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CTNNA2 (NM_001164883) Human Untagged Clone
CAT＃: SC327233
CTNNA2 (untagged)-Human catenin (cadherin-associated protein) alpha 2 (CTNNA2) transcript variant 2
CNY 16,630.00
Product images
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAP-R; CAPR; CDCBM9; CT114; CTNR |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001164883, the custom clone sequence may differ by one or more nucleotides
ATGACTTCGGCAACTTCACCTATCATTCTGAAATGGGACCCCAAAAGTTTGGAAATCCGG ACGCTAACAGTGGAAAGGCTGTTGGAGCCACTTGTTACACAGGTGACTACACTTGTCAAC ACAAGCAACAAAGGCCCATCTGGTAAAAAGAAAGGGAGGTCAAAGAAAGCCCATGTACTA GCTGCCTCTGTAGAGCAAGCCACTCAGAATTTCCTGGAAAAGGGTGAACAGATCGCTAAG GAGAGTCAAGATCTCAAAGAAGAGTTGGTGGCTGCTGTAGAGGATGTGCGCAAACAAGGT GAGACGATGCGGATCGCCTCCTCCGAGTTTGCAGATGACCCTTGCTCGTCGGTAAAGCGC GGCACCATGGTACGGGCGGCAAGGGCTTTGCTCTCCGCGGTGACACGCTTACTCATCCTG GCGGACATGGCAGATGTCATGAGACTTTTATCCCATCTGAAAATTGTGGAAGAGGCCCTG GAAGCTGTCAAAAATGCTACAAATGAGCAAGACCTTGCAAACCGTTTTAAAGAGTTTGGG AAAGAGATGGTGAAACTTAACTATGTAGCAGCAAGAAGACAACAGGAGCTGAAGGATCCT CACTGTCGGGATGAGATGGCAGCCGCCCGAGGGGCTCTGAAGAAGAATGCCACAATGCTG TACACGGCCTCTCAAGCATTTCTCCGCCACCCAGATGTCGCCGCTACGAGAGCCAACCGA GATTATGTGTTCAAACAAGTCCAGGAGGCCATCGCCGGCATCTCCAATGCTGCTCAAGCT ACCTCGCCCACTGACGAAGCCAAGGGCCACACGGGCATCGGCGAGCTGGCTGCGGCTCTT AATGAGTTTGACAATAAGATTATCCTGGACCCCATGACGTTCAGCGAGGCCAGGTTCCGG CCGTCCCTGGAGGAGAGGCTGGAGAGCATCATCAGCGGCGCAGCGCTGATGGCCGACTCC TCCTGCACGCGAGACGACCGGCGCGAGAGGATCGTGGCGGAGTGCAACGCCGTGCGGCAG GCGCTCCAGGACCTGCTCAGCGAGTACATGAATAATACTGGAAGGAAAGAAAAAGGAGAT CCTCTCAACATTGCGATTGATAAGATGACTAAGAAAACAAGAGATCTAAGGAGACAGCTT CGGAAAGCAGTGATGGATCACATATCTGACTCTTTCCTGGAAACCAATGTTCCTTTGCTA GTTCTCATTGAGGCTGCAAAGAGCGGAAATGAAAAGGAAGTGAAAGAATATGCCCAAGTT TTCCGTGAGCATGCCAACAAACTGGTAGAGGTTGCCAATTTGGCCTGTTCCATCTCCAAC AATGAAGAAGGGGTGAAATTAGTTCGGATGGCAGCCACCCAGATTGACAGCCTGTGTCCC CAGGTCATCAATGCCGCTCTGACACTGGCTGCCCGGCCACAGAGCAAAGTTGCTCAGGAT AACATGGACGTCTTCAAAGACCAGTGGGAGAAGCAGGTCCGAGTGTTGACAGAGGCCGTG GATGACATCACCTCAGTGGATGACTTCCTCTCTGTCTCAGAAAATCACATCTTGGAGGAT GTGAACAAGTGTGTGATAGCCCTCCAAGAGGGCGATGTGGACACTCTGGACCGGACTGCA GGGGCCATCAGGGGCCGGGCAGCTCGAGTCATACACATCATCAATGCTGAGATGGAGAAC TATGAAGCTGGGGTTTATACTGAGAAGGTGTTGGAAGCTACAAAATTGCTTTCTGAAACA GTGATGCCACGCTTCGCTGAACAAGTAGAGGTTGCCATTGAAGCCCTGAGTGCCAACGTT CCTCAACCGTTTGAGGAGAATGAGTTCATCGATGCCTCTCGCCTGGTGTATGATGGCGTT CGGGACATCAGAAAGGCTGTGCTGATGATCAGGACCCCAGAAGAACTAGAGGATGATTCT