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Sacsin (SACS) (NM_014363) Human Untagged Clone
CAT＃: SC328118
SACS (untagged)-Human spastic ataxia of Charlevoix-Saguenay (sacsin) (SACS)
CNY 88,160.00
货期*
详询
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARSACS; DNAJC29; PPP1R138; SPAX6 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_014363, the custom clone sequence may differ by one or more nucleotides
ATGGAGACCAAGGAGAACAGGTGGGTCCCGGTGACCGTGCTCCCCGGCTGCGTGGGCTGC AGGACCGTCGCGGCGCTGGCGTCCTGGACCGTGCGCGATGTGAAGGAACGTATCTTCGCG GAGACTGGCTTCCCGGTGTCGGAGCAGCGGCTGTGGCGCGGCGGCCGCGAGTTATCTGAC TGGATCAAGATTGGAGATCTGACTTCCAAAAATTGTCATCTTTTTGTAAACCTTCAATCA AAAGGCTTAAAAGGGGGAGGTCGATTTGGTCAGACAACGCCACCACTTGTTGATTTTCTC AAGGACATTTTGAGAAGATATCCAGAAGGAGGACAGATTCTTAAGGAATTAATTCAGAAT GCAGAAGATGCTGGGGCGACAGAAGTTAAATTTTTATATGATGAAACTCAATACGGAACA GAGACTCTTTGGTCAAAAGATATGGCGCCATATCAGGGGCCAGCTCTCTATGTGTACAAC AACGCGGTTTTCACCCCAGAGGACTGGCACGGCATTCAAGAAATAGCAAGAAGCAGGAAA AAGGATGATCCTCTGAAGGTCGGAAGATTTGGAATTGGGTTTAATTCTGTCTATCATATA ACAGATGTTCCTTGTATCTTTAGTGGTGACCAAATCGGGATGCTAGATCCTCATCAAACA CTTTTTGGCCCACATGAATCAGGCCAATGTTGGAATCTCAAAGATGACAGCAAAGAAATT AGTGAACTTTCAGACCAGTTTGCACCATTTGTTGGCATTTTTGGAAGCACCAAGGAAACA TTTATAAACGGCAATTTTCCAGGAACATTTTTCCGTTTCCCTCTTCGCCTACAACCTTCA CAACTTAGTAGTAACCTCTACAATAAGCAGAAGGTTCTTGAGTTGTTTGAGTCTTTTAGG GCAGATGCAGACACAGTGCTGCTCTTTCTGAAAAGTGTGCAGGATGTTTCCTTATATGTC CGAGAGGCTGACGGAACAGAGAAACTGGTGTTTAGAGTGACTTCGAGTGAGAGTAAGGCA CTGAAACATGAGCGGCCGAATTCTATAAAGATTCTGGGAACTGCTATAAGTAACTATTGT AAAAAGACTCCAAGCAATAACATCACCTGTGTAACATATCACGTAAATATTGTTTTAGAA GAGGAGAGTACTAAGGATGCACAGAAAACATCTTGGTTGGTGTGTAACAGTGTGGGTGGG CGAGGGATCAGTAGTAAGCTTGACTCTTTAGCTGATGAACTGAAATTTGTCCCAATCATT GGAATAGCCATGCCTTTATCAAGCAGAGATGATGAAGCAAAAGGAGCAACGTCTGATTTC TCAGGAAAAGCATTTTGTTTCCTTCCTTTACCACCTGGTGAGGAAAGCAGCACAGGCCTC CCAGTTCACATCAGTGGGTTCTTTGGCCTTACTGATAACCGCAGGAGCATAAAATGGAGA GAGCTGGACCAGTGGAGAGACCCGGCAGCCTTATGGAATGAGTTTCTTGTCATGAATGTT