SUN2 (NM_001199579) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	UNC84B
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331327 representing NM_001199579. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGTCCCGAAGAAGCCAGCGCCTCACGCGCTACTCCCAGGGTGACGATGACGGCAGCAGCAGCAGCGGA GGGAGCTCGGTGGCTGGGAGTCAGAGCACCCTGTTTAAAGACAGTCCTCTCAGGACCTTGAAGAGGAAA TCCAGCAACATGAAGCGCCTGTCCCCAGCGCCACAGCTGGGCCCGTCCTCTGATGCACACACCTCCTAC TACAGTGAGTCGCTGGTCCACGAGTCCTGGTTCCCACCCAGGAGCTCCCTGGAGGAACTGCATGGTGAC GCCAACTGGGGTGAGGACCTGCGGGTGCGGAGGAGGAGAGGCACGGGTGGCTCAGAGAGCAGCAGGGCC AGCGGGCTTGTGGGGCGCAAGGCCACCGAGGACTTCCTGGGCTCTTCCTCGGGCTACTCCTCTGAGGAC GACTACGTGGAAGACAGTGAAGGAAGAGGCTCGAAAGTGACAGAGACTGAGCCAGTGTCCTCGTTCCCC GCAGGCTACTCGGATGTGGACCAGCAGAGTTCCAGCTCGCGGCTCCGAAGCGCCGTCTCACGGGCGGGC TCCTTACTCTGGATGGTGGCCACTTCGCCAGGCCGGCTCTTCAGACTTCTCTACTGGTGGGCTGGCACC ACCTGGTACCGCCTGACCACAGCTGCCTCCCTCCTTGACGTCTTCGTTTTAACCAGGCGCTTCTCGTCC CTGAAGACGTTCCTCTGGTTCCTGCTGCCGCTGCTCTTGCTGACGTGCCTGACGTATGGTGCTTGGTAT TTCTACCCCTATGGGCTGCAGACATTCCACCCTGCTTTGGTTTCCTGGTGGGCAGCGAAGGACAGCAGG AGGCCGGATGAGGGCTGGGAAGCCAGAGACTCATCGCCACATTTCCAGGCTGAGCAGCGTGTTATGTCC CGGGTACACTCTCTGGAGCGGCGTCTGGAAGCTCTTGCTGCTGAATTTTCCTCCAACTGGCAGAAGGAG GCCATGCGGCTGGAACGTCTGGAGCTGCGGCAAGGGGCTCCTGGCCAGGGAGGTGGTGGTGGCCTGAGC CACGAGGACACCCTGGCGCTGCTGGAGGGGCTAGTGAGCCGCCGTGAAGCTGCCCTGAAGGAGGATTTC CGCAGGGAAACTGCTGCTCGCATCCAGGAAGAACTGTCTGCCCTGAGAGCAGAGCATCAGCAAGACTCA GAAGACCTCTTCAAGAAGATCGTCCGGGCCTCCCAGGAGTCCGAGGCTCGCATCCAGCAGCTGAAGTCA GAGTGGCAAAGCATGACCCAGGAGTCCTTCCAGGAGAGCTCTGTGAAGGAGCTGAGGCGGCTGGAGGAC CAGCTGGCCGGCCTGCAGCAGGAGCTGGCGGCTCTGGCACTGAAGCAGAGCTCGGTGGCGGAAGAAGTG GGCCTGCTGCCCCAGCAGATCCAGGCCGTGCGGGACGACGTGGAATCTCAGTTCCCGGCCTGGATCAGT CAGTTCCTTGCCCGAGGTGGAGGGGGCCGCGTGGGGCTCCTTCAGAGAGAGGAGATGCAAGCTCAGCTG CGAGAGCTGGAGAGCAAGATCCTCACCCATGTGGCAGAGATGCAGGGCAAGTCGGCCAGGGAAGCCGCG GCCTCCCTGAGCCTGACGCTGCAGAAAGAAGGTGTGATTGGAGTGACAGAGGAGCAGGTGCACCACATC GTGAAGCAGGCCCTGCAGCGCTACAGTGAGGACCGCATCGGGCTGGCAGACTACGCCCTGGAGTCAGGA GGGGCCAGCGTCATCAGCACCCGATGTTCTGAGACCTACGAGACCAAGACGGCCCTCCTCAGCCTCTTC GGCATCCCCCTGTGGTACCACTCCCAGTCACCCCGAGTCATCCTCCAGCCAGATGTGCACCCAGGCAAC TGCTGGGCCTTCCAGGGGCCACAAGGCTTCGCCGTGGTCCGCCTCTCTGCCCGCATCCGCCCCACAGCC GTTACCTTAGAGCATGTGCCCAAGGCCTTGTCACCCAACAGCACTATCTCCAGTGCCCCCAAGGACTTC GCCATCTTTGGGTTTGACGAAGACCTGCAGCAGGAGGGGACACTCCTTGGCAAGTTCACTTACGATCAG GACGGCGAGCCTATTCAGACGTTTCACTTTCAGGCCCCTACGATGGCCACGTACCAGGTGGTGGAGCTG CGGATCCTGACTAACTGGGGCCACCCCGAGTACACCTGCATCTACCGCTTCAGAGTGCATGGGGAGCCC GCCCACTAG
Restriction Sites	SgfI-MluI
ACCN	NM_001199579
Insert Size	2217 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001199579.1
RefSeq Size	4070 bp
RefSeq ORF	2217 bp
Locus ID	25777
UniProt ID	Q9UH99
Protein Families	Transmembrane
MW	82.5 kDa
Gene Summary	SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.