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Sacsin (SACS) (NM_014363) Human Untagged Clone
CAT＃: SC304089
SACS (untagged)-Human spastic ataxia of Charlevoix-Saguenay (sacsin) (SACS)
CNY 42,296.00
货期*
现货
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARSACS; DNAJC29; PPP1R138; SPAX6 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_014363 edited
ACGCCACCACTTGTTGATTTTCTCAAGGACATTTTGAGAAGATATCCAGAAGGAGGACAG ATTCTTAAGGAATTAATTCAGAATGCAGAAGATGCTGGGGCGACAGAAGTTAAATTTTTA TATGATGAAACTCAATACGGAACAGAGACTCTTTGGTCAAAAGATATGGCGCCATATCAG GGGCCAGCTCTCTATGTGTACAACAACGCGGTTTTCACCCCAGAGGACTGGCACGGCATT CAAGAAATAGCAAGAAGCAGGAAAAAGGATGATCCTCTGAAGGTCGGAAGATTTGGAATT GGGTTTAATTCTGTCTATCATATAACAGATGTTCCTTGTATCTTTAGTGGTGACCAAATC GGGATGCTAGATCCTCATCAAACACTTTTTGGCCCACATGAATCAGGCCAATGTTGGAAA CTCAAAGATGACAGCAAAGAAATTAGTGAACTTTCAGACCAGTTTGCACCATTTGTTGGC ATTTTTGGAAGCACCAAGGAAACATTTATAAACGGCAATTTTCCAGGAACATTTTTCCGT TTCCCTCTTCGCCTACAACCTTCACAACTTAGTAGTAACCTCTACAATAAGCAGAAGGTT CTTGAGTTGTTTGAGTCTTTTAGGGCAGATGCAGACACAGTGCTGCTCTTTCTGAAAAGT GTGCAGGATGTTTCCTTATATGTCCGAGAGGCTGACGGAACAGAGAAACTGGTGTTTAGA GTGACTTCGAGTGAGAGTAAGGCACTGAAACATGAGCGGCCGAATTCTATAAAGATTCTG GGAACTGCTATAAGTAACTATTGTAAAAAGACTCCAAGCAATAACATCACCTGTGTAACA TATCACGTAAATATTGTTTTAGAAGAGGAGAGTACTAAGGATGCACAGAAAACATCTTGG TTGGTGTGTAACAGTGTGGGTGGGCGAGGGATCAGTAGTAAGCTTGACTCTTTAGCTGAT GAACTGAAATTTGTCCCAATCATTGGAATAGCCATGCCTTTATCAAGCAGAGATGATGAA GCAAAAGGAGCAACGTCTGATTTCTCAGGAAAAGCATTTTGTTTCCTTCCTTTACCACCT GGTGAGGAAAGCAGCACAGGCCTCCCAGTTCACATCAGTGGGTTCTTTGGCCTTACTGAT AACCGCAGGAGCATAAAATGGAGAGAGCTGGACCAGTGGAGAGACCCGGCAGCCTTATGG AATGAGTTTCTTGTCATGAATGTTGTCCCCAAAGCTTATGCTACTCTGATCTTAGATTCA ATAAAACGTCTGGAGATGGAAAAGAGCTCTGATTTCCCCTTGTCAGTTGATGTTATCTAT AAGCTTTGGCCGGAGGCGAGCAAAGTCAAGGTGCACTGGCAACCGGTGTTAGAGCCTCTG TTCAGCGAGCTGTTGCAGAATGCAGTGATTTATTCAATTAGCTGTGACTGGGTCAGGTTG GAGCAGGTGTACTTCTCAGAACTTGATGAAAATTTAGAATACACAAAAACTGTGCTCAAC TACCTCCAGAGCTCAGGGAAGCAGATTGCCAAGGTACCAGGGAATGTGGATGCTGCTGTT CAGCTCACAGCTGCCTCTGGCACAACACCTGTGAGGAAGGTGACGCCCGCGTGGGTGCGG CAGGTGCTGCGGAAGTGTGCACACCTGGGCTGTGCTGAAGAAAAGCTTCACCTTCTAGAA TTTGTGCTTTCTGACCAAGCCTACAGTGAGCTGCTTGGGCTGGAGCTGCTCCCTTTACAA AATGGCAATTTTGTCCCCTTCTCCTCATCTGTATCAGACCAAGATGTCATTTATATTACC TCAGCAGAATATCCAAGGTCCCTTTTCCCAAGTCTTGAAGGAAGATTTATTTTGGATAAC TTGAAACCTCACCTTGTGGCTGCTTTAAAGGAAGCTGCCCAAACCCGAGGAAGACCATGT