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NALP2 (NLRP2) (NM_001174083) Human Untagged Clone
CAT＃: SC329265
NLRP2 (untagged)-Human NLR family pyrin domain containing 2 (NLRP2) transcript variant 4
CNY 20,050.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CLR19.9; NALP2; NBS1; PAN1; PYPAF2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001174083, the custom clone sequence may differ by one or more nucleotides
ATGGTGTCTTCGGCGCAGATGGGCTTCAACCTGCAGGCTCTCCTGGAGCAGCTCAGCCAG GATGAGTTGAGCAAGTTCAAGTATCTGATCACGACCTTCTCCCTGGCACACGAGCTCCAG AAGATCCCCCACAAGGAGATGGCGAGCCTCCAGGTCTTTGAAAAGATGCACCGAATGGAT CTGTCTGAGAGAGCAAAGGATGAAGTCAGAGAAGCAGCTTTGAAATCCTTTAATAAAAGG AAGCCTCTATCATTAGGGATAACACGGAAAGAACGACCACCTCTAGACGTGGACGAAATG CTGGAGCGCTTCAAAACAGAAGCACAAGCGTTTACAGAAACGAAAGGAAATGTCATCTGC CTGGGTAAAGAAGTCTTTAAAGGAAAAAAGCCAGACAAAGACAATAGGTGCAGGTATATA TTGAAGACGAAGTTCCGGGAGATGTGGAAGAGCTGGCCTGGAGATAGCAAAGAGGTCCAG GTTATGGCTGAGAGATACAAGATGCTGATCCCATTCAGCAACCCCAGGGTGCTTCCCGGG CCCTTCTCATACACGGTGGTGCTGTATGGTCCTGCAGGCCTTGGGAAAACCACGCTGGCC CAGAAACTAATGCTAGACTGGGCAGAGGACAACCTCATCCACAAATTCAAATATGCGTTC TACCTCAGCTGCAGGGAGCTCAGCCGCCTGGGCCCGTGCAGTTTTGCAGAGCTGGTCTTC AGGGACTGGCCTGAATTGCAGGATGACATTCCACACATCCTAGCCCAAGCACGGAAAATC TTGTTCGTGATTGACGGCTTTGATGAGCTGGGAGCCGCACCTGGGGCGCTGATCGAGGAC ATCTGCGGGGACTGGGAGAAGAAGAAGCCGGTGCCCGTCCTCCTGGGGAGTTTGCTGAAC AGGGTGATGTTACCCAAGGCCGCCCTGCTGGTCACCACGCGGCCCAGGGCCCTGAGGGAC CTCCGGATCCTGGCGGAGGAGCCGATCTACATAAGGGTGGAGGGCTTCCTGGAGGAGGAC AGGAGGGCCTATTTCCTGAGACACTTTGGAGACGAGGACCAAGCCATGCGTGCCTTTGAG CTAATGAGGAGCAACGCGGCCCTGTTCCAGCTGGGCTCGGCCCCCGCGGTGTGCTGGATC GTGTGCACGACTCTGAAGCTGCAGATGGAGAAGGGGGAGGACCCGGTCCCCACCTGCCTC ACCCGCACGGGGCTGTTCCTGCGTTTCCTCTGCAGCCGGTTCCCGCAGGGCGCACAGCTG CGGGGCGCGCTGCGGACGCTGAGCCTCCTGGCCGCGCAGGGCCTGTGGGCGCAGACGTCC GTGCTTCACCGAGAGGATCTGGAAAGGCTCGGGGTGCAGGAGTCCGACCTCCGTCTGTTC CTGGACGGAGACATCCTCCGCCAGGACAGAGTCTCCAAAGGCTGCTACTCCTTCATCCAC CTCAGCTTCCAGCAGTTTCTCACTGCCCTGTTCTACACCCTGGAGAAGGAGGAGGAAGAG GATAGGGACGGCCACACCTGGGACATTGGGGACGTACAGAAGCTGCTTTCCGGAGTAGAA AGACTCAGGAACCCCGACCTGATCCAAGCAGGCTACTACTCCTTTGGCCTCGCTAACGAG AAGAGAGCCAAGGAGTTGGAGGCCACTTTTGGCTGCCGGATGTCACCGGACATCAAACAG GAATTGCTGCGATGCGACATAAGTTGTAAGGGTGGACATTCAACGGTGACAGACCTGCAG GAGCTCCTCGGCTGTCTGTACGAGTCTCAGGAGGAGGAGCTGGTGAAGGAGGTGATGGCT