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FBXW12 (NM_001159929) Human Untagged Clone
CAT＃: SC327536
FBXW12 (untagged)-Human F-box and WD repeat domain containing 12 (FBXW12) transcript variant 3
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FBW12; FBXO12; FBXO35 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001159929, the custom clone sequence may differ by one or more nucleotides
ATGAGCCCCACTCACCAGATTCAAGATCCCAAGCATTGGAATAGGATTGCAGACAGTGAT TACCTGTGGAGGTCACTATCTCTGCAGAGATGGGACTGCAGCAACTTCACCAATCAACAC CTGGGCACACACACATGGAAGCAATTTTTCCTGCATCAAAGAAGGAAGGAGCTTCGGTTG GCATTGGCACAGCCGCATAACTTTATCTACAAAGTAACTAAGAACATCGCATTTGAGACG GAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATT TGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATC TGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCAT CTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGAC GCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAG GATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCT GGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGC TCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTA TTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTC CCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTG ATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAG AAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCT CATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGT GGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCAT CAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAAC TCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGT CACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGT GATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATG TATTCTTTGAATACG |
| Restriction Sites | Please inquire |
| ACCN | NM_001159929 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001159929.1, NP_001153401.1 |
| RefSeq Size | 1473 bp |
| RefSeq ORF | 1338 bp |
| Locus ID | 285231 |
| UniProt ID | Q6X9E4 |
| Protein Families | Druggable Genome |
| Gene Summary | Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC228901 | FBXW12 (Myc-DDK-tagged)-Human F-box and WD repeat domain containing 12 (FBXW12), transcript variant 3 |
CNY 3,990.00 |
|
| RC228901L3 | Lenti-ORF clone of FBXW12 (Myc-DDK-tagged)-Human F-box and WD repeat domain containing 12 (FBXW12), transcript variant 3 |
CNY 5,890.00 |
|
| RC228901L4 | Lenti-ORF clone of FBXW12 (mGFP-tagged)-Human F-box and WD repeat domain containing 12 (FBXW12), transcript variant 3 |
CNY 5,890.00 |
|
| RG228901 | FBXW12 (tGFP-tagged) - Human F-box and WD repeat domain containing 12 (FBXW12), transcript variant 3 |
CNY 4,370.00 |