ACTCAGCTGCAGCTTCTAAATCCAGAACGATTTGCACGTCTTATCAAGGAAGTAATGAAT ACATTCTGGCCTGGCAGAGAATTGATTGTTCAATGGTATCCATTTGATGAAAACAGAAAT CACCCATCTGTTTCATGGCTTAAGATGGTTTGGAAAAATCTTTATATACATTTTTCAGAG GATTTGACTTTATTTGATGAGATGCCACTTATCCCCAGAACTATACTAGAGGAAGGTCAG ACATGTGTGGAACTCATTAGACTCAGGATTCCATCGTTAGTCATTTTAGACGATGAATCT GAAGCACAGCTTCCAGAATTTTTAGCAGACATTGTACAAAAACTTGGAGGGTTTGTCCTT AAAAAATTAGATGCATCTATACAACATCCGCTTATTAAAAAATATATTCATTCACCATTA CCAAGTGCTGTTTTGCAGATAATGGAGAAGATGCCATTGCAGAAATTGTGTAATCAAATA ACTTCGCTACTTCCAACACACAAAGATGCCCTGAGGAAGTTCTTGGCTAGTTTAACCGAT AGCAGTGAGAAAGAGAAAAGAATTATTCAAGAATTGGCAATATTCAAGCGCATTAACCAT TCTTCTGATCAGGGAATTTCCTCTTATACAAAATTGAAAGGTTGTAAAGTCTTACACCAT ACTGCCAAACTCCCAGCAGATCTGCGACTTTCTATTTCAGTAATAGACAGTAGTGATGAA GCTACTATTCGTCTGGCAAACATGTTGAAAATAGAACAGTTAAAGACCACTAGCTGCTTA AAGCTTGTTTTAAAAGATATTGAAAATGCATTTTATTCACATGAAGAGGTAACACAGCTT ATGTTATGGGTCCTTGAGAATCTATCTTCTCTTAAAAATGAGAATCCAAATGTGCTTGAG TGGTTAACACCATTAAAATTCATCCAGATATCACAGGAACAGATGGTATCAGCTGGTGAA CTCTTTGACCCTGATATAGAAGTACTAAAGGATCTCTTTTGTAATGAAGAAGGAACCTAT TTCCCACCCTCAGTTTTTACCTCACCAGATATTCTTCACTCCTTAAGACAGATTGGTTTA AAAAACGAAGCCAGTCTCAAAGAAAAGGATGTTGTGCAAGTGGCAAAAAAAATTGAAGCC TTACAGGTCGGTGCTTGTCCTGATCAAGATGTTCTTCTGAAGAAAGCCAAAACCCTCTTA CTGGTTTTAAATAAGAATCACACACTGTTGCAATCATCTGAAGGAAAGATGACATTGAAG AAAATAAAATGGGTTCCAGCCTGCAAGGAAAGGCCTCCAAATTATCCAGGCTCTTTGGTC TGGAAAGGAGATCTCTGTAATCTCTGTGCACCACCAGATATGTGTGATGTAGGCCATGCA ATTCTCATTGGCTCCTCACTTCCTCTTGTTGAAAGTATCCATGTAAACCTGGAAAAAGCA TTAGGGATCTTCACAAAACCTAGCCTTAGTGCTGTCTTAAAACACTTTAAAATTGTTGTT GATTGGTATTCTTCAAAAACCTTTAGTGATGAAGACTACTATCAATTCCAGCATATTTTG CTTGAGATTTACGGATTCATGCATGATCATCTAAATGAAGGGAAAGATTCTTTTAGAGCC TTAAAATTTCCATGGGTTTGGACTGGCAAAAAGTTTTGTCCACTTGCCCAGGCTGTGATT AAACCAATCCATGATCTTGACCTTCAGCCTTATTTGCATAATGTACCTAAAACCATGGCA AAATTCCACCAACTATTTAAGGTCTGTGGTTCAATAGAGGAGTTGACATCAGATCATATT TCCATGGTTATTCAGAAGATATATCTCAAAAGTGACCAAGATCTCAGTGAACAAGAAAGC AAACAAAATCTTCATCTTATGTTGAATATTATCAGATGGCTGTATAGCAATCAGATTCCA GCAAGCCCCAACACACCAGTTCCTATACATCATAGCAAAAATCCTTCTAAACTTATCATG AAGCCAATTCACGAATGCTGTTATTGTGACATTAAAGTTGATGACCTTAATGACTTACTT GAAGATTCTGTGGAACCAATCATTTTGGTGCATGAGGACATACCCATGAAAACTGCAGAA TGGCTAAAAGTTCCATGCCTTAGTACAAGACTGATAAATCCTGAAAACATGGGATTTGAG CAGTCAGGACAAAGAGAGCCACTTACTGTAAGAATTAAAAATATTCTGGAAGAATACCCT TCAGTGTCAGATATTTTTAAAGAACTACTTCAAAACGCTGATGATGCAAATGCAACAGAA TGCAGTTTCTTGATTGATATGAGAAGAAATATGGACATAAGAGAGAATCTCCTAGACCCA