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SH2B2 (NM_020979) Human Untagged Clone
CAT＃: SC327968
SH2B2 (untagged)-Human SH2B adaptor protein 2 (SH2B2)
CNY 13,110.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APS |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC327968 representing NM_020979.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGATCCAAGCTATTGTCCTGCCCATGGCTTCCCATCTCAGGACCCTCTCTGGCCGCTATCATCCCAG CAGTGGAGTTCAGCCCACTACTCTGAACCAGCCGCAGGTGGCTGCGATGGGACGGAAGCCATGAATGGT GCCGGCCCTGGCCCCGCCGCAGCCGCCCCGGTCCCAGTCCCGGTCCCGGTCCCGGACTGGCGGCAGTTC TGCGAGCTGCATGCGCAGGCGGCCGCCGTGGACTTTGCGCACAAGTTCTGCCGTTTCCTGCGGGACAAC CCAGCTTACGACACGCCCGACGCCGGCGCCTCCTTCTCCCGCCACTTCGCCGCCAACTTCCTGGACGTC TTCGGCGAGGAGGTGCGCCGCGTGCTGGTGGCTGGGCCGACGACTCGGGGCGCGGCCGTGAGCGCAGAG GCCATGGAGCCGGAGCTCGCGGACACCTCTGCACTCAAGGCGGCGCCCTACGGCCACTCGCGGAGCTCG GAGGACGTGTCCACGCACGCGGCCACCAAGGCCCGCGTTCGCAAGGGCTTCTCGCTGCGCAACATGAGC CTGTGCGTGGTGGACGGCGTGCGCGACATGTGGCACCGGCGCGCCTCGCCCGAGCCCGACGCGGCAGCT GCCCCGCGCACCGCCGAGCCCCGCGACAAGTGGACGCGGCGCCTGAGGCTGTCGCGGACGCTGGCTGCC AAGGTGGAGCTGGTGGACATTCAACGCGAGGGGGCGCTGCGCTTCATGGTGGCCGACGACGCGGCCGCG GGCTCCGGGGGCTCGGCTCAGTGGCAGAAGTGCCGCCTGCTCCTGCGCAGGGCTGTGGCCGAGGAACGC TTCCGCCTGGAGTTCTTCGTGCCGCCCAAAGCCTCCAGGCCCAAGGTCAGCATCCCACTGTCAGCCATC ATTGAGGTCCGCACCACCATGCCCCTGGAAATGCCAGAGAAGGATAACACATTCGTCCTCAAGGTAGAG AATGGAGCCGAATACATCTTGGAGACCATCGACTCTCTGCAGAAGCACTCGTGGGTAGCTGACATCCAG GGCTGCGTGGACCCCGGTGACAGTGAGGAAGACACCGAGCTCTCCTGTACCCGAGGAGGCTGTCTGGCC AGCCGCGTGGCCTCCTGCAGCTGTGAGCTCCTGACTGATGCAGTCGACCTGCCCCGCCCCCCAGAGACG ACAGCCGTGGGTGCAGTGGTGACAGCCCCCCACAGCCGAGGTCGAGATGCCGTCAGAGAATCCCTGATC CACGTCCCGCTAGAGACCTTTCTGCAGACCCTGGAATCCCCGGGCGGCAGCGGCAGTGACAGCAATAAC ACAGGGGAACAGGGTGCAGAGACGGATCCCGAGGCTGAACCCGAGCTGGAGCTATCCGACTACCCATGG TTCCACGGGACACTGTCCCGGGTCAAGGCTGCTCAACTGGTTCTGGCAGGGGGGCCCCGGAACCACGGC CTCTTCGTGATCCGCCAAAGTGAGACTCGGCCTGGGGAGTACGTGCTGACCTTCAACTTCCAGGGCAAG GCCAAGCACCTGCGCCTGTCCCTGAACGGCCACGGCCAGTGTCACGTACAGCATCTGTGGTTCCAGTCT GTGCTTGACATGCTCCGCCACTTCCACACACACCCCATCCCACTGGAGTCAGGGGGCTCGGCCGACATC ACCCTTCGCAGCTATGTGCGGGCCCAGGACCCCCCACCAGAGCCGGGCCCCACGCCCCCTGCCGCGCCC GCGTCCCCGGCCTGCTGGAGCGACTCGCCCGGCCAGCACTACTTCTCCAGCCTCGCCGCGGCCGCCTGC CCGCCTGCCTCGCCCTCCGACGCCGCCGGCGCCTCCTCGTCTTCCGCCTCGTCGTCCTCTGCCGCGTCG GGGCCCGCCCCCCCGCGCCCCGTCGAGGGCCAGCTCAGCGCGCGGAGCCGCAGCAACAGCGCCGAGCGC CTGCTGGAGGCCGTGGCCGCCACCGCCGCCGAGGAGCCCCCGGAGGCCGCGCCCGGCCGCGCGCGCGCC GTGGAGAACCAGTACTCCTTCTACTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_020979 |
| Insert Size | 2028 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_020979.4 |
| RefSeq Size | 2226 bp |
| RefSeq ORF | 2028 bp |
| Locus ID | 10603 |
| UniProt ID | O14492 |
| Domains | SH2, PH |
| Protein Families | Druggable Genome |
| Protein Pathways | Insulin signaling pathway, Neurotrophin signaling pathway |
| MW | 72.3 kDa |
| Gene Summary | The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq, Jun 2009] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC229333 | SH2B2 (Myc-DDK-tagged)-Human SH2B adaptor protein 2 (SH2B2) |
CNY 4,944.00 |
|
| RC229333L3 | Lenti ORF clone of Human SH2B adaptor protein 2 (SH2B2), Myc-DDK-tagged |
CNY 9,120.00 |
|
| RC229333L4 | Lenti ORF clone of Human SH2B adaptor protein 2 (SH2B2), mGFP tagged |
CNY 9,120.00 |
|
| RG229333 | SH2B2 (tGFP-tagged) - Human SH2B adaptor protein 2 (SH2B2) |
CNY 7,980.00 |
|
| SC314274 | SH2B2 (untagged)-Human SH2B adaptor protein 2 (SH2B2) |
CNY 4,712.00 |
