EHMT1/GLP (EHMT1) (NM_024757) Human Untagged Clone
CAT#: SC328062
EHMT1 (untagged)-Human euchromatic histone-lysine N-methyltransferase 1 (EHMT1) transcript variant 1
CNY 9,952.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | EHMT1-IT1; Eu-HMTase1; EUHMTASE1; FP13812; GLP; GLP1; KLEFS1; KMT1D |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Restriction Sites | Please inquire |
ACCN | NM_024757 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_024757.4, NP_079033.4 |
RefSeq Size | 5123 bp |
RefSeq ORF | 3897 bp |
Locus ID | 79813 |
UniProt ID | Q9H9B1 |
Domains | SET, ANK, PreSET, Pre-SET |
Protein Families | Druggable Genome |
Protein Pathways | Lysine degradation |
Gene Summary | The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Documents
Product Manuals |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC214949 | EHMT1 (Myc-DDK-tagged)-Human euchromatic histone-lysine N-methyltransferase 1 (EHMT1), transcript variant 1 |
CNY 12,920.00 |
|
RC214949L3 | Lenti-ORF clone of EHMT1 (Myc-DDK-tagged)-Human euchromatic histone-lysine N-methyltransferase 1 (EHMT1), transcript variant 1 |
CNY 14,820.00 |
|
RC214949L4 | Lenti-ORF clone of EHMT1 (mGFP-tagged)-Human euchromatic histone-lysine N-methyltransferase 1 (EHMT1), transcript variant 1 |
CNY 14,820.00 |
|
RG214949 | EHMT1 (tGFP-tagged) - Human euchromatic histone-lysine N-methyltransferase 1 (EHMT1), transcript variant 1 |
CNY 15,152.00 |
|
SC112042 | EHMT1 (untagged)-Human euchromatic histone-lysine N-methyltransferase 1 (EHMT1), transcript variant 1 |
CNY 25,080.00 |
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