GTCCCCAAAGCTTATGCTACTCTGATCTTAGATTCAATAAAACGTCTGGAGATGGAAAAG AGCTCTGATTTCCCCTTGTCAGTTGATGTTATCTATAAGCTTTGGCCGGAGGCGAGCAAA GTCAAGGTGCACTGGCAACCGGTGTTAGAGCCTCTATTCAGCGAGCTGTTGCAGAATGCA GTGATTTATTCAATTAGCTGTGACTGGGTCAGGTTGGAGCAGGTGTACTTCTCAGAACTT GATGAAAATTTAGAATACACAAAAACTGTGCTCAACTACCTCCAGAGCTCAGGGAAGCAG ATTGCCAAGGTACCAGGGAATGTGGATGCTGCTGTTCAGCTCACAGCTGCCTCTGGCACA ACACCTGTGAGGAAGGTGACGCCCGCGTGGGTGCGGCAGGTGCTGCGGAAGTGTGCACAC CTGGGCTGTGCTGAAGAAAAGCTTCACCTTCTAGAATTTGTGCTTTCTGACCAAGCCTAC AGTGAGCTGCTTGGGCTGGAGCTGCTCCCTTTACAAAATGGCAATTTTGTCCCCTTCTCC TCATCTGTATCAGACCAAGATGTCATTTATATTACCTCAGCAGAATATCCAAGGTCCCTT TTCCCAAGTCTTGAAGGAAGATTTATTTTGGATAACTTGAAACCTCACCTTGTGGCTGCT TTAAAGGAAGCTGCCCAAACCCGAGGAAGACCATGTACTCAGCTGCAGCTTCTAAATCCA GAACGATTTGCACGTCTTATCAAGGAAGTAATGAATACATTCTGGCCTGGCAGAGAATTG ATTGTTCAATGGTATCCATTTGATGAAAACAGAAATCACCCATCTGTTTCATGGCTTAAG ATGGTTTGGAAAAATCTTTATATACATTTTTCAGAGGATTTGACTTTATTTGATGAGATG CCACTTATCCCCAGAACTATACTAGAGGAAGGTCAGACATGTGTGGAACTCATTAGACTC AGGATTCCATCGTTAGTCATTTTAGACGATGAATCTGAAGCACAGCTTCCAGAATTTTTA GCAGACATTGTACAAAAACTTGGAGGGTTTGTCCTTAAAAAATTAGATGCATCTATACAA CATCCGCTTATTAAAAAATATATTCATTCACCATTACCAAGTGCTGTTTTGCAGATAATG GAGAAGATGCCATTGCAGAAATTGTGTAATCAAATAACTTCGCTACTTCCAACACACAAA GATGCCCTGAGGAAGTTCTTGGCTAGTTTAACCGATAGCAGTGAGAAAGAGAAAAGAATT ATTCAAGAATTGGCAATATTCAAGCGCATTAACCATTCTTCTGATCAGGGAATTTCCTCT TATACAAAATTGAAAGGTTGTAAAGTCTTACACCATACTGCCAAACTCCCAGCAGATCTG CGACTTTCTATTTCAGTAATAGACAGTAGTGATGAAGCTACTATTCGTCTGGCAAACATG TTGAAAATAGAACAGTTAAAGACCACTAGCTGCTTAAAGCTTGTTTTAAAAGATATTGAA AATGCATTTTATTCACATGAAGAGGTAACACAGCTTATGTTATGGGTCCTTGAGAATCTA TCTTCTCTTAAAAATGAGAATCCAAATGTGCTTGAGTGGTTAACACCATTAAAATTCATC CAGATATCACAGGAACAGATGGTATCAGCTGGTGAACTCTTTGACCCTGATATAGAAGTA CTAAAGGATCTCTTTTGTAATGAAGAAGGAACCTATTTCCCACCCTCAGTTTTTACCTCA CCAGATATTCTTCACTCCTTAAGACAGATTGGTTTAAAAAACGAAGCCAGTCTCAAAGAA AAGGATGTTGTGCAAGTGGCAAAAAAAATTGAAGCCTTACAGGTCGGTGCTTGTCCTGAT CAAGATGTTCTTCTGAAGAAAGCCAAAACCCTCTTACTGGTTTTAAATAAGAATCACACA