CAGTTCAAAGAAATATCCCTGCACTTAAATGCAGTAGACGTTGTGCCATCTTCATTCTGC GTCAAGCACTGTCGAAACCTGCAGAAAATGTCACTGCAGGTAATAAAGGAGAATCTCCCG GAGAATGTCACTGCGTCTGAATCAGACGCCGAGGTTGAGAGATCCCAGGATGATCAGCAC ATGCTTCCTTTCTGGACGGACCTTTGTTCCATATTTGGATCAAATAAGGATCTGATGGGT CTAGCAATCAATGATAGCTTTCTCAGTGCCTCCCTAGTAAGGATCCTGTGTGAACAAATA GCCTCTGACACCTGTCATCTCCAGAGAGTGGTGTTCAAAAACATTTCCCCAGCTGATGCT CATCGGAACCTCTGCCTAGCTCTTCGAGGTCACAAGACTGTAACGTATCTGACCCTTCAA GGCAATGACCAGGATGATATGTTTCCCGCATTGTGTGAGGTCTTGAGACATCCAGAATGT AACCTGCGATATCTCGGGTTGGTGTCTTGTTCCGCTACCACTCAGCAGTGGGCTGATCTC TCCTTGGCCCTTGAAGTCAACCAGTCCCTGACGTGCGTAAACCTCTCCGACAATGAGCTT CTGGATGAGGGTGCTAAGTTGCTGTACACAACTTTGAGACACCCCAAGTGCTTTCTGCAG AGGTTGTCGTTGGAAAACTGTCACCTTACAGAAGCCAATTGCAAGGACCTTGCTGCTGTG TTGGTTGTCAGCCGGGAGCTGACACACCTGTGCTTGGCCAAGAACCCCATTGGGAATACA GGGGTGAAGTTTCTGTGTGAGGGCTTGAGGTACCCCGAGTGTAAACTGCAGACCTTGGTG CTTTGGAACTGCGACATAACTAGCGATGGCTGCTGCGATCTCACAAAGCTTCTCCAAGAA AAATCAAGCCTGTTGTGTTTGGATCTGGGGCTGAATCACATAGGAGTTAAGGGAATGAAG TTCCTGTGTGAGGCTTTGAGGAAACCACTGTGCAACTTGAGATGTCTGTGGTTGTGGGGA TGTTCCATCCCTCCGTTCAGTTGTGAAGACCTCTGCTCTGCCCTCAGCTGCAACCAGAGC CTCGTCACTCTGGACCTGGGTCAGAATCCCTTGGGGTCTAGTGGAGTGAAGATGCTGTTT GAAACCTTGACATGTTCCAGTGGCACCCTCCGGACACTCAGGTTGAAAATCGATGACTTT AATGATGAACTCAATAAGCTGCTGGAAGAAATAGAAGAAAAAAACCCACAACTGATTATT GATACTGAGAAACATCATCCCTGGGCAGAAAGGCCTTCTTCTCATGACTTCATGATCTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_001174083 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001174083.1, NP_001167554.1 |
| RefSeq Size | 3521 bp |
| RefSeq ORF | 3120 bp |
| Locus ID | 55655 |
| UniProt ID | Q9NX02 |
| Gene Summary | This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016] Transcript Variant: This variant (4) lacks an in-frame exon in the CDS, as compared to variant 1. The resulting isoform (3) lacks an internal segment, as compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC230627 | NLRP2 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 4 |
CNY 10,360.00 |
|
| RC230627L3 | Lenti-ORF clone of NLRP2 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 4 |
CNY 12,260.00 |
|
| RC230627L4 | Lenti-ORF clone of NLRP2 (mGFP-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 4 |
CNY 12,260.00 |
|
| RG230627 | NLRP2 (tGFP-tagged) - Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 4 |
CNY 11,400.00 |