GGGATGGCAGCTTGTCATGGACCTGCTTTGTGGTCATTCAACAATTCTCAATTCTCAGAT TCAGATTTTGTGAACATAACTAGGTTAGGAGAATCTTTAAAAAGGGGAGAAGTTGACAAA GTTGGAAAATTTGGTCTTGGATTTAATTCTGTGTACCATATCACTGACATTCCCATCATT ATGAGTCGGGAATTCATGATAATGTTCGATCCAAACATAAATCATATCAGTAAACACATT AAAGACAAATCCAATCCTGGGATCAAAATTAATTGGAGTAAACAACAGAAAAGACTTAGA AAATTTCCTAATCAGTTCAAACCATTTATAGATGTATTTGGCTGTCAGTTACCTTTGACT GTAGAAGCACCTTACAGCTATAATGGAACCCTTTTCCGACTGTCCTTTAGAACTCAACAG GAAGCAAAAGTGAGTGAAGTTAGTAGTACGTGCTACAATACAGCAGATATTTATTCTCTT GTGGATGAATTTAGTCTCTGTGGACACAGGCTTATCATTTTCACTCAGAGTGTAAAGTCA ATGTATTTGAAGTACTTGAAAATTGAGGAAACCAACCCCAGTTTAGCACAAGATACAGTA ATAATTAAAAAAAAATCCTGCTCTTCCAAAGCATTGAACACACCTGTCTTAAGTGTTTTA AAAGAGGCTGCTAAGCTCATGAAGACTTGCAGCAGCAGTAATAAAAAGCTTCCCAGTGAT GAACCAAAGTCATCTTGCATTCTTCAGATCACAGTGGAAGAATTTCACCATGTGTTCAGA AGGATTGCTGATTTACAGTCGCCACTTTTTAGAGGTCCAGATGATGACCCAGCTGCTCTC TTTGAAATGGCTAAGTCTGGCCAATCAAAAAAGCCATCAGATGAGTTGTCACAGAAAACA GTAGAGTGTACCACGTGGCTTCTGTGTACTTGCATGGACACAGGAGAGGCTCTGAAGTTT TCCCTGAGTGAGAGTGGAAGAAGACTAGGACTGGTTCCATGTGGGGCAGTAGGAGTTCAG CTGTCAGAAATCCAGGACCAGAAGTGGACAGTGAAACCACACATTGGAGAGGTGTTTTGC TATTTACCTTTACGAATAAAAACAGGCTTGCCAGTTCATATCAATGGGTGCTTTGCTGTT ACATCAAATAGGAAAGAAATCTGGAAAACAGATACAAAAGGACGATGGAATACCACGTTC ATGAGACATGTTATTGTGAAAGCTTACTTACAGGTACTGAGTGTCTTACGGGACCTGGCC ACTAGTGGGGAGCTAATGGATTATACTTACTATGCAGTATGGCCCGATCCTGATTTAGTT CATGATGATTTTTCTGTAATTTGCCAAGGATTTTATGAAGATATAGCTCATGGAAAAGGG AAAGAACTGACCAAAGTCTTCTCTGATGGATCTACTTGGGTTTCCATGAAGAACGTAAGA TTTCTAGATGACTCTATACTTAAAAGAAGAGATGTTGGTTCAGCAGCCTTCAAGATATTT TTGAAATACCTCAAGAAGACTGGGTCCAAAAACCTTTGTGCTGTTGAACTTCCTTCTTCG GTAAAATTAGGATTTGAAGAAGCTGGCTGCAAACAGATACTACTTGAAAACACATTTTCA GAGAAACAGTTTTTTTCTGAAGTGTTTTTTCCAAATATTCAAGAAATTGAAGCAGAACTT AGAGATCCTTTAATGATCTTTGTTCTAAATGAAAAAGTTGATGAGTTCTCGGGAGTTCTT CGTGTTACTCCATGTATTCCTTGTTCCTTGGAGGGGCATCCTTTGGTTTTGCCATCAAGA TTGATCCACCCCGAAGGACGAGTTGCAAAGTTATTTGATATTAAAGATGGGAGATTCCCT TATGGTTCTACTCAGGATTATCTCAATCCTATTATTTTGATTAAACTAGTTCAGTTAGGT ATGGCAAAAGATGATATTTTATGGGATGATATGCTAGAACGTGCAGTGTCAGTAGCTGAA ATTAATAAAAGTGATCATGTTGCTGCATGCCTAAGAAGTAGTATCTTATTGAGTCTTATC GATGAGAAACTAAAAATAAGGGATCCTAGAGCAAAGGATTTTGCTGCAAAATATCAAACA ATCCGCTTCCTTCCATTTCTGACAAAACCAGCAGGTTTTTCTTTGGACTGGAAAGGCAAC AGTTTTAAGCCTGAAACCATGTTTGCAGCAACTGACCTTTATACAGCTGAACATCAAGAT ATAGTTTGTCTTTTGCAACCAATTCTAAATGAAAATTCCCATTCTTTTAGAGGTTGTGGT