CTGTTGCAATCATCTGAAGGAAAGATGACATTGAAGAAAATAAAATGGGTTCCAGCCTGC AAGGAAAGGCCTCCAAATTATCCAGGCTCTTTGGTCTGGAAAGGAGATCTCTGTAATCTC TGTGCACCACCAGATATGTGTGATGTAGGCCATGCAATTCTCATTGGCTCCTCACTTCCT CTTGTTGAAAGTATCCATGTAAACCTGGAAAAAGCATTAGGGATCTTCACAAAACCTAGC CTTAGTGCTGTCTTAAAACACTTTAAAATTGTTGTTGATTGGTATTCTTCAAAAACCTTT AGTGATGAAGACTACTATCAATTCCAGCATATTTTGCTTGAGATTTACGGATTCATGCAT GATCATCTAAATGAAGGGAAAGATTCTTTTAGAGCCTTAAAATTTCCATGGGTTTGGACT GGCAAAAAGTTTTGTCCACTTGCCCAGGCTGTGATTAAACCAATCCATGATCTTGACCTT CAGCCTTATTTGCATAATGTACCTAAAACCATGGCAAAATTCCACCAACTATTTAAGGTC TGTGGTTCAATAGAGGAGTTGACATCAGATCATATTTCCATGGTTATTCAGAAGATATAT CTCAAAAGTGACCAAGATCTCAGTGAACAAGAAAGCAAACAAAATCTTCATCTTATGTTG AATATTATCAGATGGCTGTATAGCAATCAGATTCCAGCAAGCCCCAACACACCAGTTCCT ATACATCATAGCAAAAATCCTTCTAAACTTATCATGAAGCCAATTCACGAATGCTGTTAT TGTGACATTAAAGTTGATGACCTTAATGACTTACTTGAAGATTCTGTGGAACCAATCATT TTGGTGCATGAGGACATACCCATGAAAACTGCAGAATGGCTAAAAGTTCCATGCCTTAGT ACAAGACTGATAAATCCTGAAAACATGGGATTTGAGCAGTCAGGACAAAGAGAGCCACTT ACTGTAAGAATTAAAAATATTCTGGAAGAATACCCTTCAGTGTCAGATATTTTTAAAGAA CTACTTCAAAACGCTGATGATGCAAATGCAACAGAATGCAGTTTCTTGATTGATATGAGA AGAAATATGGACATAAGAGAGAATCTCCTAGACCCAGGGATGGCAGCTTGTCATGGACCT GCTTTGTGGTCATTCAACAATTCTCAATTCTCAGATTCAGATTTTGTGAACATAACTAGG TTAGGAGAATCTTTAAAAAGGGGAGAAGTTGACAAAGTTGGAAAATTTGGTCTTGGATTT AATTCTGTGTACCATATCACTGACATTCCCATCATTATGAGTCGGGAATTCATGATAATG TTCGATCCAAACATAAATCATATCAGTAAACACATTAAAGACAAATCCAATCCTGGGATC AAAATTAATTGGAGTAAACAACAGAAAAGACTTAGAAAATTTCCTAATCAGTTCAAACCA TTTATAGATGTATTTGGCTGTCAGTTACCTTTGACTGTAGAAGCACCTTACAGCTATAAT GGAACCCTTTTCCGACTGTCCTTTAGAACTCAACAGGAAGCAAAAGTGAGTGAAGTTAGT AGTACGTGCTACAATACAGCAGATATTTATTCTCTTGTGGATGAATTTAGTCTCTGTGGA CACAGGCTTATCATTTTCACTCAGAGTGTAAAGTCAATGTATTTGAAGTACTTGAAAATT GAGGAAACCAACCCCAGTTTAGCACAAGATACAGTAATAATTAAAAAAAAATCCTGCTCT TCCAAAGCATTGAACACACCTGTCTTAAGTGTTTTAAAAGAGGCTGCTAAGCTCATGAAG ACTTGCAGCAGCAGTAATAAAAAGCTTCCCAGTGATGAACCAAAGTCATCTTGCATTCTT CAGATCACAGTGGAAGAATTTCACCATGTGTTCAGAAGGATTGCTGATTTACAGTCGCCA