EPB41L1 (NM_001258330) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	4.1N; MRD11
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC332665 representing NM_001258330. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGTTTTCTTGGGGAGGATCAATGAGGTAGAACCTGCAAAGGGCTTAGCAGAGAGCCTAGCACCTACT GAGCGCTCAGTAAAGAGCCTAGACATGGAGGAGAAGGACTACAGTGAGGCCGATGGCCTTTCGGAGAGG ACCACGCCCAGCAAGGCCCAGAAATCGCCCCAGAAGATTGCCAAGAAATACAAGAGTGCCATCTGCCGG GTCACTCTGCTTGATGCCTCGGAGTATGAGTGTGAGGTGGAGAAACATGGCCGGGGCCAGGTGCTGTTT GACCTGGTCTGTGAACACCTCAACCTCCTAGAGAAGGACTACTTCGGCCTGACCTTCTGTGATGCTGAC AGCCAGAAGAACTGGCTGGACCCCTCCAAGGAGATCAAGAAGCAGATCCGGAGTAGCCCCTGGAATTTT GCCTTCACAGTCAAGTTCTACCCGCCTGATCCTGCCCAGCTGACAGAAGACATCACAAGATACTACCTG TGCCTGCAGCTGCGGGCAGACATCATCACGGGCCGGCTGCCATGCTCCTTTGTCACGCATGCCCTACTG GGCTCCTACGCTGTGCAGGCTGAGCTGGGTGACTATGATGCTGAGGAGCATGTGGGCAACTATGTCAGC GAGCTCCGCTTCGCCCCTAACCAGACCCGGGAGCTGGAGGAGAGGATCATGGAGCTGCATAAGACATAT AGGGGGATGACCCCGGGAGAAGCAGAAATCCACTTCTTAGAGAATGCCAAGAAGCTTTCCATGTACGGA GTAGACCTGCACCATGCCAAGGACTCTGAGGGCATCGACATCATGTTAGGCGTTTGTGCCAATGGCCTG CTCATCTACCGGGACCGGCTGAGAATCAACCGCTTTGCCTGGCCCAAGATCCTCAAGATCTCCTACAAG AGGAGTAACTTCTATATCAAGATCCGGCCTGGGGAGTATGAGCAATTTGAGAGCACAATTGGCTTTAAG CTCCCAAACCACCGGTCAGCCAAGAGACTGTGGAAGGTCTGCATCGAGCATCATACATTCTTCCGGCTG GTGTCCCCTGAGCCCCCACCCAAGGGCTTCCTGGTGATGGGCTCCAAGTTCCGGTACAGTGGGAGGACC CAGGCACAGACTCGCCAGGCCAGCGCCCTCATTGACCGGCCTGCACCCTTCTTTGAGCGTTCTTCCAGC AAACGGTACACCATGTCCCGCAGCCTTGATGGAGCAGAGTTCTCCCGCCCAGCCTCGGTCAGCGAGAAC CATGATGCAGGGCCTGACGGTGACAAGCGGGATGAGGATGGCGAGTCTGGGGGGCAACGGTCAGAGGCT GAGGAGGGAGAGGTCAGGACTCCAACCAAGATCAAGGAGCTAAAGTTCTTAGACAAGCCAGAAGATGTC TTGCTGAAGCACCAGGCCAGCATCAATGAGCTCAAAAGGACCCTGAAGGAGCCCAACAGCAAACTCATC CACCGGGATCGAGACTGGGAACGGGAGCGCAGGCTGCCCTCCTCCCCCGCCTCCCCCTCCCCCAAGGGC ACCCCTGAGAAAGCCAATGAGCCCGTGAAAACAGAAACCATGACTGTCAGCAGTCTGGCCATTAGAAAG AAGATTGAGCCGGAGGCCGTACTGCAGACCAGAGTCTCCGCTATGGATAACACCCAGCAGGTTGATGGG AGTGCCTCAGTGGGGAGGGAGTTCATAGCAACCACTCCCTCCATCACCACGGAGACCATATCGACCACC ATGGAGAACAGTCTCAAGTCCGGGAAGGGGGCAGCTGCCATGATCCCAGGCCCACAGACGGTGGCCACG GAAATCCGTTCTCTTTCTCCGATCATCGGGAAAGATGTCCTCACCAGCACCTACGGCGCCACTGCGGAA ACCCTCTCAACCTCCACCACCACCCATGTCACCAAAACTGTGAAAGGAGGGTTTTCTGAGACAAGGATC GAGAAGCGAATCATCATTACTGGGGATGAAGATGTCGATCAAGACCAGGCCCTGGCTTTGGCCATCAAG GAGGCCAAACTGCAGCATCCTGATATGCTGGTAACCAAAGCTGTCGTATACAGAGAAACAGACCCATCC CCAGAGGAGAGGGACAAGAAGCCACAGGAATCCTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001258330
Insert Size	2106 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001258330.1
RefSeq Size	5745 bp
RefSeq ORF	2106 bp
Locus ID	2036
UniProt ID	Q9H4G0
Protein Families	Druggable Genome
Protein Pathways	Tight junction
MW	78.8 kDa
Gene Summary	Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015] Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence and lacks two alternate in-frame exons compared to variant 1. The resulting isoform (d) has a shorter and distinct N-terminus and lacks two alternate internal segments compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. CCDS Note: The 5'-most in-frame start codon is annotated for this transcript variant, which is supported by mRNA AK126875.1. It is present in a novel exon not found in other transcript variants for this gene. The annotated start codon is restricted to select higher primate species, including human, chimp, gorilla, orangutan and gibbon. It has a weak Kozak sequence and may sometimes be bypassed due to leaky scanning by ribosomes, which could result in use of a better conserved downstream start codon. There is no experimental evidence to indicate which start codon is preferentially used by this variant in vivo.

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