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STAT2 (NM_198332) Human Untagged Clone
CAT＃: SC329176
STAT2 (untagged)-Human signal transducer and activator of transcription 2 113kDa (STAT2) transcript variant 2
CN¥ 16,440.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IMD44; ISGF-3; P113; PTORCH3; STAT113 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_198332, the custom clone sequence may differ by one or more nucleotides
ATGGCGCAGTGGGAAATGCTGCAGAATCTTGACAGCCCCTTTCAGGATCAGCTGCACCAG CTTTACTCGCACAGCCTCCTGCCTGTGGACATTCGACAGTACTTGGCTGTCTGGATTGAA GACCAGAACTGGCAGGAAGCTGCACTTGGGAGTGATGATTCCAAGGCTACCATGCTATTC TTCCACTTCTTGGATCAGCTGAACTATGAGTGTGGCCGTTGCAGCCAGGACCCAGAGTCC TTGTTGCTGCAGCACAATTTGCGGAAATTCTGCCGGGACATTCAGGATCCTACCCAGTTG GCTGAGATGATCTTTAACCTCCTTCTGGAAGAAAAAAGAATTTTGATCCAGGCTCAGAGG GCCCAATTGGAACAAGGAGAGCCAGTTCTCGAAACACCTGTGGAGAGCCAGCAACATGAG ATTGAATCCCGGATCCTGGATTTAAGGGCTATGATGGAGAAGCTGGTAAAATCCATCAGC CAACTGAAAGACCAGCAGGATGTCTTCTGCTTCCGATATAAGATCCAGGCCAAAGGGAAG ACACCCTCTCTGGACCCCCATCAGACCAAAGAGCAGAAGATTCTGCAGGAAACTCTCAAT GAACTGGACAAAAGGAGAAAGGAGGTGCTGGATGCCTCCAAAGCACTGCTAGGCCGATTA ACTACCCTAATCGAGCTACTGCTGCCAAAGTTGGAGGAGTGGAAGGCCCAGCAGCAAAAA GCCTGCATCAGAGCTCCCATTGACCACGGGTTGGAACAGCTGGAGACATGGTTCACAGCT GGAGCAAAGCTGTTGTTTCACCTGAGGCAGCTGCTGAAGGAGCTGAAGGGACTGAGTTGC CTGGTTAGCTATCAGGATGACCCTCTGACCAAAGGGGTGGACCTACGCAACGCCCAGGTC ACAGAGTTGCTACAGCGTCTGCTCCACAGAGCCTTTGTGGTAGAAACCCAGCCCTGCATG CCCCAAACTCCCCATCGACCCCTCATCCTCAAGACTGGCAGCAAGTTCACCGTCCGAACA AGGCTGCTGGTGAGACTCCAGGAAGGCAATGAGTCACTGACTGTGGAAGTCTCCATTGAC AGGAATCCTCCTCAATTACAAGGCTTCCGGAAGTTCAACATTCTGACTTCAAACCAGAAA ACTTTGACCCCCGAGAAGGGGCAGAGTCAGGGTTTGATTTGGGACTTTGGTTACCTGACT CTGGTGGAGCAACGTTCAGGTGGTTCAGGAAAGGGCAGCAATAAGGGGCCACTAGGTGTG ACAGAGGAACTGCACATCATCAGCTTCACGGTCAAATATACCTACCAGGGTCTGAAGCAG GAGCTGAAAACGGACACCCTCCCTGTGGTGATTATTTCCAACATGAACCAGCTCTCAATT GCCTGGGCTTCAGTTCTCTGGTTCAATTTGCTCAGCCCAAACCTTCAGAACCAGCAGTTC TTCTCCAACCCCCCCAAGGCCCCCTGGAGCTTGCTGGGCCCTGCTCTCAGTTGGCAGTTC TCCTCCTATGTTGGCCGAGGCCTCAACTCAGACCAGCTGAGCATGCTGAGAAACAAGCTG TTCGGGCAGAACTGTAGGACTGAGGATCCATTATTGTCCTGGGCTGACTTCACTAAGCGA GAGAGCCCTCCTGGCAAGTTACCATTCTGGACATGGCTGGACAAAATTCTGGAGTTGGTA CATGACCACCTGAAGGATCTCTGGAATGATGGACGCATCATGGGCTTTGTGAGTCGGAGC CAGGAGCGCCGGCTGCTGAAGAAGACCATGTCTGGCACCTTTCTACTGCGCTTCAGTGAA TCGTCAGAAGGGGGCATTACCTGCTCCTGGGTGGAGCACCAGGATGATGACAAGGTGCTC ATCTACTCTGTGCAACCGTACACGAAGGAGGTGCTGCAGTCACTCCCGCTGACTGAAATC ATCCGCCATTACCAGTTGCTCACTGAGGAGAATATACCTGAAAACCCACTGCGCTTCCTC TATCCCCGAATCCCCCGGGATGAAGCTTTTGGGTGCTACTACCAGGAGAAAGTTAATCTC CAGGAACGGAGGAAATACCTGAAACACAGGCTCATTGTGGTCTCTAATAGACAGGTGGAT GAACTGCAACAACCGCTGGAGCTTAAGCCAGAGCCAGAGCTGGAGTCATTAGAGCTGGAA CTAGGGCTGGTGCCAGAGCCAGAGCTCAGCCTGGACTTAGAGCCACTGCTGAAGGCAGGG CTGGATCTGGGGCCAGAGCTAGAGTCTGTGCTGGAGTCCACTCTGGAGCCTGTGATAGAG CCCACACTATGCATGGTATCACAAACAGTGCCAGAGCCAGACCAAGGACCTGTATCACAG CCAGTGCCAGAGCCAGATTTGCCCTGTGATCTGAGACATTTGAACACTGAGCCAATGGAA ATCTTCAGAAACTGTGTAAAGATTGAAGAAATCATGCCGAATGGTGACCCACTGTTGGCT GGCCAGAACACCGTGGATGAGGTTTACGTCTCCCGCCCCAGCCACTTCTACACTGATGGA CCCTTGATGCCTTCTGACTTCTAG |
| Restriction Sites | Please inquire |
| ACCN | NM_198332 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_198332.1, NP_938146.1 |
| RefSeq Size | 4564 bp |
| RefSeq ORF | 2544 bp |
| Locus ID | 6773 |
| UniProt ID | P52630 |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Chemokine signaling pathway, Jak-STAT signaling pathway |
| Gene Summary | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. The protein mediates innate antiviral activity. Mutations in this gene result in Immunodeficiency 44. [provided by RefSeq, Aug 2020] Transcript Variant: This variant (2) uses an alternate in-frame splice site, compared to variant 1. The resulting isoform (2) lacks an internal 4-aa segment, compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC230538 | STAT2 (Myc-DDK-tagged)-Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 2 |
CN¥ 7,130.00 |
|
| RC230538L3 | Lenti-ORF clone of STAT2 (Myc-DDK-tagged)-Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 2 |
CN¥ 9,030.00 |
|
| RC230538L4 | Lenti-ORF clone of STAT2 (mGFP-tagged)-Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 2 |
CN¥ 9,030.00 |
|
| RG230538 | STAT2 (tGFP-tagged) - Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 2 |
CN¥ 8,424.00 |