CTTTTTAGAGGTCCAGATGATGACCCAGCTGCTCTCTTTGAAATGGCTAAGTCTGGCCAA TCAAAAAAGCCATCAGATGAGTTGTCACAGAAAACAGTAGAGTGTACCACGTGGCTTCTG TGTACTTGCATGGACACAGGAGAGGCTCTGAAGTTTTCCCTGAGTGAGAGTGGAAGAAGA CTAGGACTGGTTCCATGTGGGGCAGTAGGAGTTCAGCTGTCAGAAATCCAGGACCAGAAG TGGACAGTGAAACCACACATTGGAGAGGTGTTTTGCTATTTACCTTTACGAATAAAAACA GGCTTGCCAGTTCATATCAATGGGTGCTTTGCTGTTACATCAAATAGGAAAGAAATCTGG AAAACAGATACAAAAGGACGATGGAATACCACGTTCATGAGACATGTTATTGTGAAAGCT TACTTACAGGTACTGAGTGTCTTACGGGACCTGGCCACTAGTGGGGAGCTAATGGATTAT ACTTACTATGCAGTATGGCCCGATCCTGATTTAGTTCATGATGATTTTTCTGTAATTTGC CAAGGATTTTATGAAGATATAGCTCATGGAAAAGGGAAAGAACTGACCAAAGTCTTCTCT GATGGATCTACTTGGGTTTCCATGAAGAACGTAAGATTTCTAGATGACTCTATACTTAAA AGAAGAGATGTTGGTTCAGCAGCCTTCAAGATATTTTTGAAATACCTCAAGAAGACTGGG TCCAAAAACCTTTGTGCTGTTGAACTTCCTTCTTCGGTAAAATTAGGATTTGAAGAAGCT GGCTGCAAACAGATACTACTTGAAAACACATTTTCAGAGAAACAGTTTTTTTCTGAAGTG TTTTTTCCAAATATTCAAGAAATTGAAGCAGAACTTAGAGATCCTTTAATGATCTTTGTT CTAAATGAAAAAGTTGATGAGTTCTCGGGAGTTCTTCGTGTTACTCCATGTATTCCTTGT TCCTTGGAGGGGCATCCTTTGGTTTTGCCATCAAGATTGATCCACCCCGAAGGACGAGTT GCAAAGTTATTTGATATTAAAGATGGGAGATTCCCTTATGGTTCTACTCAGGATTATCTC AATCCTATTATTTTGATTAAACTAGTTCAGTTAGGTATGGCAAAAGATGATATTTTATGG GATGATATGCTAGAACGTGCAGTGTCAGTAGCTGAAATTAATAAAAGTGATCATGTTGCT GCATGCCTAAGAAGTAGTATCTTATTGAGTCTTATCGATGAGAAACTAAAAATAAGGGAT CCTAGAGCAAAGGATTTTGCTGCAAAATATCAAACAATCCGCTTCCTTCCATTTCTGACA AAACCAGCAGGTTTTTCTTTGGACTGGAAAGGCAACAGTTTTAAGCCTGAAACCATGTTT GCAGCAACTGACCTTTATACAGCTGAACATCAAGATATAGTTTGTCTTTTGCAACCAATT CTAAATGAAAATTCCCATTCTTTTAGAGGTTGTGGTTCAGTGTCATTGGCTGTTAAAGAG TTTTTGGGATTACTCAAGAAGCCAACAGTTGATCTGGTTATAAACCAATTGAAAGAAGTA GCAAAATCAGTTGATGATGGAATTACACTGTACCAGGAGAATATCACCAATGCTTGCTAC AAATACCTTCATGAAGCCTTGATGCAAAATGAAATCACTAAGATGTCAATTATTGATAAG TTAAAACCCTTTAGCTTCATTCTAGTTGAGAATGCATATGTTGACTCAGAAAAGGTTTCT TTTCATTTAAATTTTGAGGCGGCACCATACCTTTATCAGTTGCCTAATAAGTATAAAAAT AATTTCCGCGAACTTTTTGAAACCGTGGGTGTGAGGCAGTCATGCACTGTTGAAGATTTT GCTCTTGTTTTGGAATCTATTGATCAAGAAAGAGGAACAAAGCAAATAACAGAAGAGAAT