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S adenosylhomocysteine hydrolase (AHCY) (NM_001161766) Human Untagged Clone
CAT＃: SC327515
AHCY (untagged)-Human adenosylhomocysteinase (AHCY) transcript variant 2
CNY 7,220.00
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | adoHcyase; SAHH |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001161766, the custom clone sequence may differ by one or more nucleotides
ATGCCGGGCCTGATGCGTATGCGGGAGCGGTACTCGGCCTCCAAGCCACTGAAGGGCGCC CGCATCGCTGGCTGCCTGCACATGACCGTGGAGACGGCCGTCCTCATTGAGACCCTCGTC ACCCTGGGTGCTGAGGTGCAGTGGTCCAGCTGCAACATCTTCTCCACCCAGGACCATGCG GCGGCTGCCATTGCCAAGGCTGGCATTCCGGTGTATGCCTGGAAGGGCGAAACGGACGAG GAGTACCTGTGGTGCATTGAGCAGACCCTGTACTTCAAGGACGGGCCCCTCAACATGATT CTGGACGACGGGGGCGACCTCACCAACCTCATCCACACCAAGTACCCGCAGCTTCTGCCA GGCATCCGAGGCATCTCTGAGGAGACCACGACTGGGGTCCACAACCTCTACAAGATGATG GCCAATGGGATCCTCAAGGTGCCTGCCATCAATGTCAATGACTCCGTCACCAAGAGCAAG TTTGACAACCTCTATGGCTGCCGGGAGTCCCTCATAGATGGCATCAAGCGGGCCACAGAT GTGATGATTGCCGGCAAGGTAGCGGTGGTAGCAGGCTATGGTGATGTGGGCAAGGGCTGT GCCCAGGCCCTGCGGGGTTTCGGAGCCCGCGTCATCATCACCGAGATTGACCCCATCAAC GCACTGCAGGCTGCCATGGAGGGCTATGAGGTGACCACCATGGATGAGGCCTGTCAGGAG GGCAACATCTTTGTCACCACCACAGGCTGTATTGACATCATCCTTGGCCGGCACTTTGAG CAGATGAAGGATGATGCCATTGTGTGTAACATTGGACACTTTGACGTGGAGATCGATGTC AAGTGGCTCAACGAGAACGCCGTGGAGAAGGTGAACATCAAGCCGCAGGTGGACCGGTAT CGGTTGAAGAATGGGCGCCGCATCATCCTGCTGGCCGAGGGTCGGCTGGTCAACCTGGGT TGTGCCATGGGCCACCCCAGCTTCGTGATGAGTAACTCCTTCACCAACCAGGTGATGGCG CAGATCGAGCTGTGGACCCATCCAGACAAGTACCCCGTTGGGGTTCATTTCCTGCCCAAG AAGCTGGATGAGGCAGTGGCTGAAGCCCACCTGGGCAAGCTGAATGTGAAGTTGACCAAG CTAACTGAGAAGCAAGCCCAGTACCTGGGCATGTCCTGTGATGGCCCCTTCAAGCCGGAT CACTACCGCTAC |
| Restriction Sites | Please inquire |
| ACCN | NM_001161766 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001161766.1, NP_001155238.1 |
| RefSeq Size | 2375 bp |
| RefSeq ORF | 1215 bp |
| Locus ID | 191 |
| UniProt ID | P23526 |
| Protein Families | Druggable Genome |
| Protein Pathways | Cysteine and methionine metabolism, Metabolic pathways, Selenoamino acid metabolism |
| Gene Summary | S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009] Transcript Variant: This variant (2) has an alternate 5' exon and uses a downstream AUG start codon, as compared to variant 1. The resulting isoform (2) has a shorter N-terminus, as compared to isoform 1. Variants 2, 4 and 5 encode the same isoform (2). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC228880 | AHCY (Myc-DDK-tagged)-Human adenosylhomocysteinase (AHCY), transcript variant 2 |
CNY 4,280.00 |
|
| RC228880L3 | Lenti-ORF clone of AHCY (Myc-DDK-tagged)-Human adenosylhomocysteinase (AHCY), transcript variant 2 |
CNY 6,180.00 |
|
| RC228880L4 | Lenti-ORF clone of AHCY (mGFP-tagged)-Human adenosylhomocysteinase (AHCY), transcript variant 2 |
CNY 6,180.00 |
|
| RG228880 | AHCY (tGFP-tagged) - Human adenosylhomocysteinase (AHCY), transcript variant 2 |
CNY 4,750.00 |
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