TCAGTGTCATTGGCTGTTAAAGAGTTTTTGGGATTACTCAAGAAGCCAACAGTTGATCTG GTTATAAACCAATTGAAAGAAGTAGCAAAATCAGTTGATGATGGAATTACACTGTACCAG GAGAATATCACCAATGCTTGCTACAAATACCTTCATGAAGCCTTGATGCAAAATGAAATC ACTAAGATGTCAATTATTGATAAGTTAAAACCCTTTAGCTTCATTCTAGTTGAGAATGCA TATGTTGACTCAGAAAAGGTTTCTTTTCATTTAAATTTTGAGGCGGCACCATACCTTTAT CAGTTGCCTAATAAGTATAAAAATAATTTCCGCGAACTTTTTGAAACCGTGGGTGTGAGG CAGTCATGCACTGTTGAAGATTTTGCTCTTGTTTTGGAATCTATTGATCAAGAAAGAGGA ACAAAGCAAATAACAGAAGAGAATTTTCAGCTTTGCCGACGAATAATCAGTGAAGGAATA TGGAGTCTCATTAGAGAAAAGAAACAAGAATTTTGTGAGAAAAATTATGGCAAGATATTA TTGCCAGATACTAATCTTATGCTTCTCCCTGCTAAATCGTTATGCTACAATGATTGCCCT TGGATAAAAGTAAAGGATACCACTGTAAAATATTGTCATGCTGACATACCCAGGGAAGTA GCAGTAAAACTAGGAGCAGTCCCAAAGCGACACAAAGCCTTAGAAAGATATGCATCCAAT GTCTGTTTTACAACACTTGGCACAGAATTTGGGCAGAAAGAAAAATTGACCAGCAGAATT AAGAGCATCCTTAATGCATATCCTTCTGAAAAGGAAATGTTGAAAGAGCTTCTTCAAAAT GCTGATGATGCAAAGGCGACAGAAATCTGTTTTGTGTTTGATCCTAGACAGCATCCAGTT GATAGAATATTTGATGATAAGTGGGCCCCATTGCAAGGGCCAGCACTTTGTGTGTACAAC AACCAGCCATTTACAGAAGATGATGTTAGAGGAATTCAGAATCTTGGAAAAGGCACGAAA GAGGGAAATCCTTATAAAACTGGACAGTATGGAATAGGATTCAATTCTGTGTATCATATC ACAGACTGCCCATCTTTTATTTCTGGCAATGACATCCTGTGTATTTTTGATCCTCATGCC AGATATGCACCAGGGGCCACATCCATTAGTCCCGGACGCATGTTTAGAGATTTGGATGCA GATTTTAGGACACAGTTCTCAGATGTTCTGGATCTTTATCTGGGAACCCATTTTAAACTG GATAATTGCACAATGTTCAGATTTCCTCTTCGTAATGCAGAAATGGCAAAAGTTTCGGAA ATTTCGTCTGTTCCAGCATCAGACAGAATGGTCCAGAATCTTTTGGACAAACTGCGCTCA GATGGGGCAGAACTTCTAATGTTTCTTAATCACATGGAAAAAATTTCTATTTGTGAAATA GATAAGAGTACTGGAGCTCTAAATGTGCTGTATTCAGTAAAGGGCAAAATCACAGATGGA GACAGATTGAAAAGGAAACAATTTCATGCATCTGTAATTGATAGTGTTACTAAAAAGAGG CAGCTCAAAGACATACCAGTTCAACAAATAACCTATACTATGGATACTGAGGACTCTGAA GGAAATCTTACTACGTGGCTAATTTGTAATAGATCAGGCTTTTCAAGTATGGAGAAAGTA TCTAAAAGTGTCATATCAGCTCACAAGAACCAAGATATTACTCTTTTCCCACGTGGTGGA GTAGCTGCCTGCATTACTCACAACTATAAAAAACCCCATAGGGCCTTCTGTTTTTTGCCT CTTTCTTTGGAGACTGGGCTGCCATTTCATGTGAATGGCCACTTTGCACTGGATTCAGCC AGAAGGAACCTGTGGCGTGATGATAATGGAGTTGGTGTTCGAAGTGACTGGAATAACAGT TTAATGACAGCATTAATAGCTCCTGCATATGTTGAATTGCTAATACAGTTAAAAAAACGG TATTTCCCTGGTTCTGATCCAACATTATCAGTGTTACAGAACACCCCTATTCATGTTGTA AAGGACACTTTAAAGAAGTTTTTATCGTTTTTCCCAGTTAACCGTCTTGATCTACAGCCA GATTTATATTGTCTAGTGAAAGCACTTTACAATTGCATTCACGAAGACATGAAACGTCTT TTACCTGTTGTGCGGGCTCCAAATATTGATGGCTCTGACTTGCACTCTGCAGTTATAATT ACTTGGATCAATATGTCTACTTCTAATAAAACTAGACCATTTTTTGACAATTTACTACAG