TTTCAGCTTTGCCGACGAATAATCAGTGAAGGAATATGGAGTCTCATTAGAGAAAAGAAA CAAGAATTTTGTGAGAAAAATTATGGCAAGATATTATTGCCAGATACTAATCTTATGCTT CTCCCTGCTAAATCGTTATGCTACAATGATTGCCCTTGGATAAAAGTAAAGGATACCACT GTAAAATATTGTCATGCTGACATACCCAGGGAAGTAGCAGTAAAACTAGGAGCAGTCCCA AAGCGACACAAAGCCTTAGAAAGATATGCATCCAATGTCTGTTTTACAACACTTGGCACA GAATTTGGGCAGAAAGAAAAATTGACCAGCAGAATTAAGAGCATCCTTAATGCATATCCT TCTGAAAAGGAAATGTTGAAAGAGCTTCTTCAAAATGCTGATGATGCAAAGGCGACAGAA ATCTGTTTTGTGTTTGATCCTAGACAGCATCCAGTTGATAGAATATTTGATGATAAGTGG GCCCCATTGCAAGGGCCAGCACTTTGTGTGTACAACAACCAGCCATTTACAGAAGATGAT GTTAGAGGAATTCAGAATCTTGGAAAAGGCACGAAAGAGGGAAATCCTTATAAAACTGGA CAGTATGGAATAGGATTCAATTCTGTGTATCATATCACAGACTGCCCATCTTTTATTTCT GGCAATGACATCCTGTGTATTTTTGATCCTCATGCCAGATATGCACCAGGGGCCACATCC ATTAGTCCCGGACGCATGTTTAGAGATTTGGATGCAGATTTTAGGACACAGTTCTCAGAT GTTCTGGATCTTTATCTGGGAACCCATTTTAAACTGGATAATTGCACAATGTTCAGATTT CCTCTTCGTAATGCAGAAATGGCAAAAGTTTCGGAAATTTCGTCTGTTCCAGCATCAGAC AGAATGGTCCAGAATCTTTTGGACAAACTGCGCTCAGATGGGGCAGAACTTCTAATGTTT CTTAATCACATGGAAAAAATTTCTATTTGTGAAATAGATAAGAGTACTGGAGCTCTAAAT GTGCTGTATTCAGTAAAGGGCAAAATCACAGATGGAGACAGATTGAAAAGGAAACAATTT CATGCATCTGTAATTGATAGTGTTACTAAAAAGAGGCAGCTCAAAGACATACCAGTTCAA CAAATAACCTATACTATGGATACTGAGGACTCTGAAGGAAATCTTACTACGTGGCTAATT TGTAATAGATCAGGCTTTTCAAGTATGGAGAAAGTATCTAAAAGTGTCATATCAGCTCAC AAGAACCAAGATATTACTCTTTTCCCACGTGGTGGAGTAGCTGCCTGCATTACTCACAAC TATAAAAAACCCCATAGGGCCTTCTGTTTTTTGCCTCTTTCTTTGGAGACTGGGCTGCCA TTTCATGTGAATGGCCACTTTGCACTGGATTCAGCCAGAAGGAACCTGTGGCGTGATGAT AATGGAGTTGGTGTTCGAAGTGACTGGAATAACAGTTTAATGACAGCATTAATAGCTCCT GCATATGTTGAATTGCTAATACAGTTAAAAAAACGGTATTTCCCTGGTTCTGATCCAACA TTATCAGTGTTACAGAACACCCCTATTCATGTTGTAAAGGACACTTTAAAGAAGTTTTTA TCGTTTTTCCCAGTTAACCGTCTTGATCTACAGCCAGATTTATATTGTCTAGTGAAAGCA CTTTACAATTGCATTCACGAAGACATGAAACGTCTTTTACCTGTTGTGCGGGCTCCAAAT ATTGATGGCTCTGACTTGCACTCTGCAGTTATAATTACTTGGATCAATATGTCTACTTCT AATAAAACTAGACCATTTTTTGACAATTTACTACAGGATGAATTACAACACCTTAAAAAT GCAGATTATAATATCACCACACGCAAAACAGTAGCAGAGAATGTCTATAGGCTGAAACAT