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SETMAR (NM_006515) Human Untagged Clone
CAT＃: SC327972
SETMAR (untagged)-Human SET domain and mariner transposase fusion gene (SETMAR)
CNY 13,210.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Mar1; METNASE |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC327972 representing NM_006515.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGTTCGCGGAAGCGGCAAAGACGACACGGCCTTGTGGGATGGCGGAGTTTAAGGAGAAGCCTGAGGCC CCGACTGAGCAGCTGGATGTCGCGTGCGGCCAGGAAAACTTGCCGGTGGGCGCGTGGCCCCCGGGGGCC GCGCCGGCGCCCTTCCAGTACACTCCTGATCATGTAGTTGGACCTGGAGCAGACATTGATCCCACTCAA ATAACCTTTCCCGGATGCATTTGTGTCAAAACTCCCTGCCTCCCTGGCACTTGCTCCTGTCTCCGCCAT GGAGAGAACTATGATGATAACTCATGCCTTAGAGATATAGGATCTGGAGGAAAGTATGCAGAGCCTGTT TTTGAATGCAATGTCCTGTGCCGATGCAGTGACCACTGCAGAAACAGAGTGGTCCAGAAAGGTCTACAG TTCCACTTCCAAGTGTTCAAGACGCATAAAAAAGGCTGGGGACTTCGTACCTTGGAATTTATACCGAAA GGAAGGTTTGTCTGTGAATATGCTGGTGAGGTTTTAGGATTCTCTGAAGTTCAGAGAAGAATTCACTTA CAAACAAAATCCGACTCCAATTACATTATAGCCATCAGGGAACATGTTTATAATGGGCAGGTAATGGAA ACATTTGTTGACCCTACTTATATAGGAAATATTGGAAGATTCCTTAATCATTCTTGTGAGCCAAACCTT TTGATGATTCCTGTCCGAATTGACTCAATGGTACCTAAGTTGGCACTTTTTGCAGCCAAAGATATTGTG CCAGAAGAAGAACTCTCTTATGATTATTCAGGAAGATATCTTAATCTAACAGTCAGTGAAGACAAAGAA AGGCTAGATCATGGGAAACTAAGGAAACCTTGTTACTGTGGTGCCAAATCATGTACTGCTTTCCTGCCT TTTGACAGTTCTCTGTACTGCCCCGTAGAAAAGTCGAACATCAGTTGTGGAAATGAGAAGGAACCCAGC ATGTGTGGCTCAGCCCCTTCTGTGTTCCCCTCCTGCAAGCGATTGACCCTTGAGACTATGAAAATGATG TTAGACAAAAAGCAAATTCGAGCAATTTTCTTATTCGAGTTCAAAATGGGTCGTAAAGCAGCAGAAACA ACTCGCAACATCAACAATGCATTTGGCCCAGGAACTGCTAACGAACGTACAGTGCAGTGGTGGTTCAAG AAGTTTTGCAAAGGAGATGAGAGCCTTGAAGATGAGGAGCGTAGTGGCCGGCCATCAGAAGTTGACAAC GACCAGTTGAGAGCAATCATCGAAGCTGATCCCCTTACAACTACACGAGAAGTTGCTGAAGAACTCAAT GTCAACCATTCTACGGTCGTTCGACATTTGAAGCAAATTGGAAAGGTGAAAAAGCTCGATAAGTGGGTG CCTCATGAGCTGACTGAAAATCAAAAAAATCGTCGTTTTGAAGTGTCATCTTCTCTTATTCTACGCAAC CACAACGAACCATTTCTCGATCGGATTGTGACGTGTGATGAAAAGTGGATTTTATATGACAACCGGCGA CGATCAGCTCAGTGGTTGGATCAAGAAGAAGCTCCAAAGCACTTCCCAAAGCCAATCTTGCACCCAAAA AAGGTCATGGTCACTATTTGGTGGTCTGCTGCTGGTCTGATCCACTACAGCTTTCTGAATCCCGGTGAA ACCATTACATCTGAGAAGTATGCTCAGGAAATCGATGAGATGAACCAAAAACTGCAACGCCTGCAGCTG GCATTGGTCAACAGAAAGGGCCCAATTCTTCTCCACGACAATGCCCGACCGCATGTTGCACAACCCACA CTTCAAAAGTTGAATGAATTGGGCTATGAAGTTTTGCCTCATCCACCGTATTCACCTGACCTCTTGCCA ACCAACTACCACGTCTTTAAGCATCTCAACAACTTTTTGCAGGGAAAACGCTTCCACAACCAGCAGGAT GCAGAAAATGCTTTCCAAGAGTTCGTCGAATCCCAAAGCACGGATTTTTACGCTACAGGAATAAACCAA CTTATTTCTCGTTGGCAAAAATGTGTTGATTGTAATGGTTCCTATTTTGATTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_006515 |
| Insert Size | 2055 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006515.3 |
| RefSeq Size | 2157 bp |
| RefSeq ORF | 2055 bp |
| Locus ID | 6419 |
| UniProt ID | Q53H47 |
| Domains | SET, Transposase_1, PreSET, Pre-SET |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Lysine degradation |
| MW | 78 kDa |
| Gene Summary | This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC229337 | SETMAR (Myc-DDK-tagged)-Human SET domain and mariner transposase fusion gene (SETMAR) |
CNY 5,008.00 |
|
| RC229337L1 | Lenti ORF clone of Human SET domain and mariner transposase fusion gene (SETMAR), Myc-DDK-tagged |
CNY 7,408.00 |
|
| RC229337L2 | Lenti ORF clone of Human SET domain and mariner transposase fusion gene (SETMAR), mGFP tagged |
CNY 7,700.00 |
|
| RC229337L3 | Lenti ORF clone of Human SET domain and mariner transposase fusion gene (SETMAR), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC229337L4 | Lenti ORF clone of Human SET domain and mariner transposase fusion gene (SETMAR), mGFP tagged |
CNY 7,700.00 |
|
| RG229337 | SETMAR (tGFP-tagged) - Human SET domain and mariner transposase fusion gene (SETMAR) |
CNY 6,370.00 |
|
| SC314383 | SETMAR (untagged)-Human SET domain and mariner transposase fusion gene (SETMAR) |
CNY 13,210.00 |
