CAIN (CABIN1) (NM_001199281) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	CAIN; KB-318B8.7; PPP3IN
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331289 representing NM_001199281. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGAAGGAAGCTTTAAAAGT CACAAAACCCAGACAAAGGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTG CAGAAACATGACCGGTTTGAGGAGTCTGCCAAAGCCTACCATGAGCTCTTGGAGGCGAGCCTGCTGCGG GAGGCAGTTTCATCCGGTGATGAGAAAGAGGGGTTGAAACACCCTGGGCTGATACTGAAATATTCCACT TATAAGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGACAGCCATGGAGTTCTACTTAGAG GCAGTGATGCTGGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCATC CGGATCCCCCTGGCTCGCCATGCTTTTGAGGAAGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTG GATAACCTAATCACTGTCCTGTACACCCTCAGTGATTACACAACATGTCTGTACTTCATCTGCAAAGCT TTGGAGAAGGATTGCCGGTACAGCAAAGGGCTGGTCCTCAAGGAGAAGATTTTTGAGGAGCAGCCTTGT CTCCGGAAGGACTCTCTCAGAATGTTCCTCAAATGTGACATGTCGATTCACGATGTTTCGGTGAGTGCA GCTGAGACACAGGCGATTGTAGATGAGGCCTTGGGGCTGCGAAAAAAGAGGCAAGCGCTGATTGTGCGG GAGAAGGAGCCGGACCTGAAACTTGTGCAGCCCATTCCTTTCTTCACCTGGAAGTGCCTCGGAGAGAGC TTGCTGGCCATGTACAATCATCTCACCACCTGTGAGCCCCCACGTCCCAGCCTTGGCAAAAGGATTGAT TTGTCGGACTACCAGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCCAGTTAACGTGATC CAGCCAAGCACTGTCAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTG GCTACAACCAGCTTCCCACTGCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCT GGGGGAGATAAATCCAAGAAAGGGGTAAAACGGAAGAAGATTTCAGAAGAGAGTGGAGAAACAGCAAAG CGGCGGTCTGCCCGTGTCCGAAACACCAAGTGCAAAAAAGAAGAGAAAGTAGACTTCCAGGAGCTTCTG ATGAAGTTCTTGCCGTCCAGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTAT GAAGTCCAGTCAGAAGCCAAACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCA GCCACATTCATGGAATCTGAAAAGCAGGACGTGCATGAGTTCCTGCTGGAGAACCTAACCAACGGGGGC ATCCTGGAGCTGATGATGCGCTACCTGAAAGCCATGGGCCACAAGTTCTTGGTAAGGTGGCCTCCAGGC TTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCCGCTG CTGAGGGACTGCAGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAG CTGGACCAGTGGCTGCTGACCAAAGGCAGAAGCTCTGCAGTGTCTCCTCGGAACTGCCCTGCTGGTATG GTGAATGGCAGATTTGGACCTGACTTCCCAGGGACCCACTGCCTGGGTGACCTCCTACAGCTGTCATTT GCCTCGTCCCAGCGCGACCTGTTCGAGGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTACTGGCTGAAG GCTCGCTTCCTGGCGCTGCAGGGAGACATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATG CTCCAGAGTTCCACCGCCATCCAGGTGGAGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCC AACCTCCATAATGACTCTGTGGTTTCCCTGGAGGAGATTGATAAGAACCTGAAGTCGCTGGAGCGGTGC CAGTCCCTGGAGGAGATTCAGCGGCTGTATGAAGCAGGCGACTACAAGGCTGTTGTGCATCTGCTCCGC CCCACTTTGTGCACCAGTGGGTTTGACCGGGCCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGG CCAGCCCAGCTGCTTCTTCTGCAGGACTCCTTGCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGT TCCGATGTGGCTCTGAACGAGGCTGTCCAGCAGATGGTGAACTCAGGTGAGGCTGCCGCCAAGGAGGAG TGGGTGGCCACAGTGACCCAACTGCTGATGGGCATCGAGCAGGCCCTCTCTGCGGACAGCAGTGGTAGC ATCCTGAAGGTATCATCCTCCACCACTGGCCTTGTGCGGCTCACCAACAACCTCATCCAGGTCATTGAC TGCAGCATGGCTGTGCAGGAGGAGGCCAAGGAGCCCCACGTCTCTTCAGTGCTACCCTGGATCATTCTA CACCGGATCATCTGGCAGGAGGAAGACACCTTCCATTCTCTGTGCCACCAGCAGCAGCTCCAAAACCCA GCGGAGGAAGGGATGTCAGAGACGCCCATGCTCCCATCCTCCCTCATGCTGCTGAACACAGCCCACGAG TATTTGGGCAGAAGGTCCTGGTGCTGCAATTCAGATGGGGCTCTGCTGCGATTCTATGTGCGAGTACTC CAGAAGGAACTGGCTGCATCCACCTCTGAAGACACGCACCCTTACAAGGAGGAGCTGGAGACAGCCTTG GAGCAGTGCTTCTACTGCCTGTACAGCTTCCCCAGCAAGAAGAGTAAGGCCAGGTACCTGGAGGAACAC TCGGCCCAGCAGGTGGATCTTATATGGGAGGATGCACTGTTCATGTTTGAGTATTTTAAGCCCAAGACC CTTCCTGAATTTGACAGCTATAAGACCAGCACCGTGTCTGCTGACTTGGCCAACCTACTGAAGAGAATT GCCACCATTGTGCCTCGCACAGAGAGGCCAGCCCTTAGCCTGGACAAAGTCTCTGCCTACATTGAGGGA ACTTCAACTGAGGTACCCTGCCTCCCAGAGGGGGCTGACCCCTCCCCTCCAGTGGTGAACGAGCTTTAC TACCTCCTGGCTGATTATCATTTCAAAAACAAGGAGCAGTCCAAGGCCATCAAGTTCTACATGCATGAC ATCTGCATCTGCCCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCTGGCCCGGGCCAGCCGCATTCAG GACAAGCTGAACTCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAGCATGCCACGCCCGTCTTGAAC TGCTTCCGTCGGGCCCTGGAGATTGACAGCTCCAACTTGTCCCTATGGATTGAGTATGGCACCATGTCC TATGCCTTGCACTCATTCGCCTCACGTCAATTGAAGCAGTGGAGAGGCGAGCTGCCCCCTGAGCTCGTG CAGCAGATGGAGGGCCGGCGCGACAGCATGCTAGAGACAGCCAAGCACTGTTTCACATCAGCAGCCCGC TGCGAGGGTGATGGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGGCTGAGAAGCAG CAGCAGCCACCCACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCTGCACGAGGAGGCTGCC CGCTACCCCAAGAAGATCCACTACCACAACCCACCTGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTT CGGCTCCATGCTTCCATCCTGAAGCTCCTGGGGAAGCCCGATTCTGGGGTTGGTGCAGAGGTCCTGGTC AACTTTATGAAGGAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACACACCCAAAGCTTCA GAAAAGGAGAAGGCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGA GCCTCCCTCCCCTCCTCCTCTGGCCCAGGTCTGACATCCCCACCTTACACAGCCACTCCGATTGACCAC GATTACGTCAAATGTAAAAAACCCCACCAGCAGGCAACGCCGGACGACCGAAGCCAGGACAGCACAGCC GTAGCACTCTCAGACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAGCTTACTGGAAGGCTCC AGGAAATCCTACACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTAAAGATCTT CAGGGGGCCACAGAAGAAAGAGGAAAAAACGAGGAGTCATTGGAGAGTACAGAAGGCTTCCGGGCTGCA GAGCAAGGTGTCCAGAAGCCTGCTGCAGAAACCCCAGCCTCTGCTTGCATCCCTGGCAAGCCCTCAGCA TCCACACCCACCCTGTGGGATGGGAAGAAGAGAGGGGACCTCCCAGGGGAGCCAGTGGCCTTCCCCCAG GGGCTGCCGGCTGGTGCTGAGGAGCAGCGGCAGTTTCTCACAGAGCAGTGCATCGCCTCCTTCCGCCTG