CTCCTTTTAGAAATTGGTTTCAACTTGGTTTATAACTGTGATGAAACTGCTAATCTTTAC CACTGTCTTATAGATGCAGATATTCCTGTTAGTTATGTGACCCCTGCTGATATCAGATCT TTTTTAATGACATTTTCCTCTCCTGACACTAATTGCCATATTGGGAAGCTGCCTTGTCGT CTGCAGCAGACTAATCTAAAACTTTTTCATAGTTTAAAACTTTTAGTTGATTATTGTTTT AAAGATGCAGAAGAAAATGAGATTGAAGTTGAGGGATTGCCCCTTCTCATCACACTGGAC AGTGTTTTGCAAACTTTTGATGCAAAACGACCCAAGTTTCTAACAACATATCATGAATTG ATTCCATCCCGCAAAGACTTGTTTATGAATACATTATATTTGAAATATAGTAATATTTTA TTGAACTGTAAAGTTGCAAAAGTGTTTGACATTTCCAGCTTTGCTGATTTGTTATCCTCT GTGTTGCCTCGAGAATATAAGACCAAAAGTTGCACAAAGTGGAAAGACAATTTTGCAAGT GAGTCTTGGCTTAAGAATGCATGGCATTTTATTAGTGAATCTGTAAGTGTGAAAGAAGAT CAGGAAGAAACAAAACCAACATTTGACATTGTTGTTGATACTCTAAAAGACTGGGCATTG CTTCCAGGAACAAAGTTTACTGTTTCAGCCAACCAGCTTGTGGTTCCTGAAGGAGATGTT CTGCTTCCTCTCAGCCTTATGCACATTGCAGTTTTTCCAAATGCCCAGAGTGATAAAGTT TTTCATGCTCTAATGAAAGCTGGCTGTATTCAGCTTGCTTTGAACAAAATCTGTTCCAAA GACAGTGCATTTGTTCCTTTGTTGTCATGTCACACAGCAAATATAGAGAGCCCCACAAGC ATCTTGAAGGCTCTACATTATATGGTCCAAACTTCAACATTTAGAGCAGAAAAATTAGTA GAAAATGATTTTGAGGCACTTTTGATGTATTTCAACTGCAATTTGAATCATTTGATGTCC CAAGATGATATAAAAATTCTAAAGTCACTTCCGTGCTATAAATCCATCAGTGGCCGCTAT GTAAGCATTGGAAAATTTGGAACATGCTACGTACTTACAAAAAGTATCCCTTCAGCTGAA GTGGAGAAATGGACACAGTCATCATCATCTGCATTTCTTGAAGAAAAAATACACTTAAAA GAACTATATGAGGTGATTGGTTGTGTACCTGTAGATGATCTTGAGGTATATTTGAAACAC CTCTTACCAAAAATTGAAAATCTCTCTTATGATGCAAAATTAGAGCACTTGATCTACCTT AAGAATAGATTATCAAGTGCTGAGGAATTATCAGAGATTAAGGAACAACTTTTTGAAAAA CTGGAAAGTTTATTGATAATCCATGATGCTAACAGTAGACTAAAGCAAGCAAAGCATTTC TATGATAGAACTGTGAGAGTTTTTGAAGTTATGCTTCCTGAAAAATTGTTTATTCCTAAT GATTTCTTTAAGAAATTGGAACAACTTATAAAACCCAAAAATCATGTTACATTTATGACA TCCTGGGTGGAATTCTTAAGAAATATTGGACTAAAATACATACTTTCTCAGCAGCAGTTG TTACAGTTTGCTAAGGAAATCAGTGTGAGGGCTAATACAGAAAACTGGTCCAAAGAAACA TTGCAAAATACAGTTGATATCCTTCTGCATCATATATTCCAAGAACGAATGGATTTGTTA TCTGGAAATTTTCTGAAAGAACTATCTTTAATACCATTCTTATGTCCTGAGCGGGCCCCC GCGGAATTCATTAGATTTCATCCTCAATATCAAGAGGTAAATGGAACACTTCCTCTTATA AAGTTCAATGGAGCACAGGTAAATCCAAAATTCAAGCAATGTGATGTACTCCAGCTGTTA