ADCY4 (NM_001198592) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	AC4
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331206 representing NM_001198592. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGCCCGCCTCTTCAGCCCCCGGCCGCCCCCCAGCGAAGACCTCTTCTACGAGACCTACTACAGCCTG AGCCAGCAGTACCCGCTGCTGCTGCTGCTGCTGGGGATCGTGCTCTGTGCGCTCGCGGCGCTGCTCGCA GTGGCCTGGGCCAGCGGCAGGGAGCTGACCTCAGACCCGAGCTTCCTGACCACTGTGCTGTGCGCGCTG GGCGGCTTCTCGCTGCTGCTGGGCCTCGCTTCCCGGGAGCAGCGACTGCAGCGCTGGACGCGTCCCCTG TCCGGCTTGGTATGGGTCGCGCTGCTAGCGCTAGGCCACGCCTTCCTGTTCACCGGGGGCGTGGTGAGC GCCTGGGACCAGGTGTCCTATTTTCTCTTCGTCATCTTCACGGCGTATGCCATGCTGCCCTTGGGCATG CGGGACGCCGCCGTCGCGGGCCTCGCCTCCTCACTCTCGCATCTGCTGGTCCTCGGGCTGTATCTTGGG CCACAGCCGGACTCACGGCCTGCACTGCTGCCGCAGTTGGCAGCAAACGCAGTGCTGTTCCTGTGCGGG AACGTGGCAGGAGTGTACCACAAGGCGCTGATGGAGCGCGCCCTGCGGGCCACGTTCCGGGAGGCACTC AGCTCCCTGCACTCACGCCGGCGGCTGGACACCGAGAAGAAGCACCAGGAACACCTTCTCTTGTCCATC CTTCCTGCCTACCTGGCCCGAGAGATGAAGGCAGAGATCATGGCACGGCTGCAGGCAGGACAGGGGTCA CGGCCAGAGAGCACTAACAATTTCCACAGCCTCTATGTCAAGAGGCACCAGGGAGTCAGCGTGCTGTAT GCTGACATCGTGGGCTTCACGCGGCTGGCCAGCGAGTGTTCCCCTAAGGAGCTGGTGCTCATGCTCAAT GAGCTCTTTGGCAAGTTCGACCAGATTGCCAAGGAGCATGAATGCATGCGGATCAAGATCCTGGGGGAC TGTTACTACTGTGTCTCTGGGCTGCCACTCTCACTGCCAGACCATGCCATCAACTGCGTGCGCATGGGC CTGGACATGTGCCGGGCCATCAGGAAACTGCGGGCAGCCACTGGCGTGGACATCAACATGCGTGTGGGC GTGCACTCAGGCAGCGTACTGTGTGGAGTCATCGGGCTGCAGAAGTGGCAGTACGACGTTTGGTCACAT GATGTCACACTGGCTAACCACATGGAGGCAGGCGGTGTACCAGGGCGAGTGCACATCACAGGGGCTACC CTGGCCCTGCTGGCAGGGGCTTATGCTGTGGAGGACGCAGGCATGGAGCATCGGGACCCCTACCTTCGG GAGCTAGGGGAGCCTACCTATCTGGTCATCGATCCACGGGCAGAGGAGGAGGATGAGAAGGGCACTGCA GGAGGCTTGCTGTCCTCGCTTGAGGGCCTCAAGATGCGTCCATCACTGCTGATGACCCGTTACCTGGAG TCCTGGGGCGCAGCCAAGCCTTTTGCCCACCTGAGCCACGGAGACAGCCCTGTGTCCACCTCCACCCCT CTCCCGGAGAAGACCCTGGCTTCCTTCAGCACCCAGTGGAGCCTGGATCGGAGCCGTACCCCCCGGGGA CTAGATGATGAACTGGACACCGGGGATGCCAAGTTCTTCCAGGTCATTGAGCAGCTCAACTCGCAGAAA CAGTGGAAGCAGTCGAAGGACTTCAACCCACTGACACTGTACTTCAGAGAGAAGGAGATGGAGAAAGAG TACCGACTCTCTGCAATCCCCGCCTTCAAATACTATGAAGCCTGCACCTTCCTGGTTTTTCTCTCCAAC TTCATCATCCAGATGCTAGTGACAAACAGGCCCCCAGCTCTGGCCATCACGTATAGCATCACCTTCCTC