TGCCTGAGCCGCTTCCCCCAGCACTATAAGAGTCTCTACCGTCTGGCCTTCCTCTACACCTACAGCAAG ACCCACCGGAACCTCCAGTGGGCCCGCGACGTGTTGCTAGGCAGCAGTATCCCGTGGCAACAACTGCAG CACATGCCGGCACAGGGGCTCTTCTGCGAGAGGAACAAGACCAATTTCTTCAACGGCATCTGGCGGATC CCCGTGGACGAGATTGACCGGCCGGGCAGCTTTGCCTGGCACATGAACCGCTCCATCGTGCTGCTGCTC AAGGTGCTGGCCCAGCTGCGGGACCACAGCACCCTGCTGAAGGTGTCCTCCATGCTTCAGCGGACCCCA GACCAGGGCAAGAAGTATCTGCGAGATGCTGACCGCCAGGTCCTGGCGCAGCGGGCCTTCATCCTCACT GTGAAGGTGCTCGAAGACACGCTGAGCGAGCTCGCAGAGGGGTCAGAACGCCCAGGGCCCAAGGTCTGT GGCCTCCCCGGAGCCAGGATGACCACCGATGTCTCACACAAGGCCAGTCCTGAGGATGGCCAGGAGGGC CTCCCCCAGCCGAAGAAGCCCCCTCTGGCTGATGGCTCAGGGCCAGGGCCCGAGCCAGGAGGCAAAGTG GGCCTCCTCAACCACCGGCCTGTGGCCATGGATGCAGGAGACAGTGCAGACCAAAGCGGGGAGCGGAAG GATAAAGAGAGCCCACGGGCAGGGCCCACTGAGCCCATGGACACGAGTGAGGCCACTGTTTGCCACTCA GACTTGGAGCGGACACCACCCCTGCTGCCAGGTCGCCCCGCAAGGGACCGGGGCCCCGAGAGCCGGCCC ACTGAGCTGTCCCTGGAGGAGCTGAGCATCAGTGCCCGGCAGCAGCCCACCCCGCTCACCCCAGCCCAG CCAGCCCCCGCCCCCGCCCCCGCCACCACCACAGGGACCAGGGCAGGGGGCCACCCGGAGGAGCCGCTC TCCCGGCTCAGCCGCAAGAGGAAGCTCCTGGAGGACACAGAGTCAGGCAAGACACTTCTGTTGGATGCC TACCGTGTGTGGCAGCAGGGCCAGAAGGGTGTGGCCTATGACCTGGGCCGTGTGGAGAGGATCATGTCG GAGACCTACATGCTCATCAAGCAGGTGGATGAGGAGGCTGCGCTGGAGCAGGCTGTGAAGTTCTGCCAG GTCCATCTTGGGGCTGCCGCCCAGAGACAGGCCTCGGGGGACACCCCCACCACTCCAAAGCACCCCAAA GACAGCCGAGAGAACTTCTTTCCTGTGACAGTGGTGCCCACAGCCCCTGACCCTGTGCCAGCTGACTCT GTCCAGCGGCCCAGTGATGCTCACACCAAGCCTCGCCCTGCACTAGCTGCCGCCACAACTATTATCACC TGCCCTCCGTCAGCATCAGCTTCCACCCTGGACCAGTCCAAGGACCCTGGGCCTCCCCGGCCACACAGG CCTGAAGCTACCCCCAGCATGGCCTCTCTGGGCCCAGAGGGAGAAGAGCTGGCGAGAGTGGCAGAGGGC ACCAGCTTCCCGCCTCAGGAGCCACGGCACAGTCCGCAGGTGAAGATGGCCCCCACAAGTTCCCCGGCA GAGCCACACTGCTGGCCGGCAGAGGCTGCCCTGGGCACAGGCGCTGAGCCCACCTGCAGCCAGGAGGGG AAACTGAGGCCTGAGCCGAGAAGGGATGGGGAGGCTCAGGAGGCTGCGAGTGAGACTCAGCCCCTGAGC TCTCCCCCAACAGCTGCCAGCTCCAAGGCCCCCAGCAGTGGGAGTGCCCAGCCACCAGAGGGTCACCCA GGCAAGCCTGAGCCCAGCCGGGCTAAGTCCCGCCCCCTGCCCAACATGCCAAAGCTGGTCATCCCCTCC GCCGCCACCAAGTTCCCCCCTGAGATCACCGTCACGCCACCCACCCCAACCCTGCTCTCCCCCAAAGGC AGCATCTCGGAGGAGACCAAGCAGAAGCTGAAGTCAGCCATCCTTTCTGCCCAGTCTGCTGCCAACGTG AGGAAGGAGAGCCTATGCCAGCCAGCCCTGGAGGTCCTGGAGACATCCAGCCAGGAGTCCTCGCTGGAG AGCGAGACAGACGAGGACGACGACTACATGGACATTTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001199281
Insert Size	6663 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001199281.1
RefSeq Size	7528 bp
RefSeq ORF	6663 bp
Locus ID	23523
UniProt ID	Q9Y6J0
Protein Families	Druggable Genome
MW	246.4 kDa
Gene Summary	Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Both variants 1 and 2 encode the same isoform (a).

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