TGGACATCCTGCCCTATTCTTCCAGAGAAAGCTACACCCTTAAGCATTAAAGAACAAGAA GGTAGTGACCTTGGTCCACAAGAACAGCTTGAACAAGTTTTAAATATGCTTAATGTTAAC CTGGATCCTCCTCTTGATAAGGTAATCAATAACTGCAGAAACATATGCAACATAACGACG TTGGATGAAGAAATGGTAAAAACTAGAGCAAAAGTCTTAAGGAGCATATATGAATTCCTC AGTGCAGAAAAAAGGGAATTTCGTTTTCAGTTGCGAGGGGTTGCTTTTGTGATGGTAGAA GATGGTTGGAAACTTCTGAAGCCTGAGGAGGTAGTCATAAACCTAGAATATGAATCTGAT TTTAAACCTTATTTGTACAAGCTACCTTTAGAACTTGGCACATTTCACCAGTTGTTCAAA CACTTAGGTACTGAAGATATTATTTCAACTAAGCAATATGTTGAAGTGTTGAGCCGCATA TTTAAAAATTCTGAGGGCAAACAATTAGATCCTAATGAAATGCGTACAGTTAAGAGAGTA GTTTCTGGTCTGTTCAGGAGTCTACAGAATGATTCAGTCAAGGTGAGGAGTGATCTCGAG AATGTACGAGACCTTGCGCTTTACCTCCCAAGCCAGGATGGTAGATTGGTAAAGTCAAGC ATCTTAGTGTTTGACGATGCGCCACATTATAAAAGTAGAATCCAGGGGAATATTGGTGTG CAAATGTTAGTTGATCTCAGCCAGTGCTACTTAGGGAAAGACCATGGATTTCACACTAAG TTGATAATGCTCTTTCCTCAAAAACTTAGACCTCGATTATTGAGCAGTATACTTGAAGAA CAATTAGATGAAGAGACTCCCAAAGTTTGTCAGTTTGGAGCGTTGTGTTCTCTTCAAGGA AGATTGCAGTTACTCTTGTCTTCTGAACAGTTCATTACAGGACTGATTAGAATTATGAAG CATGAAAATGATAATGCTTTTCTGGCCAATGAAGAAAAAGCCATAAGACTTTGCAAAGCC CTAAGAGAAGGATTGAAAGTATCCTGCTTTGAAAAGCTTCAAACAACATTAAGAGTTAAA GGTTTTAATCCTATTCCCCACAGCAGAAGTGAAACTTTTGCTTTTTTGAAGCGATTTGGT AATGCAGTCATCTTGCTCTACATTCAACATTCAGACAGTAAAGACATTAATTTCCTGTTA GCATTGGCAATGACTCTTAAATCAGCAACTGACAATTTGATTTCTGACACTTCATATTTA ATTGCTATGCTAGGATGCAATGATATTTACAGGATTGGTGAGAAACTTGACAGTTTAGGA GTGAAATATGACTCTTCGGAGCCATCAAAACTGGAACTTCCAATGCCTGGCACACCAATT CCTGCTGAAATTCATTACACTCTGCTTATGGACCCAATGAATGTTTTTTACCCGGGAGAA TATGTTGGGTACCTTGTTGATGCTGAAGGTGGTGATATCTATGGATCATACCAGCCAACA TACACATATGCAATTATTGTACAAGAAGTTGAAAGAGAAGATGCTGACAATTCTAGTTTT CTAGGAAAGATATATCAGATAGATATTGGTTATAGTGAATATAAAATAGTTAGCTCTCTT GATCTGTATAAGTTTTCAAGACCTGAGGAAAGCTCTCAAAGCAGGGACAGTGCTCCTTCT ACACCAACCAGCCCCACTGAGTTCCTCACCCCTGGCCTGAGAAGCATTCCTCCTCTTTTC TCTGGTAGAGAGAGCCACAAGACTTCTTCCAAACATCAGTCCCCCAAAAAGCTTAAGGTT AATTCTTTACCAGAAATCTTAAAAGAAGTGACATCTGTGGTGGAGCAAGCATGGAAGCTT