CTCTTCCTCCTCATCCTTTTTGTCTGCTTCTCAGAGGACCTGATGAGGTGTGTCCTGAAAGGCCCCAAG ATGCTGCACTGGCTGCCTGCACTGTCTGGCCTGGTGGCCACACGACCAGGACTGAGAATAGCCTTGGGC ACCGCCACCATCCTCCTTGTCTTTGCCATGGCCATTACCAGCCTGTTCTTCTTCCCAACATCATCAGAC TGCCCTTTCCAAGCTCCCAATGTGTCCTCCATGATTTCCAACCTCTCCTGGGAGCTCCCTGGGTCTCTG CCTCTCATCAGTGTCCCATACTCCATGCACTGCTGCACGCTGGGCTTCCTCTCCTGCTCCCTCTTTCTG CACATGAGCTTCGAGCTGAAGCTGCTGCTGCTCCTGCTGTGGCTGGCGGCATCCTGCTCCCTCTTCCTG CACTCCCATGCCTGGCTGTCGGAATGCCTCATCGTCCGCCTCTATCTGGGCCCCTTGGACTCCAGGCCC GGAGTGCTGAAGGAGCCCAAACTGATGGGTGCTATCTCCTTCTTCATCTTCTTCTTCACCCTCCTTGTC CTGGCTCGCCAGAATGAGTACTACTGCCGCCTGGACTTCCTGTGGAAGAAGAAGCTGAGGCAGGAGAGG GAGGAGACAGAGACGATGGAGAACCTGACTCGGCTGCTCTTGGAGAACGTGCTCCCTGCACACGTGGCC CCCCAGTTCATTGGCCAGAACCGGCGCAACGAGGATCTCTACCACCAGTCCTATGAATGCGTTTGTGTC CTCTTCGCCTCAGTCCCAGACTTCAAGGAGTTCTACTCTGAATCCAACATCAATCATGAGGGCCTAGAG TGTCTGAGGCTGCTCAATGAGATAATTGCTGATTTTGATGAGCTGCTCTCCAAGCCCAAGTTCAGTGGG GTGGAGAAGATCAAGACCATCGGCAGCACCTACATGGCAGCCACAGGCTTAAATGCCACCTCTGGACAG GATGCACAACAGGATGCTGAACGGAGCTGCAGCCACCTTGGCACTATGGTGGAATTTGCCGTGGCCCTG GGGTCTAAGCTGGACGTCATCAACAAGCATTCATTCAACAACTTCCGCCTGCGAGTGGGGTTGAACCAT GGACCCGTAGTAGCTGGAGTTATTGGGGCCCAGAAGCCGCAATATGACATTTGGGGCAACACAGTGAAC GTGGCCAGCCGCATGGAGAGTACAGGAGTCCTTGGCAAAATCCAAGTGACTGAGGAGACAGCATGGGCC CTACAGTCCCTGGGCTACACCTGCTACAGCCGGGGTGTCATCAAGGTGAAAGGCAAAGGGCAGCTCTGC ACCTACTTCCTGAACACAGACTTGACACGAACTGGACCTCCTTCAGCTACCCTAGGCTGA
Restriction Sites	SgfI-RsrII
ACCN	NM_001198592
Insert Size	3234 bp
OTI Disclaimer	Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001198592.1
RefSeq Size	3419 bp
RefSeq ORF	3234 bp
Locus ID	196883
UniProt ID	Q8NFM4
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Calcium signaling pathway, Chemokine signaling pathway, Dilated cardiomyopathy, Gap junction, GnRH signaling pathway, Melanogenesis, Oocyte meiosis, Progesterone-mediated oocyte maturation, Purine metabolism, Taste transduction, Vascular smooth muscle contraction
MW	119.8 kDa
Gene Summary	This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010] Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.

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