AKAP1 (NM_001242902) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	AKAP; AKAP84; AKAP121; AKAP149; D-AKAP1; PPP1R43; PRKA1; SAKAP84; TDRD17
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331923 representing NM_001242902. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGCAATCCAGTTCCGTTCGCTCTTCCCCTTGGCATTGCCTGGGATGCTGGCGCTCCTCGGCTGGTGG TGGTTTTTCTCTCGTAAAAAAGGCCATGTCAGCAGCCATGATGAGCAGCAGGTGGAGGCTGGTGCTGTG CAGCTGAGGGCTGACCCTGCCATCAAGGAACCTCTCCCCGTGGAAGACGTCTGTCCCAAAGTAGTGTCC ACACCCCCCAGTGTCACAGAGCCTCCAGAAAAGGAACTGTCCACCGTGAGCAAGCTGCCTGCAGAGCCC CCAGCATTGCTCCAGACACACCCACCTTGCCGAAGATCAGAGTCCTCGGGCATTCTTCCTAACACCACA GACATGAGATTGCGACCAGGAACACGCAGAGATGACAGTACAAAGCTGGAGCTAGCCCTGACAGGTGGT GAAGCCAAATCGATTCCTCTAGAGTGCCCCCTTTCATCCCCAAAGGGTGTACTATTCTCCAGCAAATCA GCTGAGGTGTGTAAGCAAGATTCCCCCTTCAGCAGGGTGCCAAGGAAGGTCCAGCCAGGCTACCCCGTA GTCCCCGCAGAGAAGCGTAGCTCTGGGGAGAGGGCAAGAGAGACAGGTGGGGCCGAAGGGACTGGTGAT GCCGTGTTGGGGGAAAAGGTGCTTGAAGAAGCTCTGTTGTCTCGGGAGCATGTCTTGGAATTGGAGAAC AGCAAGGGCCCCAGCCTGGCCTCTTTAGAGGGGGAAGAAGATAAGGGGAAGAGCAGCTCATCCCAGGTG GTGGGGCCAGTGCAGGAGGAAGAGTATGTAGCAGAGAAGTTGCCAAGTAGGTTCATCGAGTCGGCTCAC ACAGAGCTGGCAAAGGACGATGCGGCGCCAGCACCCCCAGTCGCAGACGCCAAAGCCCAGGATAGAGGT GTCGAGGGAGAACTGGGCAATGAGGAGAGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAG GGCTTGGATAGAAATGAGGAGAGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGATTAAG CGGGCTGCCTTCCAGATAATCTCCCAAGTGATCTCAGAAGCAACCGAACAGGTGCTGGCCACCACGGTT GGCAAGGTTGCAGGTCGTGTGTGTCAGGCCAGTCAGCTCCAAGGGCAGAAGGAAGAGAGCTGTGTCCCA GTTCACCAGAAAACTGTCTTGGGCCCAGACACTGCGGAGCCTGCCACAGCAGAGGCAGCTGTTGCCCCG CCGGATGCTGGCCTCCCCTTGCCAGGCCTACCAGCAGAGGGCTCACCACCACCAAAGACCTACGTGAGC TGCCTGAAGAGCCTTCTGTCCAGCCCCACCAAGGACAGTAAGCCAAATATCTCTGCACACCACATCTCC CTGGCCTCCTGCCTGGCACTGACCACCCCCAGTGAAGAGTTGCCGGACCGGGCAGGCATCCTGGTGGAA GATGCCACCTGTGTCACCTGCATGTCAGACAGCAGCCAAAGTGTCCCTTTGGTGGCTTCTCCAGGACAC TGCTCAGATTCTTTCAGCACTTCAGGGCTTGAAGACTCTTGCACAGAGACCAGCTCGAGCCCCAGGGAC AAGGCCATCACCCCGCCACTGCCAGAAAGTACTGTGCCCTTCAGCAATGGGGTGCTGAAGGGGGAGTTG TCAGACTTGGGGGCTGAGGATGGATGGACCATGGATGCGGAAGCAGATCATTCAGGAGGTTCTGACAGG AACAGCATGGATTCCGTGGATAGCTGTTGCAGTCTCAAGAAGACTGAGAGCTTCCAAAATGCCCAGGCA GGCTCCAACCCTAAGAAGGTCGACCTCATCATCTGGGAGATCGAGGTGCCAAAGCACTTAGTCGGTCGG CTAATTGGCAAGCAGGGGCGCTATGTGAGTTTTCTGAAGCAAACATCTGGTGCCAAGATCTACATTTCA ACCCTGCCTTACACCCAGAGCGTCCAGATCTGCCACATAGAAGGCTCTCAACATCATGTAGACAAAGCG CTGAACTTGATTGGGAAGAAGTTCAAAGAGCTGAACCTCACCAATATCTACGCTCCCCCATTGCCTTCA CTGGCACTGCCTTCTCTGCCGATGACATCCTGGCTCATGCTGCCTGATGGCATCACCGTGGAGGTCATT GTGGTCAACCAGGTCAATGCCGGGCACCTGTTCGTGCAGCAGCACACACACCCTACCTTCCACGCGCTG CGCAGCCTCGACCAGCAGATGTACCTCTGTTACTCTCAGCCTGGAATCCCCACCTTGCCCACCCCAGTG GAAATAACGGTCATCTGTGCCGCCCCTGGTGCGGACGGGGCCTGGTGGCGAGCCCAAGTGGTTGCCTCC TACGAGGAGACCAACGAAGTGGAGATTCGATACGTGGACTACGGCGGATATAAGAGGGTGAAAGTAGAC GTGCTCCGGCAAATCAGGTCTGACTTTGTCACCCTGCCGTTTCAGGGAGCAGAAGTCCTTCTGGACAGT GTGATGCCCCTGTCAGACGATGACCAGTTTTCACCGGAAGCAGATGCCGCCATGAGCGAGATGACGGGG AATACAGCACTGCTTGCTCAGGTGACAAGTTACAGTCCAACTGGTCTTCCTCTGATTCAGCTGTGGAGT GTGGTTGGAGATGAAGTGGTGTTGATAAACCGGTCCCTGGTGGAGCGAGGCCTTGCCCAGTGGGTAGAC AGCTACTACACAAGCCTTTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001242902
Insert Size	2712 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001242902.1
RefSeq Size	4048 bp
RefSeq ORF	2712 bp
Locus ID	8165
UniProt ID	Q92667
Protein Families	Druggable Genome, Transmembrane
MW	97.3 kDa
Gene Summary	The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) differs in the 5'UTR compared to variant 1. Variants 1, 2, and 3 encode the same protein.

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