CCAGAATCGGAACGAAAAAAGATTATTAGGCGGTTGTATTTGAAATGGCATCCTGACAAA AATCCAGAGAACCATGACATTGCCAATGAAGTTTTTAAACATTTGCAGAATGAAATCAAC AGATTAGAAAAACAGGCTTTTCTAGATCAAAATGCAGACAGGGCCTCCAGACGAACATTT TCAACCTCAGCATCCCGATTTCAGTCAGACAAATACTCATTTCAGAGATTCTATACTTCA TGGAATCAAGAAGCAACGAGCCATAAATCTGAAAGACAGCAACAGAACAAAGAAAAATGC CCCCCTTCAGCCGGACAGACTTACTCTCAAAGGTTCTTTGTTCCTCCCACTTTCAAGTCG GTTGGCAATCCAGTGGAAGCACGCAGATGGCTAAGACAAGCCAGAGCAAACTTCTCAGCT GCCAGGAATGACCTTCATAAAAATGCCAATGAGTGGGTGTGCTTTAAATGTTACCTTTCT ACCAAGTTAGCTTTGATTGCAGCTGACTATGCTGTGAGGGGAAAGTCTGATAAAGATGTA AAACCAACTGCACTTGCTCAGAAAATAGAGGAATATAGTCAGCAACTTGAAGGACTGACA AATGATGTTCACACATTGGAAGCTTATGGTGTAGACAGTTTAAAAACAAGATACCCTGAT TTGCTTCCCTTTCCTCAGATCCCAAATGACAGGTTCACTTCTGAGGTTGCTATGAGGGTG ATGGAATGTACTGCCTGTATCATAATAAAACTTGAAAATTTTATGCAACAAAAAGTG |
| Restriction Sites | Please inquire |
| ACCN | NM_014363 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014363.4, NP_055178.3 |
| RefSeq Size | 15639 bp |
| RefSeq ORF | 13740 bp |
| Locus ID | 26278 |
| UniProt ID | Q9NZJ4 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes the sacsin protein, which includes a UbL domain at the N-terminus, a DnaJ domain, and a HEPN domain at the C-terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12.8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disorder characterized by early-onset cerebellar ataxia with spasticity and peripheral neuropathy. The authors of a publication on the effects of siRNA-mediated sacsin knockdown concluded that sacsin protects against mutant ataxin-1 and suggest that "the large multi-domain sacsin protein is able to recruit Hsp70 chaperone action and has the potential to regulate the effects of other ataxia proteins" (Parfitt et al., PubMed: 19208651). A pseudogene associated with this gene is located on chromosome 11. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignment of partial transcripts and data in published reports. |
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