GACTTTGAGCAGGAAGATTATGATGTGCGTAGCAGGACAAGTGTTCAGACTGAGGATGAC CAGCTCATTGCAGGGCAGAGCGCACGGGCCATCATGGCGCAACTACCGCAGGAGGAGAAG GCAAAAATAGCTGAGCAGGTGGAGATATTCCATCAAGAGAAAAGCAAGCTGGATGCAGAA GTGGCCAAATGGGACGACAGCGGCAATGATATCATTGTACTGGCCAAGCAGATGTGTATG ATCATGATGGAAATGACAGACTTCACAAGAGGCAAAGGCCCATTGAAAAATACATCTGAT GTCATTAATGCTGCCAAGAAAATTGCCGAAGCAGGTTCTCGAATGGACAAATTAGCTCGT GCTGTGGCTGATCAGCTGGACAGTGCCACATCGCTTATCCAGGCAGCTAAAAACCTGATG AATGCTGTTGTCCTCACGGTGAAAGCATCCTATGTGGCCTCAACCAAATACCAGAAGGTC TATGGGACAGCAGCTGTCAACTCACCTGTTGTGTCTTGGAAGATGAAGGCTCCAGAGAAG AAGCCCCTTGTGAAGAGAGAAAAGCCTGAAGAATTCCAGACACGAGTTCGACGAGGTTCT CAGAAGAAACACATTTCGCCTGTACAGGCTTTAAGTGAATTCAAAGCAATGGATTCCTTC |
| Restriction Sites | Please inquire |
| ACCN | NM_001164883 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001164883.1, NP_001158355.1 |
| RefSeq Size | 3870 bp |
| RefSeq ORF | 2583 bp |
| Locus ID | 1496 |
| UniProt ID | P26232 |
| Protein Families | Druggable Genome |
| Protein Pathways | Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Endometrial cancer, Leukocyte transendothelial migration, Pathways in cancer, Tight junction |
| Gene Summary | May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system (By similarity). Required for proper regulation of cortical neuronal migration and neurite growth (PubMed:30013181). It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization (PubMed:30013181). It thereby suppresses excessive actin branching which would impair neurite growth and stability (PubMed:30013181). Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks two consecutive exons in the 3' coding region but maintains the reading frame compared to variant 1. The resulting isoform (2) lacks an internal segment near the C-terminus compared to isoform 3. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC228598 | CTNNA2 (Myc-DDK-tagged)-Human catenin (cadherin-associated protein), alpha 2 (CTNNA2), transcript variant 2 |
CNY 9,120.00 |
|
| RC228598L3 | Lenti-ORF clone of CTNNA2 (Myc-DDK-tagged)-Human catenin (cadherin-associated protein), alpha 2 (CTNNA2), transcript variant 2 |
CNY 11,020.00 |
|
| RC228598L4 | Lenti-ORF clone of CTNNA2 (mGFP-tagged)-Human catenin (cadherin-associated protein), alpha 2 (CTNNA2), transcript variant 2 |
CNY 11,020.00 |
|
| RG228598 | CTNNA2 (tGFP-tagged) - Human catenin (cadherin-associated protein), alpha 2 (CTNNA2), transcript variant 2 |
CNY 10,070.00 |
