SAFB (NM_001201338) Human Untagged Clone
CAT#: SC331410
SAFB (untagged) - Homo sapiens scaffold attachment factor B (SAFB), transcript variant 1
CNY 8,840.00
货期*
5周
规格
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经常一起买 (4)
Rabbit polyclonal antibody to Scaffold attachment factor B1 (scaffold attachment factor B)
CNY 6,281.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | HAP; HET; SAB-B1; SAF-B; SAF-B1; SAFB1 |
Vector | pCMV6-Entry |
Sequence Data |
>SC331410 representing NM_001201338.
Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGCGGAGACTCTGTCAGGCCTAGGTGATTCTGGAGCGGCGGGCGCGGCGGCTCTGAGCTCCGCCTCG TCAGAGACCGGGACGCGGCGCCTCAGCGACCTGCGAGTGATCGATCTGCGGGCGGAGCTGAGGAAACGG AATGTGGACTCGAGCGGCAACAAGAGCGTTTTGATGGAGCGGCTGAAGAAGGCAATTGAAGATGAAGGT GGTAATCCTGACGAAATTGAAATTACCTCCGAGGGAAACAAGAAAACATCAAAGAGGTCTAGCAAAGGG CGCAAACCAGAAGAAGAGGGTGTGGAAGATAACGGGCTGGAGGAAAACTCTGGGGATGGACAGGAGGAT GTTGAGACCAGTCTGGAGAACTTGCAGGACATCGACATCATGGATATCAGTGTGTTGGATGAAGCAGAA ATTGATAATGGAAGCGTTGCAGATTGTGTCGAAGACGATGATGCTGATAACCTCCAGGAGTCCCTGTCG GATAGTAGAGAGCTAGTCGAGGGGGAAATGAAAGAGCTTCCGGAGCAGCTTCAGGAACATGCTATAGAG GACAAAGAAACTATAAACAATTTAGATACTTCATCATCTGACTTCACTATATTACAGGAAATTGAAGAG CCATCCCTGGAGCCAGAAAATGAGAAAATACTCGACATTTTGGGGGAAACTTGTAAATCTGAGCCAGTA AAAGAAGAAAGTTCCGAGCTGGAGCAGCCATTTGCACAGGACACAAGTAGCGTGGGGCCAGACAGAAAG CTTGCGGAGGAAGAGGACCTATTTGACAGCGCCCATCCGGAAGAGGGTGATTTAGATTTGGCCAGCGAG TCAACAGCACACGCTCAGTCGAGCAAGGCAGACAGCCTGTTAGCGGTAGTGAAAAGGGAGCCCGCGGAG CAGCCAGGCGATGGCGAGAGGACGGACTGTGAGCCTGTAGGGCTAGAGCCGGCAGTTGAGCAGAGTAGT GCGGCCTCCGAGCTCGCGGAGGCCTCTAGCGAGGAGCTCGCAGAAGCACCCACGGAAGCCCCAAGCCCA GAAGCCAGAGATAGCAAAGAAGACGGGAGGAAGTTTGATTTTGACGCTTGTAATGAAGTCCCTCCGGCT CCTAAAGAGTCCTCAACCAGTGAGGGCGCTGATCAGAAAATGAGTTCTCCCGAAGATGACTCGGATACA AAAAGGCTTTCCAAAGAGGAAAAGGGTCGCAGCAGTTGTGGTAGAAATTTCTGGGTTAGTGGACTCTCT TCTACAACCAGAGCTACAGATTTGAAGAATCTTTTCAGCAAATATGGGAAGGTGGTGGGCGCCAAGGTT GTGACAAATGCCCGGAGTCCTGGAGCTCGCTGTTACGGTTTTGTCACGATGTCCACAGCAGAAGAGGCC ACAAAATGCATTAACCACCTGCACAAGACGGAGCTCCACGGAAAGATGATCTCCGTGGAGAAAGCCAAA AATGAACCTGTGGGAAAGAAAACCTCTGACAAAAGAGACAGTGACGGGAAAAAGGAGAAGTCGAGCAAC AGTGACAGATCTACAAACCTTAAGAGGGATGATAAATGTGACAGAAAAGATGATGCTAAGAAGGGTGAC GACGGAAGTGGAGAAAAGAGTAAGGACCAAGATGATCAGAAACCTGGCCCCTCAGAGCGATCTCGAGCC ACAAAGTCAGGAAGTCGAGGGACCGAACGGACTGTAGTAATGGATAAATCCAAAGGGGTGCCTGTGATT AGTGTAAAAACGTCCGGGTCCAAAGAGAGAGCTTCCAAAAGCCAGGATCGCAAATCAGCCAGCAGAGAG AAGCGGTCCGTCGTGTCCTTTGATAAGGTCAAGGAGCCTCGGAAGTCAAGAGACTCAGAGTCCCATAGC AGGGTGCGTGAACGCAGTGAACGCGAACAACGCATGCAGGCGCAGTGGGAGCGCGAGGAGCGTGAGCGG CTGGAGATTGCCCGAGAGAGGCTGGCCTTCCAGCGCCAGCGGCTGGAGCGGGAGCGCATGGAGCGGGAA CGGCTGGAGCGCGAACGCATGCACGTGGAGCACGAGCGCAGGCGCGAGCAGGAGCGCATCCACCGTGAG CGCGAGGAGCTGAGGCGCCAGCAGGAACTGCGCTATGAGCAGGAGCGGCGGCCCGCGGTGCGGCGGCCC TACGACCTGGACCGGCGAGATGATGCCTATTGGCCGGAAGCCAAGCGGGCCGCCCTGGATGAGCGCTAC CATTCTGACTTTAACCGCCAGGACCGCTTCCACGACTTTGACCACAGGGACCGCGGCCGCTACCCCGAC CACTCGGTGGACAGGAGAGAAGGTTCAAGGTCAATGATGGGAGAACGAGAAGGACAGCATTACCCAGAA CGCCATGGAGGACCAGAGCGCCACGGCCGGGACTCCCGCGATGGCTGGGGGGGCTATGGCTCTGACAAG AGGATGAGCGAGGGCCGGGGGCTGCCTCCTCCCCCCAGGGGCAGACGTGACTGGGGGGACCATGGCCGA AGAGAGGATGACCGGTCATGGCAGGGCACGGCCGACGGGGGCATGATGGACAGGGATCACAAGAGGTGG CAAGGTGGCGAGAGAAGCATGTCCGGTCACTCCGGGCCTGGCCACATGATGAACCGAGGAGGAATGTCA GGGCGCGGCAGCTTTGCCCCAGGCGGGGCCTCCCGGGGCCACCCCATCCCACACGGTGGCATGCAGGGC GGGTTTGGAGGCCAGAGCCGGGGGAGCAGGCCCAGCGATGCCCGCTTCACTCGCCGCTACTGA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001201338 |
Insert Size | 2754 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001201338.1 |
RefSeq Size | 3121 bp |
RefSeq ORF | 2754 bp |
Locus ID | 6294 |
UniProt ID | Q15424 |
Protein Families | Druggable Genome, Transcription Factors |
MW | 102.9 kDa |
Gene Summary | This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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