GATGAATTACAACACCTTAAAAATGCAGATTATAATATCACCACACGCAAAACAGTAGCA GAGAATGTCTATAGGCTGAAACATCTCCTTTTAGAAATTGGTTTCAACTTGGTTTATAAC TGTGATGAAACTGCTAATCTTTACCACTGTCTTATAGATGCAGATATTCCTGTTAGTTAT GTGACCCCTGCTGATATCAGATCTTTTTTAATGACATTTTCCTCTCCTGACACTAATTGC CATATTGGGAAGCTGCCTTGTCGTCTGCAGCAGACTAATCTAAAACTTTTTCATAGTTTA AAACTTTTAGTTGATTATTGTTTTAAAGATGCAGAAGAAAATGAGATTGAAGTTGAGGGA TTGCCCCTTCTCATCACACTGGACAGTGTTTTGCAAACTTTTGATGCAAAACGACCCAAG TTTCTAACAACATATCATGAATTGATTCCATCCCGCAAAGACTTGTTTATGAATACATTA TATTTGAAATATAGTAATATTTTATTGAACTGTAAAGTTGCAAAAGTGTTTGACATTTCC AGCTTTGCTGATTTGTTATCCTCTGTGTTGCCTCGAGAATATAAGACCAAAAGTTGCACA AAGTGGAAAGACAATTTTGCAAGTGAGTCTTGGCTTAAGAATGCATGGCATTTTATTAGT GAATCTGTAAGTGTGAAAGAAGATCAGGAAGAAACAAAACCAACATTTGACATTGTTGTT GATACTCTAAAAGACTGGGCATTGCTTCCAGGAACAAAGTTTACTGTTTCAGCCAACCAG CTTGTGGTTCCTGAAGGAGATGTTCTGCTTCCTCTCAGCCTTATGCACATTGCAGTTTTT CCAAATGCCCAGAGTGATAAAGTTTTTCATGCTCTAATGAAAGCTGGCTGTATTCAGCTT GCTTTGAACAAAATCTGTTCCAAAGACAGTGCATTTGTTCCTTTGTTGTCATGTCACACA GCAAATATAGAGAGCCCCACAAGCATCTTGAAGGCTCTACATTATATGGTCCAAACTTCA ACATTTAGAGCAGAAAAATTAGTAGAAAATGATTTTGAGGCACTTTTGATGTATTTCAAC TGCAATTTGAATCATTTGATGTCCCAAGATGATATAAAAATTCTAAAGTCACTTCCGTGC TATAAATCCATCAGTGGCCGCTATGTAAGCATTGGAAAATTTGGAACATGCTACGTACTT ACAAAAAGTATCCCTTCAGCTGAAGTGGAGAAATGGACACAATCATCATCATCTGCATTT CTTGAAGAAAAAATACACTTAAAAGAACTATATGAGGTGATTGGTTGTGTACCTGTAGAT GATCTTGAGGTATATTTGAAACACCTCTTACCAAAAATTGAAAATCTCTCTTATGATGCA AAATTAGAGCACTTGATCTACCTTAAGAATAGATTATCAAGTGCTGAGGAATTATCAGAG ATTAAGGAACAACTTTTTGAAAAACTGGAAAGTTTATTGATAATCCATGATGCTAACAGT AGACTAAAGCAAGCAAAGCATTTCTATGATAGAACTGTGAGAGTTTTTGAAGTTATGCTT CCTGAAAAATTGTTTATTCCTAATGATTTCTTTAAGAAATTGGAACAACTTATAAAACCC AAAAATCATGTTACATTTATGACATCCTGGGTGGAATTCTTAAGAAATATTGGACTAAAA TACATACTTTCTCAGCAGCAGTTGTTACAGTTTGCTAAGGAAATCAGTGTGAGGGCTAAT ACAGAAAACTGGTCCAAAGAAACATTGCAAAATACAGTTGATATCCTTCTGCATCATATA TTCCAAGAACGAATGGATTTGTTATCTGGAAATTTTCTGAAAGAACTATCTTTAATACCA TTCTTATGTCCTGAGCGGGCCCCCGCGGAATTCATTAGATTTCATCCTCAATATCAAGAG GTAAATGGAACACTTCCTCTTATAAAGTTCAATGGAGCACAGGTAAATCCAAAATTCAAG CAATGTGATGTACTCCAGCTGTTATGGACATCCTGCCCTATTCTTCCAGAGAAAGCTACA CCCTTAAGCATTAAAGAACAAGAAGGTAGTGACCTTGGTCCACAAGAACAGCTTGAACAA GTTTTAAATATGCTTAATGTTAACCTGGATCCTCCTCTTGATAAGGTAATCAATAACTGC AGAAACATATGCAACATAACGACGTTGGATGAAGAAATGGTAAAAACTAGAGCAAAAGTC TTAAGGAGCATATATGAATTCCTCAGTGCAGAAAAAAGGGAATTTCGTTTTCAGTTGCGA GGGGTTGCTTTTGTGATGGTAGAAGATGGTTGGAAACTTCTGAAGCCTGAGGAGGTAGTC