter protein (isoform c), compared to isoform a.

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