ATAAACCTAGAATATGAATCTGATTTTAAACCTTATTTGTACAAGCTACCTTTAGAACTT GGCACATTTCACCAGTTGTTCAAACACTTAGGTACTGAAGATATTATTTCAACTAAGCAA TATGTTGAAGTGTTGAGCCGCATATTTAAAAATTCTGAGGGCAAACAATTAGATCCTAAT GAAATGCGTACAGTTAAGAGAGTAGTTTCTGGTCTGTTCAGGAGTCTACAGAATGATTCA GTCAAGGTGAGGAGTGATCTCGAGAATGTACGAGACCTTGCGCTTTACCTCCCAAGCCAG GATGGTAGATTGGTAAAGTCAAGCATCTTAGTGTTTGACGATGCGCCACATTATAAAAGT AGAATCCAGGGGAATATTGGTGTGCAAATGTTAGTTGATCTCAGCCAGTGCTACTTAGGG AAAGACCATGGATTTCACACTAAGTTGATAATGCTCTTTCCTCAAAAACTTAGACCTCGA TTATTGAGCAGTATACTTGAAGAACAATTAGATGAAGAGACTCCCAAAGTTTGTCAGTTT GGAGCGTTGTGTTCTCTTCAAGGAAGATTGCAGTTACTCTTGTCTTCTGAACAGTTCATT ACAGGACTGATTAGAATTATGAAGCATGAAAATGATAATGCTTTTCTGGCCAATGAAGAA AAAGCCATAAGACTTTGCAAAGCCCTAAGAGAAGGATTGAAAGTATCCTGCTTTGAAAAG CTTCAAACAACATTAAGAGTTAAAGGTTTTAATCCTATTCCCCACAGCAGAAGTGAAACT TTTGCTTTTTTGAAGCGATTTGGTAATGCAGTCATCTTGCTCTACATTCAACATTCAGAC AGTAAAGACATTAATTTCCTGTTAGCACTGGCAATGACTCTTAAATCAGCAACTGACAAT TTGATTTCTGACACTTCATATTTAATTGCTATGCTAGGATGCAATGATATTTACAGGATT GGTGAGAAACTTGACAGTTTAGGAGTGAAATATGACTCTTCGGAGCCATCAAAACTGGAA CTTCCAATGCCTGGCACACCAATTCCTGCTGAAATTCATTACACTCTGCTTATGGACCCA ATGAATGTTTTTTACCCGGGAGAATATGTTGGGTACCTTGTTGATGCTGAAGGTGGTGAT ATCTATGGATCATACCAGCCAACATACACATATGCAATTATTGTACAAGAAGTTGAAAGA GAAGATGCTGACAATTCTAGTTTTCTAGGAAAGATATATCAGATAGATATTGGTTATAGT GAATATAAAATAGTTAGCTCTCTTGATCTGTATAAGTTTTCAAGACCTGAGGAAAGCTCT CAAAGCAGGGACAGTGCTCCTTCTACACCAACCAGCCCCACTGAGTTCCTCACCCCTGGC CTGAGAAGCATTCCTCCTCTTTTCTCTGGTAGAGAGAGCCACAAGACTTCTTCCAAACAT CAGTCCCCCAAAAAGCTTAAGGTTAATTCTTTACCAGAAATCTTAAAAGAAGTGACATCT GTGGTGGAGCAAGCATGGAAGCTTCCAGAATCGGAACGAAAAAAGATTATTAGGCGGTTG TATTTGAAATGGCATCCTGACAAAAATCCAGAGAACCATGACATTGCCAATGAAGTTTTT AAACATTTGCAGAATGAAATCAACAGATTAGAAAAACAGGCTTTTCTAGATCAAAATGCA GACAGGGCCTCCAGACGAACATTTTCAACCTCAGCATCCCGATTTCAGTCAGACAAATAC TCATTTCAGAGATTCTATACTTCATGGAATCAAGAAGCAACGAGCCATAAATCTGAAAGA CAGCAACAGAACAAAGAAAAATGCCCCCCTTCAGCCGGACAGACTTACTCTCAAAGGTTC TTTGTTCCTCCCACTTTCAAGTCGGTTGGCAATCCAGTGGAAGCACGCAGATGGCTAAGA CAAGCCAGAGCAAACTTCTCAGCTGCCAGGAATGACCTTCATAAAAATGCCAATGAGTGG GTGTGCTTTAAATGTTACCTTTCTACCAAGTTAGCTTTGATTGCAGCTGACTATGCTGTG AGGGGAAAGTCTGATAAAGATGTAAAACCAACTGCACTTGCTCAGAAAATAGAGGAATAT AGTCAGCAACTTGAAGGACTGACAAATGATGTTCACACATTGGAAGCTTATGGTGTAGAC AGTTTAAAAACAAGATACCCTGATTTGCTTCCCTTTCCTCAGATCCCAAATGACAGGTTC ACTTCTGAGGTTGCTATGAGGGTGATGGAATGTACTGCCTGTATCATAATAAAACTTGAA AATTTTATGCAACAAAAAGTGTGAAGATATTTAACGAAAAAAAAGGTAGATCTTGAATGT GTTGTAGCACGAATAAATTGCTGTACTTCATTAAGCTTCATTGCCAATTAGCTAGGAATT GTTAAGCACATTGCAGATTGTTCTTGGAGAATTCTGGAGTTGTTATGAACATGAATACCA ACGGAAAACCTTAACTGAATCTAAAAGAAAACTATTTTGAAGATGGTGGTGAGCTGCAAA ATAGCTGGATGGATTTGAATGATTGGGATGATACATCATTGAACTGCACTTTATATAACC AAAGCTTAGCAGTTTGTTAGATAAGAGTCTATGTATGTCTCTGGTTAGGATGAAGTTAAT TTTATGTTTTTAACATGGTATTTTTGAAGGAGCTAATGAAACACTGGACATATAATTGGT TTAAACATAAGGGGAATTAAGTCTTTGTAGTCTGTCATTTTTTTAAGTGGATCCTCTTGG ATGCGTTATTTTCTCATCAGCTGGCTCTGATCATGAATTTGTTGTAATTTTATGTTGTAC TCAGTGCATTTAAGAAATGGTAGAGTATTTTAATCCTATTACTTGACTAAGAGTGTGAAG GTAGTACTTTTTAGAGTGCACTGAGTGCACTTTACATCTTTATTTAAATTTTTTTTTAAC ATCTTATGTTTACAGGCTTCCTGTTTGATGAAGATAGCAACGGAAAACTCAAAATGGTGG CAGTTCTTATTACCAGTTGTTAGTATTGTTTCTGGAAACTGCTTGCCAAGACAACATTTA TTAACTGTTAGAACACTTGCTTTATGTTTGTGTGTACATATTTTCCACAAATGTTATAAT TTATATAGTGTGGTTGAACAGGATGCAATCTTTTGTTGTCTAAAGGTGCTGCAGTTAAAA AAAAAAACAACCTTTTCTTTCAATATGGCATGTAGTGGAGTTTTTTTAACTTTAAAAACA TCAAAAATTGTTAAAATCATTGTGTTATCTAGTAGTTTATAATTATCGGCTTATATTTCC CCATGAATGATCAGAACTGACATTTAATTCATGTTTGTCTCGCCATGCTTCTTTACTTTA ACATATTTCTTTTGCAGAATGTAAAAGGTAATGATAATTAGTTTATATAAGTGTACTGGC TGTAAATGATGCTAAATATACTTTATGCAATTAAGGGCTTACAGAACATGTTGAAACTTT TTTTACTTTTATTGGGAATAAGGAATGTTTGCACCTCCACATTTTATTGCTTCTGGATGT GAAATCATGTAATTATTTCTGCTGTTATATAAAGTGCCATACTTTTAATAAAGGAAAATG TACATATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_014363 unedited
GGCCATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCAGATCCACTAGTAACGGCCG CCAGTGTGCTGGAATTCGCCCTTACGCCACCACTTGTTGATTTTCTCAAGGACATTTTGA GAAGATATCCAGAAGGAGGACAGATTCTTAAGGAATTAATTCAGAATGCAGAAGATGCTG GGGCGACAGAAGTTAAATTTTTATATGATGAAACTCAATACGGAACAGAGACTCTTTGGT CAAAAGATATGGCGCCATATCAGGGGCCAGCTCTCTATGTGTACAACAACGCGGTTTTCA CCCCAGAGGACTGGCACGGCATTCAAGAAATAGCAAGAAGCAGGAAAAAGGATGATCCTC TGAAGGTCGGAAGATTTGGAATTGGGTTTAATTCTGTCTATCATATAACAGATGTTCCTT GTATCTTTAGTGGTGACCAAATCGGGATGCTAGATCCTCATCAAACACTTTTTGGCCCAC ATGAATCAGGCCAATGTTGGAAACTCAAAGATGACAGCAAAGAAATTAGTGAACTTTCAG ACCAGTTTGCACCATTTGTTGGCATTTTTGGAAGCACCAAGGAAACATTTATAAACGGCA ATTTTCCAGGAACATTTTTCCGTTTCCCTCTTCGCCTACAACCTTCACAACTTAGTAGTA ACCTCTACAATAAGCAGAAGGTTCTTGAGTTGTTTGAGTCTTTTAGGGCAGATGCAGACA CAGTGCTGCTCTTTCTGAAAAGTGTGCAGGATGTTTCCTTATATGTCCGAGAGGCTGACG GAACAGAGAAACTGGTGTTTAGAGTGACTTCGAGTGAGAGTAAGGCACTGAAACATGAGC GGCCGAATTCTATAAAGATTCTGGGAACTGCTATAAGTACTATTGTAAAAGACTCCAAGC AATAACATCACCTGTGTAACATATCACGTAATATTTGTTTTTAGAAGAGGAGGAGTACCT AAA >OriGene 3' read for NM_014363 unedited
CGTTGATGCACTTCAGGGCCGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGG ATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAATGTCCATTTTCCTTTATTAAAAGT TTGGCCCTTTATATAACAGCAGAAATAATTCCATGATTTCCCATCCAGAAGCAATAAAAT GGGGGGGTGCAAACTTTCCTTTTTCCCAATAAAAGTAAAAAAAGTTTCAACATGTTTTGT AAGCCCTTAATTGCATAAAGTTTTTTTAGCATCTTTTACCGCCAGTCCATTTTTTTAAAC TAATTTTTATTACCTTTTACATTTTGCAAAAAAAATATGTTAAAGTAAAAAAGCATGGCG AGACAAACATGAATTAAATGTCAGTTTTGATCATTCATGGGGAAATTTAACCCGATAATT ATAAACTATTAAATAACAAAATGATTTAAACAATTTTTGATGTTTTTAAAGTTAAAAAAA CTCCCTTACATGCCATATTGAAGAAAGGTGGGTTTTTTTTTAACTGCGCACTTTGGCCAC AAGATGGCTTCTGTCCACCACACTATAATTAACCTTGGGAAATGTCCACCAACCTAAGCA GTGTTCACGTATAATGTGCTGGCAGCATTCAACCACACACTGCAAGACTGCACATTGGTT CGTCTACTCTCACAGCCCTGTACTAAGTTCAAAATTATAGTTAAGTGACTAGTGACTGAG ATCTCGACTTAGTCAGTATAGTATTCCATCATCCGTATCACTAATACATCTG |
| Restriction Sites | Please inquire |
| ACCN | NM_014363 |
| Insert Size | 15000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | There is 7 nucleotide difference between the OriGene clone and the NCBI reference ORF. These result in the substitution of 1 aa and insertion of 1 aa. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014363.3, NP_055178.2 |
| RefSeq Size | 14805 bp |
| RefSeq ORF | 13299 bp |
| Locus ID | 26278 |
| UniProt ID | Q9NZJ4 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes the sacsin protein, which includes a UbL domain at the N-terminus, a DnaJ domain, and a HEPN domain at the C-terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12.8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disorder characterized by early-onset cerebellar ataxia with spasticity and peripheral neuropathy. The authors of a publication on the effects of siRNA-mediated sacsin knockdown concluded that sacsin protects against mutant ataxin-1 and suggest that "the large multi-domain sacsin protein is able to recruit Hsp70 chaperone action and has the potential to regulate the effects of other ataxia proteins" (Parfitt et al., PubMed: 19208651). A pseudogene associated with this gene is located on chromosome 11. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignment of partial transcripts and data in published reports. |
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